iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037631

Ensembl Protein ID

ENSFALP00000002732.1

UniProt Accession

U3JIX8; U3JIX8_FICAL

Genbank Protein ID

ENSFALP00000002732

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01021290

Gene Name

KDM5B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000002622.1	ENSFALT00000002744.1	ENSFALP00000002732.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.20e-24	85.1	268	314

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vCl+Cg+g +++  l+ C+ C++ +H  Cl ++   ++p+ + w Cp+C 
   Q: 268  VCLLCGSGNDED-RLLLCDGCDDSYHTFCLIPP-LHDVPKGD-WRCPQCL 314
           8********988.6*******************.*******7.******5 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MCTPAWQESQ LEYVRFLNSL LHGSFSAQDW QPPFACDVDK LHFTPRIQRL NELEAQTRVK 60
LNFLDQIAKF WELQGCTLKI PHVERKILDL FQLNRLVAEQ GGFDVVCKER KWTKIATRMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATTATTCCA AGGGTTCAGA TATGAATATT GCCATCCTTC TGTGTAAGCT GATGAAACAG 60
GAGAGGGTTT GGCTAATCAG GTTTATCTTC AGATGTGAAC AGCCTCTGTC TGAAGCCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0010628--P:positive regulation of gene expression
GO:0033601--P:positive regulation of mammary gland epithelial cell proliferation
GO:0009791--P:post-embryonic development
GO:2000864--P:regulation of estradiol secretion
GO:0007338--P:single fertilization
GO:0061038--P:uterus morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000552	Aegilops tauschii	34.59	2.00e-97	351.00
IUUC-Aml-001963	Ailuropoda melanoleuca	83.32	0.00e+00	2380.00
IUUC-Apl-003770	Anas platyrhynchos	91.29	0.00e+00	2308.00
IUUC-Aca-004867	Anolis carolinensis	81.23	0.00e+00	2409.00
IUUC-Ame-010620	Astyanax mexicanus	61.40	0.00e+00	1800.00
IUUC-Bta-012733	Bos taurus	81.09	0.00e+00	2293.00
IUUC-Bci-013992	Botrytis cinerea	35.26	4.00e-107	383.00
IUUC-Bol-015336	Brassica oleracea	35.65	1.00e-14	76.30
IUUC-Cja-019050	Callithrix jacchus	82.64	0.00e+00	2384.00
IUUC-Cfa-021015	Canis familiaris	83.24	0.00e+00	2375.00
IUUC-Cpo-022340	Cavia porcellus	83.11	0.00e+00	2341.00
IUUC-Csa-023441	Chlorocebus sabaeus	82.97	0.00e+00	2365.00
IUUC-Cho-024823	Choloepus hoffmanni	88.55	0.00e+00	1466.00
IUUC-Cgl-026613	Colletotrichum gloeosporioides	30.69	4.00e-110	393.00
IUUC-Cne-026851	Cryptococcus neoformans	30.68	9.00e-111	395.00
IUUC-Dre-027707	Danio rerio	60.66	0.00e+00	1722.00
IUUC-Dno-028978	Dasypus novemcinctus	83.11	0.00e+00	2372.00
IUUC-Dor-030854	Dipodomys ordii	74.10	0.00e+00	1627.00
IUUC-Ete-032760	Echinops telfairi	79.47	0.00e+00	1617.00
IUUC-Eca-034370	Equus caballus	83.18	0.00e+00	2314.00
IUUC-Eeu-035012	Erinaceus europaeus	67.80	0.00e+00	1650.00
IUUC-Fca-035494	Felis catus	83.38	0.00e+00	2367.00
IUUC-Fox-037694	Fusarium oxysporum	32.04	1.00e-98	355.00
IUUC-Gmo-039522	Gadus morhua	66.64	0.00e+00	1503.00
IUUC-Ggr-039929	Gaeumannomyces graminis	33.20	2.00e-100	361.00
IUUC-Gga-040802	Gallus gallus	90.66	0.00e+00	2542.00
IUUC-Gac-041563	Gasterosteus aculeatus	60.36	0.00e+00	1738.00
IUUC-Gma-042675	Glycine max	33.69	1.00e-105	378.00
IUUC-Ggo-044856	Gorilla gorilla	67.83	0.00e+00	1796.00
IUUC-Hsa-045888	Homo sapiens	81.07	0.00e+00	2368.00
IUUC-Hvu-047583	Hordeum vulgare	43.04	1.00e-15	79.00
IUUC-Itr-048297	Ictidomys tridecemlineatus	83.31	0.00e+00	2353.00
IUUC-Lch-050483	Latimeria chalumnae	65.03	0.00e+00	1918.00
IUUC-Lpe-051537	Leersia perrieri	40.92	1.00e-89	325.00
IUUC-Loc-052550	Lepisosteus oculatus	69.87	0.00e+00	1993.00
IUUC-Laf-053761	Loxodonta africana	82.16	0.00e+00	2337.00
IUUC-Mcc-055505	Macaca mulatta	81.07	0.00e+00	2366.00
IUUC-Mpo-057317	Magnaporthe poae	33.47	4.00e-104	373.00
IUUC-Mga-059358	Meleagris gallopavo	91.70	0.00e+00	2536.00
IUUC-Mmr-060863	Microcebus murinus	82.85	0.00e+00	2346.00
IUUC-Mdo-061957	Monodelphis domestica	84.11	0.00e+00	2454.00
IUUC-Mmu-063944	Mus musculus	81.96	0.00e+00	2318.00
IUUC-Mac-065069	Musa acuminata	35.14	6.00e-08	54.30
IUUC-Mpu-066719	Mustela putorius furo	81.75	0.00e+00	2357.00
IUUC-Mlu-068086	Myotis lucifugus	78.80	0.00e+00	2225.00
IUUC-Nfi-068430	Neosartorya fischeri	29.84	1.00e-112	401.00
IUUC-Ncr-068763	Neurospora crassa	34.05	7.00e-107	382.00
IUUC-Nle-069256	Nomascus leucogenys	81.21	0.00e+00	2373.00
IUUC-Opr-071002	Ochotona princeps	51.19	0.00e+00	1215.00
IUUC-Ont-071756	Oreochromis niloticus	60.92	0.00e+00	1766.00
IUUC-Oan-073568	Ornithorhynchus anatinus	85.63	0.00e+00	2447.00
IUUC-Ocu-073961	Oryctolagus cuniculus	81.49	0.00e+00	2320.00
IUUC-Ogl-077886	Oryza glaberrima	38.83	2.00e-16	80.90
IUUC-Oin-079273	Oryza indica	50.00	2.00e-13	68.20
IUUC-Olo-080668	Oryza longistaminata	38.83	7.00e-16	80.50
IUUC-Opu-083164	Oryza punctata	39.82	3.00e-86	313.00
IUUC-Osa-085487	Oryza sativa	38.83	2.00e-16	81.30
IUUC-Ola-086448	Oryzias latipes	59.63	0.00e+00	1721.00
IUUC-Oga-088501	Otolemur garnettii	79.04	0.00e+00	2013.00
IUUC-Oar-090162	Ovis aries	80.43	0.00e+00	2286.00
IUUC-Ptr-090816	Pan troglodytes	81.27	0.00e+00	2375.00
IUUC-Pan-092764	Papio anubis	83.04	0.00e+00	2367.00
IUUC-Psi-093918	Pelodiscus sinensis	85.07	0.00e+00	2270.00
IUUC-Ppa-095839	Physcomitrella patens	53.45	1.00e-15	79.70
IUUC-Pfo-096777	Poecilia formosa	63.64	0.00e+00	1724.00
IUUC-Pab-097854	Pongo abelii	83.14	0.00e+00	1878.00
IUUC-Pca-100241	Procavia capensis	77.58	0.00e+00	1499.00
IUUC-Ppe-101504	Prunus persica	33.37	6.00e-105	375.00
IUUC-Pva-103035	Pteropus vampyrus	77.60	0.00e+00	1981.00
IUUC-Rno-105574	Rattus norvegicus	80.63	0.00e+00	2275.00
IUUC-Sce-106207	Saccharomyces cerevisiae	36.71	3.00e-74	273.00
IUUC-Sly-111298	Solanum lycopersicum	42.66	6.00e-102	366.00
IUUC-Sar-113477	Sorex araneus	80.62	0.00e+00	2139.00
IUUC-Ssc-116132	Sus scrofa	84.02	0.00e+00	2095.00
IUUC-Tgu-117452	Taeniopygia guttata	96.21	0.00e+00	2775.00
IUUC-Tru-117561	Takifugu rubripes	62.29	0.00e+00	1616.00
IUUC-Tsy-119271	Tarsius syrichta	81.67	0.00e+00	1863.00
IUUC-Tni-119650	Tetraodon nigroviridis	64.49	0.00e+00	1644.00
IUUC-Tca-121478	Theobroma cacao	42.34	2.00e-103	371.00
IUUC-Tae-125894	Triticum aestivum	31.72	3.00e-99	357.00
IUUC-Tur-126632	Triticum urartu	35.03	5.00e-98	352.00
IUUC-Tbe-127890	Tupaia belangeri	74.31	0.00e+00	1255.00
IUUC-Ttr-128546	Tursiops truncatus	80.69	0.00e+00	1734.00
IUUC-Vpa-130432	Vicugna pacos	78.92	0.00e+00	1380.00
IUUC-Vvi-131071	Vitis vinifera	31.28	2.00e-83	304.00
IUUC-Xtr-132008	Xenopus tropicalis	70.28	0.00e+00	2046.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence