iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004958

UUCD1 version

UUC-AnC-00735

Ensembl Protein ID

ENSACAP00000012100.3

UniProt Accession

G1KM60; G1KM60_ANOCA

Protein Name

Uncharacterized protein

Gene Name

KLHL8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000012252.3	ENSACAT00000012345.3	ENSACAP00000012100.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	7.50e-08	32.6	63	128
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	4.10e-09	35.6	162	192

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg + ++   +  + + s +  +fl+e  e k ++ +eikd + ++ ++l+kF+Y+++l++
   Q: 63   CDVTLKVGSKLISLSQACACLCYSLLPTMFLSEIAEAK-QSLIEIKDFDGDAIEDLVKFVYSSRLTL 128
           9************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Ncl++++fA+ ++  dL+d a+++++ hF
   Q: 162  PSNCLAVRAFAESHNRVDLMDMADRYACEHF 192
           89****************************9 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MASDCMVPEQ AKHRVVKGKR QQQYERSPLN SDAEEETFVF EANEAWKDFH SSLLHFYEAG 60
ELCDVTLKVG SKLISLSQAC ACLCYSLLPT MFLSEIAEAK QSLIEIKDFD GDAIEDLVKF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGGAAAGA AGCATGTATC TTATTCTCAC CGCCATCTCC AGCTCATGCC TTACCATCAT 60
CCTTGATACT GACAAGTTGC ACCCAAATGC ACTACTGTGG CTTCCTTGGC TAAGGAGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	85.16	0.00e+00	1085.00
IUUC-Atr-002726	Amborella trichopoda	36.89	5.00e-42	166.00
IUUC-Apl-003978	Anas platyrhynchos	87.06	0.00e+00	1125.00
IUUC-Ame-011139	Astyanax mexicanus	79.42	0.00e+00	1022.00
IUUC-Bta-013142	Bos taurus	86.73	0.00e+00	1097.00
IUUC-Cel-018551	Caenorhabditis elegans	37.90	7.00e-121	427.00
IUUC-Cja-019650	Callithrix jacchus	84.86	0.00e+00	1111.00
IUUC-Cfa-021046	Canis familiaris	85.78	0.00e+00	1090.00
IUUC-Cpo-022445	Cavia porcellus	85.16	0.00e+00	1048.00
IUUC-Csa-023642	Chlorocebus sabaeus	85.35	0.00e+00	1117.00
IUUC-Cho-025012	Choloepus hoffmanni	71.11	0.00e+00	793.00
IUUC-Dre-027723	Danio rerio	77.32	0.00e+00	1004.00
IUUC-Dno-028964	Dasypus novemcinctus	84.31	0.00e+00	903.00
IUUC-Dor-030899	Dipodomys ordii	77.56	1.00e-127	449.00
IUUC-Ete-032815	Echinops telfairi	83.39	0.00e+00	1075.00
IUUC-Eca-034162	Equus caballus	85.81	0.00e+00	1075.00
IUUC-Eeu-034660	Erinaceus europaeus	85.14	0.00e+00	1074.00
IUUC-Fca-035659	Felis catus	85.48	0.00e+00	1090.00
IUUC-Fal-037619	Ficedula albicollis	87.52	0.00e+00	1138.00
IUUC-Gmo-038546	Gadus morhua	81.24	0.00e+00	997.00
IUUC-Ggr-040041	Gaeumannomyces graminis	32.65	6.00e-09	54.70
IUUC-Gga-040770	Gallus gallus	87.54	0.00e+00	1104.00
IUUC-Gac-042557	Gasterosteus aculeatus	76.34	0.00e+00	991.00
IUUC-Ggo-044741	Gorilla gorilla	85.35	0.00e+00	1117.00
IUUC-Hsa-046025	Homo sapiens	85.35	0.00e+00	1117.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	89.45	0.00e+00	1009.00
IUUC-Loc-052834	Lepisosteus oculatus	81.52	0.00e+00	976.00
IUUC-Laf-054513	Loxodonta africana	85.00	0.00e+00	1097.00
IUUC-Mcc-054707	Macaca mulatta	85.19	0.00e+00	1113.00
IUUC-Meu-056779	Macropus eugenii	85.87	0.00e+00	1107.00
IUUC-Mga-059676	Meleagris gallopavo	87.38	0.00e+00	1103.00
IUUC-Mmr-061359	Microcebus murinus	84.86	0.00e+00	1078.00
IUUC-Mdo-062527	Monodelphis domestica	85.42	0.00e+00	1102.00
IUUC-Mmu-063112	Mus musculus	83.17	0.00e+00	1085.00
IUUC-Mpu-065800	Mustela putorius furo	84.68	0.00e+00	1079.00
IUUC-Mlu-067536	Myotis lucifugus	84.55	0.00e+00	1050.00
IUUC-Nle-069397	Nomascus leucogenys	85.35	0.00e+00	1117.00
IUUC-Opr-070599	Ochotona princeps	84.15	0.00e+00	899.00
IUUC-Ont-072580	Oreochromis niloticus	78.16	0.00e+00	1010.00
IUUC-Oan-073180	Ornithorhynchus anatinus	86.45	0.00e+00	1109.00
IUUC-Ocu-074026	Oryctolagus cuniculus	85.81	0.00e+00	1072.00
IUUC-Ola-086776	Oryzias latipes	76.79	0.00e+00	958.00
IUUC-Oga-088651	Otolemur garnettii	85.85	0.00e+00	1084.00
IUUC-Oar-089567	Ovis aries	85.44	0.00e+00	1072.00
IUUC-Ptr-091564	Pan troglodytes	85.35	0.00e+00	1117.00
IUUC-Pan-092578	Papio anubis	85.35	0.00e+00	1117.00
IUUC-Psi-093635	Pelodiscus sinensis	87.21	0.00e+00	1074.00
IUUC-Pma-094660	Petromyzon marinus	60.85	0.00e+00	731.00
IUUC-Pfo-097507	Poecilia formosa	77.68	0.00e+00	943.00
IUUC-Pab-098025	Pongo abelii	85.35	0.00e+00	1117.00
IUUC-Pca-101046	Procavia capensis	81.97	1.00e-172	599.00
IUUC-Ppe-101154	Prunus persica	34.48	6.00e-37	148.00
IUUC-Pva-102359	Pteropus vampyrus	88.41	0.00e+00	823.00
IUUC-Rno-105750	Rattus norvegicus	87.65	0.00e+00	1076.00
IUUC-Sha-107513	Sarcophilus harrisii	86.31	0.00e+00	1119.00
IUUC-Sar-113616	Sorex araneus	62.33	3.00e-101	362.00
IUUC-Ssc-116205	Sus scrofa	84.57	0.00e+00	906.00
IUUC-Tgu-117435	Taeniopygia guttata	87.38	0.00e+00	1126.00
IUUC-Tru-118709	Takifugu rubripes	76.58	0.00e+00	998.00
IUUC-Tsy-119466	Tarsius syrichta	89.44	0.00e+00	1008.00
IUUC-Tni-119988	Tetraodon nigroviridis	77.50	0.00e+00	996.00
IUUC-Tbe-127704	Tupaia belangeri	87.25	0.00e+00	962.00
IUUC-Ttr-128892	Tursiops truncatus	91.16	0.00e+00	871.00
IUUC-Vpa-130545	Vicugna pacos	84.74	0.00e+00	913.00
IUUC-Xtr-132289	Xenopus tropicalis	80.83	0.00e+00	986.00
IUUC-Xma-133419	Xiphophorus maculatus	83.30	0.00e+00	939.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence