iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035955

Ensembl Protein ID

ENSFCAP00000005843.2

UniProt Accession

M3W5M1; M3W5M1_FELCA

Genbank Protein ID

ENSFCAP00000005843

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02047998

Gene Name

CRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000006290.2	ENSFCAT00000006292.2	ENSFCAP00000005843.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.80e-19	67.6	55	110

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            e+v++l+d++++++++L +kkGd++++   ++ +e W+++ ++ egkrG++P  +vek
   Q: 55   AEYVRALFDFNGNDEEDLPFKKGDILRI--RDKPEEQWWNA-EDSEGKRGMIPVPYVEK 110
           689*************************..6999******9.5**************98 PP

Organism

Felis catus

Protein Sequence
(Fasta)

PGVSPSRLRI GDQEFDSLPA LLEFYKIHYL DTTTLIEPVS KSRQGSGVIL RQEEAEYVRA 60
LFDFNGNDEE DLPFKKGDIL RIRDKPEEQW WNAEDSEGKR GMIPVPYVEK YRPASASVSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGGGGTGA GCCCCTCCAG ACTCCGAATA GGAGATCAAG AGTTTGATTC ATTGCCTGCT 60
TTACTGGAAT TCTACAAAAT ACATTATTTG GACACTACAA CGTTGATAGA ACCAGTTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0048013--P:ephrin receptor signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001192	Ailuropoda melanoleuca	99.54	8.00e-128	449.00
IUUC-Apl-003225	Anas platyrhynchos	91.56	1.00e-121	428.00
IUUC-Aca-004818	Anolis carolinensis	78.79	7.00e-93	332.00
IUUC-Bta-012320	Bos taurus	99.54	9.00e-128	449.00
IUUC-Cja-019935	Callithrix jacchus	99.11	4.00e-131	460.00
IUUC-Cfa-021221	Canis familiaris	99.54	2.00e-127	449.00
IUUC-Cpo-021592	Cavia porcellus	98.22	6.00e-130	456.00
IUUC-Cho-024775	Choloepus hoffmanni	98.63	6.00e-128	449.00
IUUC-Dno-029847	Dasypus novemcinctus	99.54	9.00e-128	449.00
IUUC-Dor-030360	Dipodomys ordii	98.21	6.00e-127	446.00
IUUC-Ete-032604	Echinops telfairi	96.41	4.00e-125	440.00
IUUC-Eca-033233	Equus caballus	98.66	2.00e-130	457.00
IUUC-Eeu-034642	Erinaceus europaeus	96.86	5.00e-127	446.00
IUUC-Fal-037152	Ficedula albicollis	93.33	2.00e-125	441.00
IUUC-Gga-040731	Gallus gallus	90.99	9.00e-122	429.00
IUUC-Ggo-045475	Gorilla gorilla	99.54	9.00e-128	449.00
IUUC-Hsa-046008	Homo sapiens	99.54	9.00e-128	449.00
IUUC-Itr-048906	Ictidomys tridecemlineatus	98.86	3.00e-98	350.00
IUUC-Lch-050509	Latimeria chalumnae	86.03	1.00e-116	412.00
IUUC-Laf-053896	Loxodonta africana	99.56	7.00e-132	462.00
IUUC-Mcc-055280	Macaca mulatta	99.54	9.00e-128	449.00
IUUC-Meu-056783	Macropus eugenii	96.41	6.00e-126	442.00
IUUC-Mga-059345	Meleagris gallopavo	91.93	6.00e-123	432.00
IUUC-Mdo-062691	Monodelphis domestica	95.09	1.00e-123	436.00
IUUC-Mmu-063691	Mus musculus	99.08	2.00e-127	448.00
IUUC-Mpu-065737	Mustela putorius furo	99.54	9.00e-128	449.00
IUUC-Mlu-067005	Myotis lucifugus	95.87	2.00e-123	434.00
IUUC-Nle-070154	Nomascus leucogenys	99.11	8.00e-131	458.00
IUUC-Opr-071114	Ochotona princeps	98.66	1.00e-129	455.00
IUUC-Oan-072967	Ornithorhynchus anatinus	96.65	1.00e-98	352.00
IUUC-Olo-080293	Oryza longistaminata	40.00	2.00e+00	25.80
IUUC-Oga-088266	Otolemur garnettii	98.62	5.00e-127	446.00
IUUC-Oar-089221	Ovis aries	99.08	2.00e-127	448.00
IUUC-Ptr-091463	Pan troglodytes	99.54	2.00e-127	447.00
IUUC-Pan-092242	Papio anubis	99.54	9.00e-128	449.00
IUUC-Psi-093287	Pelodiscus sinensis	95.09	2.00e-126	444.00
IUUC-Pab-097823	Pongo abelii	99.15	3.00e-65	241.00
IUUC-Pca-101068	Procavia capensis	99.54	9.00e-128	449.00
IUUC-Ptt-103815	Puccinia triticina	37.93	3.00e-09	55.80
IUUC-Rno-105288	Rattus norvegicus	99.08	3.00e-127	447.00
IUUC-Sar-113453	Sorex araneus	96.86	5.00e-126	443.00
IUUC-Tgu-116926	Taeniopygia guttata	91.44	4.00e-120	423.00
IUUC-Tbe-127436	Tupaia belangeri	92.66	7.00e-109	386.00
IUUC-Ttr-129109	Tursiops truncatus	99.55	4.00e-130	456.00
IUUC-Vpa-130527	Vicugna pacos	99.08	1.00e-125	442.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence