iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cja-018716

Ensembl Protein ID

ENSCJAP00000014513.2

UniProt Accession

F7IL46; F7IL46_CALJA

Genbank Protein ID

JAB11213.1; JAB22402.1; JAB32327.1; JAB51321.1

Protein Name

Putative ATP-dependent RNA helicase DDX58

Genbank Nucleotide ID

ACFV01033622; GAMS01000734; GAMR01001605; GAMP01001434

Gene Name

DDX58

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000007741.2	ENSCJAT00000015255.1	ENSCJAP00000014472.1
ENSCJAG00000007741.2	ENSCJAT00000015302.2	ENSCJAP00000014513.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	2.30e-53	179.6	101	172

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 3    eeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL..vqkegWfrefl 73
           eeyrlll++lq++++ ++++td+l  +lse+l+++e+e+i+++++tkg+m++ae+L+++L  ++ke+W+++++
   Q: 101  EEYRLLLKRLQPEFKSRIIPTDILP-DLSECLINQECEEIIQICSTKGMMAGAEKLVECLlrSDKENWPKTLK 172
           9************************.********************************************985 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MTVEQRSSLR AFRDYIRKTL DPTYIMSYMA PWLREEEMQY IQAEKNNKGP VEAATLFLKI 60
LLELQEEGWF RGFLDALDHA GYSGLYEAIE SWDFQKIEKL EEYRLLLKRL QPEFKSRIIP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAAAGTTCCT CGCAGCTCCG CCTCTCGTCC GGTATCATTT CTCCGGAAAA TCCCTGCTTT 60
CCCCGCTCGC CACGCCCTCC TCCTCCAGCC CGGCTTTAAA GTCAGTGAGG TGCAGCTGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0347--Helicase
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR003593--AAA+_ATPase
IPR031964--CARD_dom
IPR011545--DEAD/DEAH_box_helicase_dom
IPR011029--DEATH-like_dom
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00270--DEAD
PF00271--Helicase_C
PF11648--RIG-I_C-RD

SMART

SM00382--AAA
SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005923--C:bicellular tight junction
GO:0005829--C:cytosol
GO:0032587--C:ruffle membrane
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0004386--F:helicase activity
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0009597--P:detection of virus
GO:0045087--P:innate immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0032725--P:positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030334--P:regulation of cell migration
GO:0043330--P:response to exogenous dsRNA
GO:0039529--P:RIG-I signaling pathway

KEGG

cjc:100408692

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001898	Ailuropoda melanoleuca	78.52	0.00e+00	1477.00
IUUC-Apl-003966	Anas platyrhynchos	53.94	0.00e+00	912.00
IUUC-Aca-004499	Anolis carolinensis	46.83	0.00e+00	812.00
IUUC-Ame-011950	Astyanax mexicanus	44.44	0.00e+00	697.00
IUUC-Bta-012489	Bos taurus	79.25	0.00e+00	1440.00
IUUC-Cel-018230	Caenorhabditis elegans	29.16	4.00e-71	263.00
IUUC-Cfa-020269	Canis familiaris	80.95	0.00e+00	1527.00
IUUC-Cpo-022507	Cavia porcellus	76.72	0.00e+00	1436.00
IUUC-Csa-024209	Chlorocebus sabaeus	93.08	0.00e+00	1745.00
IUUC-Cho-025104	Choloepus hoffmanni	74.11	0.00e+00	1184.00
IUUC-Cin-025792	Ciona intestinalis	31.47	2.00e-74	273.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	25.05	4.00e-22	100.00
IUUC-Dno-028954	Dasypus novemcinctus	78.54	0.00e+00	1429.00
IUUC-Eca-034039	Equus caballus	81.30	0.00e+00	1521.00
IUUC-Eeu-035009	Erinaceus europaeus	69.10	0.00e+00	917.00
IUUC-Fca-036169	Felis catus	81.10	0.00e+00	1542.00
IUUC-Fal-037579	Ficedula albicollis	54.71	0.00e+00	921.00
IUUC-Ggo-045318	Gorilla gorilla	90.92	0.00e+00	1576.00
IUUC-Hsa-046671	Homo sapiens	94.27	0.00e+00	1728.00
IUUC-Itr-047996	Ictidomys tridecemlineatus	78.11	0.00e+00	1440.00
IUUC-Lch-050461	Latimeria chalumnae	51.35	0.00e+00	870.00
IUUC-Loc-052582	Lepisosteus oculatus	48.07	0.00e+00	842.00
IUUC-Laf-054324	Loxodonta africana	78.69	0.00e+00	1440.00
IUUC-Mcc-055390	Macaca mulatta	92.76	0.00e+00	1733.00
IUUC-Meu-056365	Macropus eugenii	55.59	4.00e-179	621.00
IUUC-Mor-057000	Magnaporthe oryzae	28.26	2.50e-01	31.60
IUUC-Mpo-057328	Magnaporthe poae	22.22	1.70e-01	32.00
IUUC-Mmr-061407	Microcebus murinus	84.34	0.00e+00	1608.00
IUUC-Mmu-063939	Mus musculus	76.54	0.00e+00	1415.00
IUUC-Mpu-066226	Mustela putorius furo	78.14	0.00e+00	1395.00
IUUC-Mlu-068092	Myotis lucifugus	80.13	0.00e+00	1449.00
IUUC-Nfi-068405	Neosartorya fischeri	24.91	2.00e-25	111.00
IUUC-Opr-070246	Ochotona princeps	69.12	0.00e+00	689.00
IUUC-Oan-072742	Ornithorhynchus anatinus	61.94	0.00e+00	973.00
IUUC-Ocu-073959	Oryctolagus cuniculus	75.92	0.00e+00	1444.00
IUUC-Oga-089173	Otolemur garnettii	83.80	0.00e+00	1558.00
IUUC-Oar-089369	Ovis aries	78.71	0.00e+00	1402.00
IUUC-Ptr-091032	Pan troglodytes	94.27	0.00e+00	1728.00
IUUC-Pan-092383	Papio anubis	92.76	0.00e+00	1729.00
IUUC-Psi-093432	Pelodiscus sinensis	57.00	0.00e+00	1063.00
IUUC-Pma-094367	Petromyzon marinus	42.31	3.00e-115	408.00
IUUC-Pab-098416	Pongo abelii	93.83	0.00e+00	1613.00
IUUC-Pca-101006	Procavia capensis	77.47	0.00e+00	632.00
IUUC-Pva-102966	Pteropus vampyrus	82.58	0.00e+00	1533.00
IUUC-Pgr-103529	Puccinia graminis	26.01	5.00e-29	123.00
IUUC-Rno-105059	Rattus norvegicus	76.52	0.00e+00	916.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	28.57	7.00e-05	44.30
IUUC-Sar-113202	Sorex araneus	68.02	0.00e+00	1039.00
IUUC-Ssc-116120	Sus scrofa	77.96	0.00e+00	1413.00
IUUC-Tgu-117314	Taeniopygia guttata	53.22	0.00e+00	940.00
IUUC-Tsy-119453	Tarsius syrichta	84.64	0.00e+00	897.00
IUUC-Tre-122194	Trichoderma reesei	26.69	1.00e-19	92.80
IUUC-Ttr-128421	Tursiops truncatus	77.17	0.00e+00	1202.00
IUUC-Vpa-130602	Vicugna pacos	77.75	0.00e+00	1384.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence