iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074671

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02007531

Gene Name

RNF149

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000013058.2	ENSOCUT00000013058.2	ENSOCUP00000011242.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.90e-06	28.3	154	195

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C e f  kd  ++lpC+H+fh+ C+  w         + +CP C+
   Q: 154  CAVCIENFkvKDIIRILPCKHIFHRICIDPW------LLDHRTCPMCK 195
           ********8866699****************......9999******6 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

GRAFKDKGLV TARRITSAVV GDNKELYGNL TAPMSHHLGT GNIVVIMISY PKGREILDLV 60
QKGIPVKMTI GIGTRHVQEF INGQSVVFVA IAFITMMIIS LAWLIFYYIQ RFLYTGSQFG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAGAGCCT TCAAAGACAA GGGATTGGTG ACGGCGCGGA GGATAACCTC GGCCGTGGTG 60
GGAGACAACA AGGAGCTCTA CGGGAACCTC ACGGCGCCCA TGTCCCACGC GGGTGAGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0035690--P:cellular response to drug
GO:0043409--P:negative regulation of MAPK cascade
GO:0031647--P:regulation of protein stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001968	Ailuropoda melanoleuca	80.07	8.00e-125	439.00
IUUC-Apl-004109	Anas platyrhynchos	67.92	1.00e-95	342.00
IUUC-Bta-012340	Bos taurus	76.14	6.00e-118	417.00
IUUC-Bol-016381	Brassica oleracea	35.94	6.00e-15	73.90
IUUC-Cja-019566	Callithrix jacchus	78.67	7.00e-118	417.00
IUUC-Cfa-020289	Canis familiaris	82.50	1.00e-108	385.00
IUUC-Cpo-021916	Cavia porcellus	74.85	7.00e-71	259.00
IUUC-Csa-024084	Chlorocebus sabaeus	80.07	2.00e-120	425.00
IUUC-Cho-024305	Choloepus hoffmanni	77.97	5.00e-117	413.00
IUUC-Cgl-026578	Colletotrichum gloeosporioides	48.08	2.00e-12	67.40
IUUC-Dno-030098	Dasypus novemcinctus	80.42	3.00e-128	451.00
IUUC-Dor-030620	Dipodomys ordii	75.21	3.00e-93	335.00
IUUC-Ete-032306	Echinops telfairi	79.04	3.00e-119	421.00
IUUC-Eca-033304	Equus caballus	79.63	2.00e-67	248.00
IUUC-Fca-035950	Felis catus	78.95	9.00e-113	399.00
IUUC-Fal-037429	Ficedula albicollis	68.44	8.00e-101	360.00
IUUC-Fso-038141	Fusarium solani	41.77	3.00e-16	79.70
IUUC-Ggr-040021	Gaeumannomyces graminis	40.51	2.00e-12	67.40
IUUC-Gga-041201	Gallus gallus	65.75	6.00e-99	353.00
IUUC-Ggo-045429	Gorilla gorilla	78.67	5.00e-121	427.00
IUUC-Hsa-046191	Homo sapiens	80.07	6.00e-120	423.00
IUUC-Itr-048018	Ictidomys tridecemlineatus	79.72	7.00e-114	403.00
IUUC-Lch-049498	Latimeria chalumnae	63.08	5.00e-97	347.00
IUUC-Lpe-050695	Leersia perrieri	32.33	1.00e-14	73.60
IUUC-Laf-054239	Loxodonta africana	73.61	2.00e-104	372.00
IUUC-Meu-056382	Macropus eugenii	71.48	2.00e-102	365.00
IUUC-Mla-058935	Melampsora laricipopulina	37.80	3.00e-09	57.00
IUUC-Mga-059435	Meleagris gallopavo	66.13	6.00e-65	239.00
IUUC-Mmr-061513	Microcebus murinus	78.45	1.00e-120	426.00
IUUC-Mdo-063028	Monodelphis domestica	71.43	7.00e-108	384.00
IUUC-Mmu-063545	Mus musculus	78.45	1.00e-114	406.00
IUUC-Mpu-066370	Mustela putorius furo	78.67	5.00e-121	427.00
IUUC-Mlu-067271	Myotis lucifugus	73.26	1.00e-107	382.00
IUUC-Nle-069207	Nomascus leucogenys	78.67	1.00e-120	426.00
IUUC-Opr-070704	Ochotona princeps	82.19	1.00e-108	385.00
IUUC-Oan-072837	Ornithorhynchus anatinus	69.58	2.00e-105	375.00
IUUC-Oba-075253	Oryza barthii	41.18	1.00e-14	73.20
IUUC-Ogl-077917	Oryza glaberrima	36.99	1.00e-12	67.40
IUUC-Ogu-078288	Oryza glumaepatula	36.99	2.00e-12	67.00
IUUC-Ome-081134	Oryza meridionalis	36.99	1.00e-12	67.00
IUUC-Oni-082980	Oryza nivara	36.99	1.00e-12	67.00
IUUC-Opu-084047	Oryza punctata	37.21	2.00e-13	69.70
IUUC-Oru-084483	Oryza rufipogon	36.99	1.00e-12	67.40
IUUC-Osa-085825	Oryza sativa	40.00	3.00e-15	74.70
IUUC-Oga-089083	Otolemur garnettii	77.27	9.00e-121	426.00
IUUC-Oar-089254	Ovis aries	76.92	3.00e-106	377.00
IUUC-Ptr-090940	Pan troglodytes	78.32	1.00e-120	426.00
IUUC-Pan-092636	Papio anubis	78.40	2.00e-120	425.00
IUUC-Psi-093435	Pelodiscus sinensis	73.31	4.00e-92	330.00
IUUC-Pab-098525	Pongo abelii	79.49	1.00e-115	409.00
IUUC-Pva-102395	Pteropus vampyrus	76.57	9.00e-120	423.00
IUUC-Pgr-103263	Puccinia graminis	39.24	5.00e-11	63.20
IUUC-Rno-105789	Rattus norvegicus	78.09	4.00e-115	407.00
IUUC-Sha-107305	Sarcophilus harrisii	69.33	2.00e-91	328.00
IUUC-Ssc-115598	Sus scrofa	76.92	1.00e-116	412.00
IUUC-Tgu-116463	Taeniopygia guttata	68.44	1.00e-100	359.00
IUUC-Tsy-118915	Tarsius syrichta	80.16	1.00e-108	385.00
IUUC-Tre-121978	Trichoderma reesei	48.98	1.00e-12	67.80
IUUC-Tme-126970	Tuber melanosporum	49.06	7.00e-13	68.60
IUUC-Tbe-127906	Tupaia belangeri	65.45	2.00e-81	294.00
IUUC-Xtr-131821	Xenopus tropicalis	63.25	1.00e-93	336.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence