iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-040512

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000108

Gene Name

OTUD7A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000003802.5	ENSGALT00000006032.5	ENSGALP00000006022.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	8.80e-41	139.9	199	369
UBD/ZnF/ZnF_A20	1.70e-14	53.8	847	879

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseylqkesdffsefieekedekefcqklvepe.....ak.g...... 77
           l+l+t+gDGnCLl+A+s +++g++d+d+ l++al++++r+ +++++ k+++++++++++ke+e++++ kl+++e     +k g      
   Q: 199  LPLATTGDGNCLLHAASLGMWGFHDRDLvLRKALYTMMRSGAEREALKRRWRWQQTQQNKEREWNELLKLASSEprthfSKnGgtgggv 287
           6899**********************************************************************88777444377899* PP
   S: 78   ...........eeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYdaLval 138
                      ee+h+f+La+iL+rpi+vv++++l++         ++ggi+lpl++ +++ +++p+vL+Y+++H++aLv++
   Q: 288  dnsedpvyeslEEFHVFVLAHILRRPIVVVADTMLRDsggeafapiPFGGIYLPLEVLPNRcHCSPLVLAYDQAHFSALVSM 369
           *********************************************************99999*****************986 PP

UBD/ZnF/ZnF_A20

   S: 3    skllCkk.gCgfYGnpetngyCSkCyreelrrr 34
           ++ +Ckk +C+fYG+pet++yCS+Cy+eel+rr
   Q: 847  TQNRCKKdNCSFYGRPETDNYCSYCYKEELKRR 879
           689*****************************9 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MPSSQSASPT AASCPAASLN DHMTLDMDAV LSDFVRSTGA EPGLARDLLE GKNWDLTAAL 60
SDYEQLRQVH TANLPQVFNE GKYCKQPEQP PQVTKAERPC LQRQDDIAQE KRLSRGISHA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTTCTA GCCAATCGGC GAGTCCTACT GCTGCCTCAT GTCCGGCAGC ATCTCTGAAT 60
GATCACATGA CTCTTGATAT GGATGCAGTC CTGTCAGACT TTGTTCGGTC CACGGGGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR002653--Znf_A20

PROSITE

PS50802--OTU
PS51036--ZF_A20

Pfam

PF02338--OTU
PF01754--zf-A20

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0070530--F:K63-linked polyubiquitin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0006955--P:immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0071947--P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0050727--P:regulation of inflammatory response
GO:0045088--P:regulation of innate immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001551	Ailuropoda melanoleuca	88.82	0.00e+00	946.00
IUUC-Apl-003825	Anas platyrhynchos	86.76	0.00e+00	1449.00
IUUC-Aca-004392	Anolis carolinensis	87.58	0.00e+00	1409.00
IUUC-Ame-011052	Astyanax mexicanus	75.65	0.00e+00	1215.00
IUUC-Bta-013296	Bos taurus	74.07	0.00e+00	1061.00
IUUC-Bol-015805	Brassica oleracea	32.89	1.30e+00	28.10
IUUC-Cja-019141	Callithrix jacchus	85.36	0.00e+00	983.00
IUUC-Cfa-020447	Canis familiaris	87.08	0.00e+00	1008.00
IUUC-Cpo-022059	Cavia porcellus	89.83	0.00e+00	888.00
IUUC-Csa-023263	Chlorocebus sabaeus	88.30	0.00e+00	1020.00
IUUC-Cho-024611	Choloepus hoffmanni	81.50	4.00e-158	551.00
IUUC-Dre-028617	Danio rerio	73.14	0.00e+00	1210.00
IUUC-Dno-029121	Dasypus novemcinctus	84.83	0.00e+00	1008.00
IUUC-Ete-033068	Echinops telfairi	66.55	0.00e+00	957.00
IUUC-Eca-034413	Equus caballus	87.86	0.00e+00	971.00
IUUC-Fca-036487	Felis catus	83.70	0.00e+00	911.00
IUUC-Fal-037145	Ficedula albicollis	90.03	0.00e+00	1436.00
IUUC-Fso-038203	Fusarium solani	26.23	7.40e-01	29.30
IUUC-Gmo-038786	Gadus morhua	64.59	0.00e+00	1073.00
IUUC-Gac-041599	Gasterosteus aculeatus	73.74	0.00e+00	1189.00
IUUC-Ggo-044819	Gorilla gorilla	75.31	0.00e+00	1082.00
IUUC-Hsa-046781	Homo sapiens	76.82	0.00e+00	1152.00
IUUC-Lch-050666	Latimeria chalumnae	83.28	0.00e+00	1359.00
IUUC-Loc-052841	Lepisosteus oculatus	89.45	0.00e+00	913.00
IUUC-Laf-053437	Loxodonta africana	84.09	0.00e+00	1019.00
IUUC-Mcc-055353	Macaca mulatta	76.31	0.00e+00	1145.00
IUUC-Mga-059741	Meleagris gallopavo	86.89	0.00e+00	1419.00
IUUC-Mmr-061437	Microcebus murinus	88.84	0.00e+00	1077.00
IUUC-Mdo-061907	Monodelphis domestica	89.40	0.00e+00	1446.00
IUUC-Mmu-064074	Mus musculus	75.68	0.00e+00	1130.00
IUUC-Mpu-066004	Mustela putorius furo	87.20	0.00e+00	945.00
IUUC-Nle-069182	Nomascus leucogenys	88.06	0.00e+00	1022.00
IUUC-Opr-070701	Ochotona princeps	80.69	0.00e+00	813.00
IUUC-Ont-072431	Oreochromis niloticus	86.47	0.00e+00	868.00
IUUC-Oan-073235	Ornithorhynchus anatinus	78.60	0.00e+00	1137.00
IUUC-Ocu-073935	Oryctolagus cuniculus	87.21	0.00e+00	951.00
IUUC-Ola-087026	Oryzias latipes	72.58	0.00e+00	1231.00
IUUC-Oga-088249	Otolemur garnettii	88.33	0.00e+00	1042.00
IUUC-Oar-089476	Ovis aries	74.38	0.00e+00	1139.00
IUUC-Ptr-090548	Pan troglodytes	87.54	0.00e+00	926.00
IUUC-Pan-092616	Papio anubis	78.88	0.00e+00	1132.00
IUUC-Psi-093126	Pelodiscus sinensis	89.29	0.00e+00	1422.00
IUUC-Pfo-096785	Poecilia formosa	85.88	0.00e+00	864.00
IUUC-Pab-098336	Pongo abelii	77.82	0.00e+00	1050.00
IUUC-Pca-100206	Procavia capensis	71.32	0.00e+00	694.00
IUUC-Rno-105483	Rattus norvegicus	72.97	0.00e+00	823.00
IUUC-Sha-106617	Sarcophilus harrisii	89.09	0.00e+00	924.00
IUUC-Ssc-115415	Sus scrofa	87.64	0.00e+00	926.00
IUUC-Tgu-117218	Taeniopygia guttata	89.92	0.00e+00	1113.00
IUUC-Tru-118720	Takifugu rubripes	86.53	0.00e+00	850.00
IUUC-Tni-120795	Tetraodon nigroviridis	85.88	0.00e+00	840.00
IUUC-Xtr-132158	Xenopus tropicalis	82.97	0.00e+00	1410.00
IUUC-Xma-133941	Xiphophorus maculatus	85.29	0.00e+00	845.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence