iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067033

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02002020

Gene Name

TRIM35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000004435.2	ENSMLUT00000004433.2	ENSMLUP00000004036.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.10e-08	32.6	21	61
E3 activity/RING/U-box	1.90e-10	40.7	15	84

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           Ca+C+++f+d  ++l+CgH f+++C+  +w     + +++ +CP+C+
   Q: 21   CAVCYDPFRD-AVTLRCGHNFCRECVtRCW-----EVQTTPTCPVCK 61
           ********99.999***********99999.....899********7 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggk.tcPvtrqplteedlvPnltlrrliqawce 70
           + ee+lC++ ++++rd v+l +G+ + r+++ ++ + + + tcPv++ ++++ dl  n+tl +l+++ + 
   Q: 15   IKEELLCAVCYDPFRDAVTLRCGHNFCRECVTRCWEVQTTpTCPVCKDRVAPADLRTNHTLNNLVEKLLR 84
           789*******************************9888888***********************998665 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MESEPSLSPT LSRSIKEELL CAVCYDPFRD AVTLRCGHNF CRECVTRCWE VQTTPTCPVC 60
KDRVAPADLR TNHTLNNLVE KLLREDTEGG RYAGHRSPRF CRAHRGQLSL FCIEDKELLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGTCGG AACCCTCGCT GTCCCCCACG CTTTCCCGCT CCATCAAGGA GGAGCTGCTC 60
TGCGCCGTCT GCTACGACCC CTTCCGGGAT GCCGTGACGC TGCGCTGCGG CCACAACTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0045930--P:negative regulation of mitotic cell cycle
GO:1902187--P:negative regulation of viral release from host cell
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001788	Ailuropoda melanoleuca	86.79	0.00e+00	902.00
IUUC-Apl-003958	Anas platyrhynchos	52.92	1.00e-129	456.00
IUUC-Aca-005199	Anolis carolinensis	46.49	3.00e-126	445.00
IUUC-Ame-011964	Astyanax mexicanus	35.28	2.00e-72	266.00
IUUC-Bta-013359	Bos taurus	84.38	0.00e+00	873.00
IUUC-Cja-018900	Callithrix jacchus	73.15	0.00e+00	739.00
IUUC-Cfa-020685	Canis familiaris	87.20	0.00e+00	903.00
IUUC-Cpo-022253	Cavia porcellus	76.88	0.00e+00	757.00
IUUC-Csa-023777	Chlorocebus sabaeus	85.37	0.00e+00	884.00
IUUC-Dre-028296	Danio rerio	32.80	1.00e-71	263.00
IUUC-Dno-029065	Dasypus novemcinctus	83.47	0.00e+00	856.00
IUUC-Dor-030248	Dipodomys ordii	61.60	4.00e-95	340.00
IUUC-Ete-033183	Echinops telfairi	71.40	0.00e+00	711.00
IUUC-Eca-033263	Equus caballus	87.17	0.00e+00	791.00
IUUC-Eeu-034699	Erinaceus europaeus	79.41	1.00e-114	406.00
IUUC-Fca-036366	Felis catus	86.38	0.00e+00	893.00
IUUC-Fal-037257	Ficedula albicollis	54.70	4.00e-152	531.00
IUUC-Gmo-038512	Gadus morhua	34.72	3.00e-67	249.00
IUUC-Gga-041125	Gallus gallus	54.23	2.00e-106	378.00
IUUC-Gac-042136	Gasterosteus aculeatus	35.21	4.00e-70	258.00
IUUC-Ggo-045233	Gorilla gorilla	86.67	5.00e-165	573.00
IUUC-Hsa-046042	Homo sapiens	85.77	0.00e+00	885.00
IUUC-Itr-048751	Ictidomys tridecemlineatus	83.57	0.00e+00	859.00
IUUC-Lch-049548	Latimeria chalumnae	35.16	3.00e-81	295.00
IUUC-Loc-051729	Lepisosteus oculatus	34.71	1.00e-80	293.00
IUUC-Laf-054322	Loxodonta africana	85.56	0.00e+00	864.00
IUUC-Mcc-055555	Macaca mulatta	83.33	0.00e+00	865.00
IUUC-Meu-055900	Macropus eugenii	76.12	0.00e+00	772.00
IUUC-Mga-059380	Meleagris gallopavo	54.88	1.00e-100	359.00
IUUC-Mmr-061296	Microcebus murinus	83.54	0.00e+00	853.00
IUUC-Mdo-062811	Monodelphis domestica	77.99	0.00e+00	777.00
IUUC-Mmu-063718	Mus musculus	75.40	0.00e+00	778.00
IUUC-Mpu-066219	Mustela putorius furo	86.18	0.00e+00	882.00
IUUC-Nle-069806	Nomascus leucogenys	85.03	0.00e+00	822.00
IUUC-Opr-070248	Ochotona princeps	75.35	0.00e+00	744.00
IUUC-Ont-072083	Oreochromis niloticus	31.76	2.00e-70	259.00
IUUC-Oan-073364	Ornithorhynchus anatinus	68.55	1.00e-99	355.00
IUUC-Ocu-074572	Oryctolagus cuniculus	84.55	0.00e+00	884.00
IUUC-Ola-086686	Oryzias latipes	32.37	4.00e-61	228.00
IUUC-Oga-088378	Otolemur garnettii	82.15	0.00e+00	841.00
IUUC-Oar-089516	Ovis aries	84.17	0.00e+00	855.00
IUUC-Ptr-091313	Pan troglodytes	85.77	0.00e+00	885.00
IUUC-Pan-092877	Papio anubis	85.57	0.00e+00	885.00
IUUC-Psi-093928	Pelodiscus sinensis	58.54	5.00e-162	563.00
IUUC-Pfo-096831	Poecilia formosa	33.81	4.00e-67	248.00
IUUC-Pab-098624	Pongo abelii	85.57	0.00e+00	879.00
IUUC-Pca-100469	Procavia capensis	79.96	0.00e+00	805.00
IUUC-Pva-103227	Pteropus vampyrus	87.40	0.00e+00	900.00
IUUC-Rno-105778	Rattus norvegicus	75.40	0.00e+00	779.00
IUUC-Sha-107392	Sarcophilus harrisii	67.81	0.00e+00	664.00
IUUC-Sar-113297	Sorex araneus	66.41	2.00e-50	192.00
IUUC-Ssc-115739	Sus scrofa	85.16	0.00e+00	867.00
IUUC-Tru-117718	Takifugu rubripes	32.77	3.00e-62	232.00
IUUC-Tni-120490	Tetraodon nigroviridis	34.44	1.00e-70	260.00
IUUC-Tbe-127926	Tupaia belangeri	70.04	0.00e+00	672.00
IUUC-Ttr-129293	Tursiops truncatus	86.18	0.00e+00	886.00
IUUC-Vpa-130379	Vicugna pacos	87.25	8.00e-154	535.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence