iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000040688.16	ENSMUST00000126319.7	ENSMUSP00000120911.1
ENSMUSG00000040688.16	ENSMUST00000130633.1	ENSMUSP00000117818.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	HINT
Mentha
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-51	171.3	108	138
UBD/Beta-Prp	7.40e-97	325.3	413	646

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDl 30
           Ht++v ++af  ++tll++G+ Dg ++vWD+
   Q: 108  HTAPVASMAFdaTSTLLATGGCDGAVRVWDI 138
           9*********9755****************7 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls...............tgkcvhtlkghedsvlslsfspsgdklvsGshdr 116
           ++++ sgh+  v ++++s+ ++ +lvtgs+D t+k+w+l                  +   t + h++++ sl++sp+++ l++Gs+dr
   Q: 413  CVAQGSGHTHSVGTICCSRLKEsFLVTGSQDCTVKLWPLPeallakstaadsgpvLLQAQTTRRCHDKDINSLAVSPNDKLLATGSQDR 501
           678889***********998778**************7777788888888865554444445558************************ PP
   S: 117  tirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvk 205
           t+++w l++ q l  +++gh++  + v+++p++++l+++s+D+t++lW l+  ++l+t++g h+ sv +++f s g +l+s + dg +k
   Q: 502  TAKLWALPQCQLLG-VFTGHRRGLWNVQFSPTDQVLATASADGTIKLWALQDFSCLKTFEG-HDASVLKVAFVSRGSQLLSSGSDGLLK 588
           *************9.*********************************************9.*************************** PP
   S: 206  lwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW.dlrsgdllktlql 262
           lw ++++ecvrtl +h+d v+ ++ s+ d++ ++g+sD  i +W d++  +     ++
   Q: 589  LWTIKSNECVRTLDAHEDKVWGLHCSQLDDHAITGGSDSRIILWkDVTEAEQAEEQAK 646
           ********************************************88777666555555 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MAETAAGLCR FKANYAVERK IEPFYKGGKA QLDQTGHYLF CVCGTKVNIL DVASGALLRS 60
LEQEDQEDIT SFDLSPDDEV LVTASRALLL AQWAWREGTV TRLWKAIHTA PVASMAFDAT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGACGTCATC ACCGCGTGCC TTGAAGTACA GAGTAGCACA CTGGCCGGTT CACGCGGGGA 60
GAAAGGCTGC TGAACTTGGA GGCGCTGCCC TGGGACATGG CCGAGACTGC GGCGGGATTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR013934--SSU_processome_Utp13
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08625--Utp13
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0003723--F:RNA binding
GO:0030515--F:snoRNA binding
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

KEGG

mmu:213773

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000765	Aegilops tauschii	36.00	3.00e-146	512.00
IUUC-Aml-002376	Ailuropoda melanoleuca	87.15	0.00e+00	1376.00
IUUC-Atr-002486	Amborella trichopoda	39.51	8.00e-164	571.00
IUUC-Apl-003519	Anas platyrhynchos	61.70	0.00e+00	898.00
IUUC-Aca-004363	Anolis carolinensis	55.78	6.00e-148	517.00
IUUC-Aly-006152	Arabidopsis lyrata	35.21	2.00e-149	523.00
IUUC-Ath-006966	Arabidopsis thaliana	35.17	3.00e-147	516.00
IUUC-Ago-007746	Ashbya gossypii	30.56	2.00e-105	376.00
IUUC-Acl-008009	Aspergillus clavatus	29.82	4.00e-104	372.00
IUUC-Afl-008681	Aspergillus flavus	29.67	1.00e-96	347.00
IUUC-Afu-008798	Aspergillus fumigatus	28.94	1.00e-93	337.00
IUUC-Ani-009278	Aspergillus nidulans	28.53	4.00e-99	356.00
IUUC-Ang-009640	Aspergillus niger	30.14	4.00e-102	366.00
IUUC-Aor-010160	Aspergillus oryzae	29.67	2.00e-96	347.00
IUUC-Ate-010320	Aspergillus terreus	29.13	2.00e-104	373.00
IUUC-Ame-010930	Astyanax mexicanus	60.78	1.00e-75	275.00
IUUC-Bgr-012054	Blumeria graminis	28.54	9.00e-104	371.00
IUUC-Bta-012611	Bos taurus	88.21	0.00e+00	1372.00
IUUC-Bci-013797	Botrytis cinerea	30.51	2.00e-111	397.00
IUUC-Bdi-014384	Brachypodium distachyon	39.07	1.00e-164	573.00
IUUC-Bol-015097	Brassica oleracea	35.95	2.00e-148	520.00
IUUC-Bra-017798	Brassica rapa	35.71	1.00e-149	523.00
IUUC-Cel-018664	Caenorhabditis elegans	31.63	5.00e-123	435.00
IUUC-Cja-019092	Callithrix jacchus	88.73	0.00e+00	1421.00
IUUC-Cfa-021040	Canis familiaris	87.12	0.00e+00	1369.00
IUUC-Cpo-022529	Cavia porcellus	89.89	0.00e+00	1405.00
IUUC-Cre-022986	Chlamydomonas reinhardtii	58.02	8.00e-45	172.00
IUUC-Csa-024205	Chlorocebus sabaeus	89.24	0.00e+00	1433.00
IUUC-Cin-025560	Ciona intestinalis	45.39	0.00e+00	717.00
IUUC-Cgl-026481	Colletotrichum gloeosporioides	31.40	8.00e-115	408.00
IUUC-Cne-027082	Cryptococcus neoformans	29.35	2.00e-112	400.00
IUUC-Cme-027159	Cyanidioschyzon merolae	25.31	1.00e-31	132.00
IUUC-Dre-028138	Danio rerio	52.81	0.00e+00	876.00
IUUC-Dno-029914	Dasypus novemcinctus	64.96	0.00e+00	799.00
IUUC-Dor-030685	Dipodomys ordii	76.71	0.00e+00	909.00
IUUC-Dse-031429	Dothistroma septosporum	29.44	6.00e-100	358.00
IUUC-Dme-031995	Drosophila melanogaster	31.58	1.00e-117	417.00
IUUC-Ete-033086	Echinops telfairi	89.61	0.00e+00	778.00
IUUC-Eca-034354	Equus caballus	90.64	0.00e+00	1394.00
IUUC-Eeu-034832	Erinaceus europaeus	87.58	0.00e+00	799.00
IUUC-Fca-036136	Felis catus	83.42	0.00e+00	1298.00
IUUC-Fal-036859	Ficedula albicollis	65.44	0.00e+00	1048.00
IUUC-Fox-037863	Fusarium oxysporum	30.81	3.00e-100	359.00
IUUC-Fso-038389	Fusarium solani	31.03	2.00e-113	403.00
IUUC-Gmo-038711	Gadus morhua	57.55	0.00e+00	894.00
IUUC-Ggr-039820	Gaeumannomyces graminis	28.48	4.00e-102	365.00
IUUC-Gga-040263	Gallus gallus	66.46	0.00e+00	1093.00
IUUC-Gac-041291	Gasterosteus aculeatus	61.72	0.00e+00	1024.00
IUUC-Gma-044026	Glycine max	38.31	3.00e-164	572.00
IUUC-Ggo-044693	Gorilla gorilla	89.49	0.00e+00	1400.00
IUUC-Hsa-046048	Homo sapiens	89.75	0.00e+00	1406.00
IUUC-Hvu-047608	Hordeum vulgare	38.16	2.00e-163	570.00
IUUC-Itr-048391	Ictidomys tridecemlineatus	89.61	0.00e+00	1446.00
IUUC-Kpa-049209	Komagataella pastoris	32.15	1.00e-117	417.00
IUUC-Lch-050085	Latimeria chalumnae	62.64	0.00e+00	997.00
IUUC-Lpe-050945	Leersia perrieri	38.68	2.00e-161	563.00
IUUC-Loc-052679	Lepisosteus oculatus	64.17	0.00e+00	1070.00
IUUC-Laf-053685	Loxodonta africana	86.31	0.00e+00	1328.00
IUUC-Mcc-055861	Macaca mulatta	89.24	0.00e+00	1402.00
IUUC-Meu-056820	Macropus eugenii	69.68	0.00e+00	939.00
IUUC-Mor-057234	Magnaporthe oryzae	28.80	9.00e-101	361.00
IUUC-Mpo-057456	Magnaporthe poae	30.45	2.00e-84	306.00
IUUC-Mtr-058122	Medicago truncatula	38.80	1.00e-166	580.00
IUUC-Mla-058980	Melampsora laricipopulina	28.44	2.00e-93	337.00
IUUC-Mga-060080	Meleagris gallopavo	65.34	0.00e+00	1078.00
IUUC-Mvi-060338	Microbotryum violaceum	35.68	9.00e-143	501.00
IUUC-Mmr-060762	Microcebus murinus	89.62	0.00e+00	1385.00
IUUC-Mdo-061975	Monodelphis domestica	73.62	0.00e+00	1130.00
IUUC-Mac-065189	Musa acuminata	36.10	1.00e-157	550.00
IUUC-Mpu-066526	Mustela putorius furo	87.33	0.00e+00	1368.00
IUUC-Mlu-067716	Myotis lucifugus	88.73	0.00e+00	1456.00
IUUC-Nfi-068474	Neosartorya fischeri	29.56	3.00e-97	349.00
IUUC-Ncr-068826	Neurospora crassa	28.31	2.00e-95	344.00
IUUC-Nle-069832	Nomascus leucogenys	89.62	0.00e+00	1435.00
IUUC-Opr-071183	Ochotona princeps	80.63	0.00e+00	1273.00
IUUC-Ont-072371	Oreochromis niloticus	62.91	0.00e+00	1020.00
IUUC-Oan-073491	Ornithorhynchus anatinus	65.58	0.00e+00	922.00
IUUC-Oba-075963	Oryza barthii	37.96	1.00e-162	567.00
IUUC-Obr-076173	Oryza brachyantha	39.15	4.00e-162	565.00
IUUC-Ogl-077692	Oryza glaberrima	37.96	3.00e-162	565.00
IUUC-Ogu-078965	Oryza glumaepatula	37.96	1.00e-162	566.00
IUUC-Oin-079708	Oryza indica	37.96	6.00e-163	568.00
IUUC-Olo-080679	Oryza longistaminata	37.42	5.00e-159	555.00
IUUC-Oni-082960	Oryza nivara	37.83	1.00e-162	566.00
IUUC-Opu-083282	Oryza punctata	37.53	1.00e-155	544.00
IUUC-Oru-085224	Oryza rufipogon	37.96	8.00e-163	567.00
IUUC-Osa-085320	Oryza sativa	37.96	8.00e-163	567.00
IUUC-Ola-086370	Oryzias latipes	47.88	5.00e-131	461.00
IUUC-Olu-087814	Ostreococcus lucimarinus	32.33	1.00e-101	365.00
IUUC-Oga-088458	Otolemur garnettii	87.97	0.00e+00	1452.00
IUUC-Oar-090032	Ovis aries	80.69	0.00e+00	971.00
IUUC-Ptr-090749	Pan troglodytes	89.49	0.00e+00	1399.00
IUUC-Pan-091691	Papio anubis	86.33	0.00e+00	1342.00
IUUC-Psi-093200	Pelodiscus sinensis	65.19	0.00e+00	1060.00
IUUC-Pma-094165	Petromyzon marinus	52.13	0.00e+00	641.00
IUUC-Pno-095048	Phaeosphaeria nodorum	31.70	4.00e-90	325.00
IUUC-Ppa-095336	Physcomitrella patens	40.47	3.00e-160	559.00
IUUC-Pfo-096132	Poecilia formosa	62.33	0.00e+00	985.00
IUUC-Pab-097855	Pongo abelii	89.11	0.00e+00	1425.00
IUUC-Pop-099434	Populus trichocarpa	36.29	2.00e-153	536.00
IUUC-Pca-100232	Procavia capensis	83.59	2.00e-165	576.00
IUUC-Ppe-101665	Prunus persica	36.08	4.00e-156	545.00
IUUC-Pva-102178	Pteropus vampyrus	88.31	0.00e+00	1396.00
IUUC-Pgr-103288	Puccinia graminis	31.28	7.00e-82	298.00
IUUC-Ptt-103808	Puccinia triticina	32.38	3.00e-85	309.00
IUUC-Pte-104205	Pyrenophora teres	31.24	1.00e-106	381.00
IUUC-Pyt-104658	Pyrenophora triticirepentis	30.22	4.00e-97	349.00
IUUC-Rno-105617	Rattus norvegicus	95.56	0.00e+00	1488.00
IUUC-Sce-106281	Saccharomyces cerevisiae	31.04	5.00e-111	395.00
IUUC-Sha-107378	Sarcophilus harrisii	73.72	0.00e+00	1134.00
IUUC-Sja-107718	Schizosaccharomyces japonicus	33.92	2.00e-120	426.00
IUUC-Spo-108361	Schizosaccharomyces pombe	32.92	1.00e-114	407.00
IUUC-Ssl-108592	Sclerotinia sclerotiorum	30.74	3.00e-115	409.00
IUUC-Smo-109257	Selaginella moellendorffii	39.08	3.00e-159	555.00
IUUC-Sit-110258	Setaria italica	36.99	3.00e-164	572.00
IUUC-Sly-111521	Solanum lycopersicum	37.44	4.00e-156	545.00
IUUC-Stu-112718	Solanum tuberosum	45.71	1.00e-33	135.00
IUUC-Sar-113586	Sorex araneus	74.01	1.00e-62	234.00
IUUC-Sbi-114768	Sorghum bicolor	38.07	1.00e-167	583.00
IUUC-Sre-115159	Sporisorium reilianum	33.58	2.00e-94	340.00
IUUC-Ssc-116342	Sus scrofa	66.96	0.00e+00	925.00
IUUC-Tgu-117320	Taeniopygia guttata	64.24	0.00e+00	1014.00
IUUC-Tru-118024	Takifugu rubripes	61.55	0.00e+00	979.00
IUUC-Tni-119971	Tetraodon nigroviridis	62.10	0.00e+00	987.00
IUUC-Tca-121248	Theobroma cacao	37.52	4.00e-160	558.00
IUUC-Tre-122079	Trichoderma reesei	30.56	2.00e-103	370.00
IUUC-Tvi-122554	Trichoderma virens	30.16	4.00e-103	369.00
IUUC-Tae-123552	Triticum aestivum	38.80	3.00e-166	578.00
IUUC-Tur-126436	Triticum urartu	37.24	2.00e-133	469.00
IUUC-Tme-126942	Tuber melanosporum	31.26	7.00e-108	385.00
IUUC-Tbe-128000	Tupaia belangeri	88.20	7.00e-85	308.00
IUUC-Ttr-128964	Tursiops truncatus	86.82	0.00e+00	1385.00
IUUC-Uma-129473	Ustilago maydis	32.46	3.00e-103	370.00
IUUC-Vda-129749	Verticillium dahliae	30.05	8.00e-97	348.00
IUUC-Vvi-131511	Vitis vinifera	38.30	3.00e-160	559.00
IUUC-Xtr-132816	Xenopus tropicalis	56.91	0.00e+00	902.00
IUUC-Xma-133672	Xiphophorus maculatus	62.45	0.00e+00	1021.00
IUUC-Yli-134602	Yarrowia lipolytica	35.49	2.00e-139	489.00
IUUC-Zma-135976	Zea mays	36.92	2.00e-157	550.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence