iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
iRefIndex	Mentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.50e-06	26.1	260	298

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCP 43
           C iCled+   d    lpC  ++h+ C+ +w         + +CP
   Q: 260  CVICLEDLspGDTIARLPCLCIYHKGCIDRW------FEVNRSCP 298
           *******977443777***************......66666677 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MGQKASTPAT SGQQSPRSRT FSSSSTGAAD SALQQQQHQH SNPGQNRGGN GGGGGGNDTT 60
GQGFNLLRTL PGLQVYHNQN STSIDRQRAR SLSSVPDIQQ QAQQQQQQGS ITSSGSSPHS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCCAATTGG ACTAACGCCT CTGTTGATAT CGAGAAACTC TTTTAATGTA ATGTATAAAA 60
AAAAATTAAA AAAAAATATG GAAAACGGTC ATTTAAATTG AGAGTGTAAT CAAGGCAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0016567--P:protein ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

dme:Dmel_CG14435

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002006	Ailuropoda melanoleuca	73.47	1.00e-40	156.00
IUUC-Apl-003883	Anas platyrhynchos	77.27	1.00e-41	159.00
IUUC-Aca-004497	Anolis carolinensis	73.47	6.00e-42	163.00
IUUC-Ath-006965	Arabidopsis thaliana	46.51	1.00e-09	57.00
IUUC-Acl-008261	Aspergillus clavatus	52.38	6.00e-10	58.20
IUUC-Afl-008724	Aspergillus flavus	52.38	2.00e-10	59.70
IUUC-Afu-008835	Aspergillus fumigatus	52.38	9.00e-10	57.80
IUUC-Ang-009666	Aspergillus niger	50.00	1.00e-09	57.40
IUUC-Ate-010331	Aspergillus terreus	31.58	4.00e-10	58.90
IUUC-Ame-011041	Astyanax mexicanus	67.68	2.00e-39	154.00
IUUC-Bta-013206	Bos taurus	73.47	3.00e-42	163.00
IUUC-Cel-018347	Caenorhabditis elegans	60.19	5.00e-34	136.00
IUUC-Cja-019912	Callithrix jacchus	73.47	9.00e-41	159.00
IUUC-Cfa-020388	Canis familiaris	52.87	3.00e-40	156.00
IUUC-Cpo-021584	Cavia porcellus	52.87	1.00e-40	158.00
IUUC-Csa-023094	Chlorocebus sabaeus	73.47	3.00e-41	160.00
IUUC-Cin-025162	Ciona intestinalis	55.75	5.00e-35	139.00
IUUC-Csv-026373	Ciona savignyi	55.26	2.00e-35	141.00
IUUC-Dre-027713	Danio rerio	65.42	4.00e-39	153.00
IUUC-Dno-029420	Dasypus novemcinctus	73.47	2.00e-41	161.00
IUUC-Dse-031322	Dothistroma septosporum	40.62	2.00e-09	57.00
IUUC-Eca-033414	Equus caballus	65.74	4.00e-39	151.00
IUUC-Fca-036570	Felis catus	52.87	2.00e-40	158.00
IUUC-Fal-037096	Ficedula albicollis	64.81	6.00e-38	148.00
IUUC-Fox-038020	Fusarium oxysporum	33.04	7.00e-10	58.20
IUUC-Fso-038176	Fusarium solani	44.07	3.00e-08	53.10
IUUC-Gmo-039148	Gadus morhua	53.10	6.00e-42	162.00
IUUC-Gga-041010	Gallus gallus	73.47	2.00e-41	160.00
IUUC-Gac-041711	Gasterosteus aculeatus	71.43	1.00e-39	155.00
IUUC-Hsa-046291	Homo sapiens	73.47	2.00e-41	161.00
IUUC-Itr-048339	Ictidomys tridecemlineatus	73.81	1.00e-37	146.00
IUUC-Lch-049870	Latimeria chalumnae	67.50	1.00e-28	118.00
IUUC-Loc-052877	Lepisosteus oculatus	72.45	5.00e-40	156.00
IUUC-Lma-053072	Leptosphaeria maculans	44.68	1.00e-08	53.90
IUUC-Laf-054451	Loxodonta africana	73.47	5.00e-41	159.00
IUUC-Mcc-055078	Macaca mulatta	73.47	3.00e-41	160.00
IUUC-Mga-059226	Meleagris gallopavo	73.81	2.00e-37	145.00
IUUC-Mmr-061658	Microcebus murinus	77.27	2.00e-41	158.00
IUUC-Mdo-062052	Monodelphis domestica	73.47	3.00e-41	160.00
IUUC-Mmu-063964	Mus musculus	73.47	4.00e-41	160.00
IUUC-Mpu-066334	Mustela putorius furo	52.87	2.00e-40	158.00
IUUC-Mlu-067491	Myotis lucifugus	66.36	7.00e-40	155.00
IUUC-Nfi-068593	Neosartorya fischeri	52.38	7.00e-10	58.20
IUUC-Nle-069306	Nomascus leucogenys	72.45	4.00e-39	153.00
IUUC-Ont-071907	Oreochromis niloticus	66.02	3.00e-38	150.00
IUUC-Oan-072941	Ornithorhynchus anatinus	63.10	4.00e-29	118.00
IUUC-Ocu-074256	Oryctolagus cuniculus	52.87	4.00e-40	157.00
IUUC-Ola-087551	Oryzias latipes	71.26	2.00e-37	145.00
IUUC-Oga-088009	Otolemur garnettii	73.47	2.00e-41	160.00
IUUC-Ptr-091609	Pan troglodytes	72.45	3.00e-41	160.00
IUUC-Pan-092598	Papio anubis	73.47	3.00e-41	160.00
IUUC-Psi-093749	Pelodiscus sinensis	78.57	4.00e-40	154.00
IUUC-Pma-094361	Petromyzon marinus	72.41	1.00e-38	149.00
IUUC-Pfo-096340	Poecilia formosa	64.76	2.00e-39	154.00
IUUC-Pab-097603	Pongo abelii	73.47	4.00e-41	160.00
IUUC-Pva-102216	Pteropus vampyrus	77.65	1.00e-38	152.00
IUUC-Pte-104063	Pyrenophora teres	39.34	4.00e-09	55.50
IUUC-Pyt-104423	Pyrenophora triticirepentis	39.34	4.00e-09	55.50
IUUC-Rno-104829	Rattus norvegicus	73.47	7.00e-41	159.00
IUUC-Ssl-108602	Sclerotinia sclerotiorum	42.62	1.00e-08	53.90
IUUC-Ssc-116023	Sus scrofa	77.27	3.00e-41	157.00
IUUC-Tgu-116682	Taeniopygia guttata	66.36	3.00e-39	153.00
IUUC-Tru-117571	Takifugu rubripes	69.39	2.00e-40	157.00
IUUC-Tni-120337	Tetraodon nigroviridis	67.35	1.00e-38	151.00
IUUC-Tvi-122664	Trichoderma virens	47.37	5.00e-08	52.00
IUUC-Tme-127002	Tuber melanosporum	51.85	1.00e-10	60.10
IUUC-Tbe-127983	Tupaia belangeri	73.47	8.00e-41	159.00
IUUC-Ttr-129090	Tursiops truncatus	73.47	1.00e-41	161.00
IUUC-Vda-129847	Verticillium dahliae	27.34	5.00e-08	51.60
IUUC-Xtr-132972	Xenopus tropicalis	69.15	2.00e-38	150.00
IUUC-Xma-133699	Xiphophorus maculatus	66.67	4.00e-40	155.00
IUUC-Yli-134502	Yarrowia lipolytica	39.58	8.00e-11	60.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence