iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000011237.1	ENSAMET00000012488.1	ENSAMEP00000011982.1
ENSAMEG00000011237.1	ENSAMET00000012516.1	ENSAMEP00000012009.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.40e-18	64.5	779	830

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 8    vlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           + y++ a +  eL+l++Gdvv++ +    d+gW+kg  e++g+ G fP+ +ve+
   Q: 779  ARYNFAARDMRELSLREGDVVKIYSRIGGDQGWWKG--EANGRIGWFPSTYVEE 830
           67**********************************..9*************86 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

QLLHNLSPGS IDLKDINFRP QMSQFLCLKN IRTFLKVCHD KFGLRNSELF DPFDLFDVRD 60
FGKVISAVSR LSLHPVAQNK GIRPFPSEET AENDDDVYRS LEELADEHDL GEDIYDCVPC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCTCCTGC ACAACCTCTC CCCCGGCTCC ATCGACCTCA AGGACATCAA CTTCCGGCCG 60
CAGATGTCCC AGGTGAGGGT CCTGCGCGCG GGCGGGCGCG GGGAGAGAGG GGCGCGCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR022613--CAMSAP_CH
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF11971--CAMSAP_CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0016477--P:cell migration
GO:0030032--P:lamellipodium assembly
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:0030193--P:regulation of blood coagulation
GO:0008361--P:regulation of cell size
GO:0010468--P:regulation of gene expression
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003262	Anas platyrhynchos	88.73	0.00e+00	1441.00
IUUC-Ath-007352	Arabidopsis thaliana	39.22	8.00e-03	35.80
IUUC-Ame-011608	Astyanax mexicanus	78.21	0.00e+00	1332.00
IUUC-Bta-013147	Bos taurus	92.59	0.00e+00	1309.00
IUUC-Cel-018578	Caenorhabditis elegans	27.23	1.00e-86	315.00
IUUC-Cja-018877	Callithrix jacchus	91.48	0.00e+00	1409.00
IUUC-Cfa-020315	Canis familiaris	90.71	0.00e+00	1248.00
IUUC-Cpo-021543	Cavia porcellus	91.28	0.00e+00	1311.00
IUUC-Csa-024204	Chlorocebus sabaeus	91.20	0.00e+00	1499.00
IUUC-Dre-028308	Danio rerio	80.50	0.00e+00	1369.00
IUUC-Dno-029584	Dasypus novemcinctus	84.44	0.00e+00	1121.00
IUUC-Dor-031014	Dipodomys ordii	82.39	0.00e+00	1228.00
IUUC-Eca-033448	Equus caballus	92.09	0.00e+00	1493.00
IUUC-Eeu-035182	Erinaceus europaeus	84.04	0.00e+00	677.00
IUUC-Fca-035460	Felis catus	92.55	0.00e+00	1323.00
IUUC-Fal-036684	Ficedula albicollis	87.97	0.00e+00	1455.00
IUUC-Gmo-038816	Gadus morhua	74.67	0.00e+00	1087.00
IUUC-Gga-040999	Gallus gallus	84.65	0.00e+00	1400.00
IUUC-Gac-041353	Gasterosteus aculeatus	75.84	0.00e+00	1136.00
IUUC-Ggo-044558	Gorilla gorilla	93.17	0.00e+00	1509.00
IUUC-Hsa-046208	Homo sapiens	93.29	0.00e+00	1512.00
IUUC-Itr-047931	Ictidomys tridecemlineatus	88.53	0.00e+00	1183.00
IUUC-Loc-052827	Lepisosteus oculatus	80.50	0.00e+00	1370.00
IUUC-Laf-054009	Loxodonta africana	90.18	0.00e+00	1449.00
IUUC-Mcc-055054	Macaca mulatta	93.17	0.00e+00	1511.00
IUUC-Meu-056269	Macropus eugenii	83.44	0.00e+00	747.00
IUUC-Mla-059044	Melampsora laricipopulina	21.85	3.00e-19	90.90
IUUC-Mga-060106	Meleagris gallopavo	88.25	0.00e+00	1424.00
IUUC-Mmr-061118	Microcebus murinus	91.25	0.00e+00	1483.00
IUUC-Mdo-062380	Monodelphis domestica	85.55	0.00e+00	1279.00
IUUC-Mmu-063135	Mus musculus	92.93	0.00e+00	1513.00
IUUC-Mpu-066135	Mustela putorius furo	89.26	0.00e+00	1436.00
IUUC-Nle-069465	Nomascus leucogenys	85.46	0.00e+00	1355.00
IUUC-Ont-071945	Oreochromis niloticus	80.57	0.00e+00	1314.00
IUUC-Oan-073384	Ornithorhynchus anatinus	85.95	0.00e+00	1201.00
IUUC-Ola-087499	Oryzias latipes	75.86	0.00e+00	1068.00
IUUC-Oga-088444	Otolemur garnettii	87.90	0.00e+00	1276.00
IUUC-Oar-089576	Ovis aries	87.92	0.00e+00	1209.00
IUUC-Ptr-090507	Pan troglodytes	93.17	0.00e+00	1490.00
IUUC-Pan-092325	Papio anubis	88.49	0.00e+00	1433.00
IUUC-Psi-094021	Pelodiscus sinensis	85.23	0.00e+00	1394.00
IUUC-Pma-094372	Petromyzon marinus	52.37	0.00e+00	694.00
IUUC-Pfo-096732	Poecilia formosa	80.83	0.00e+00	1339.00
IUUC-Pab-098426	Pongo abelii	75.49	0.00e+00	1131.00
IUUC-Pca-100295	Procavia capensis	92.30	0.00e+00	1489.00
IUUC-Rno-105332	Rattus norvegicus	92.45	0.00e+00	1442.00
IUUC-Sha-106529	Sarcophilus harrisii	91.42	0.00e+00	1275.00
IUUC-Ssc-116176	Sus scrofa	92.78	0.00e+00	1445.00
IUUC-Tgu-116917	Taeniopygia guttata	88.53	0.00e+00	1391.00
IUUC-Tru-118398	Takifugu rubripes	79.27	0.00e+00	986.00
IUUC-Tni-120819	Tetraodon nigroviridis	78.79	0.00e+00	1190.00
IUUC-Xtr-132747	Xenopus tropicalis	77.51	0.00e+00	1263.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence