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Tag Content
UUCD2 ID IUUC-Ola-087031
UUCD1 version UUC-OrL-00857
Ensembl Protein ID ENSORLP00000022663.1
UniProt Accession H2MV37; H2MV37_ORYLA
Genbank Protein ID ENSORLP00000022663
Protein Name Histone deacetylase
Genbank Nucleotide ID BAAF04023972
Gene Name hdac4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSORLG00000018092.1 ENSORLT00000022664.1 ENSORLP00000022663.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/Other 66.67 0.00e+00 1192.00 IUUC-Hsa-046925
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Oryzias latipes
Functional Description
(View)

Functional Description


     Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
 Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Protein Sequence
(Fasta)
LKAKRLYRLS CLVDVSPAAL PSQVPPTSTA ILPMDLRVVD HHHKKKQTPP GHQEHQLQHE 60
LVALKHKQQL QRQLLIAEFQ RQHEQLSRQH EAQLQEHIKH QQDLLALKHQ QELLEHHRKM 120
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Protein Fasta Sequence


>IUUC-Ola-087031|E3,E3 activity/Other|Oryzias latipes
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTAAAGGCTA AACGACTTTA TCGCTTGTCT TGTTTAGTGG ATGTGAGCCC GGCAGCGCTG 60
CCCTCGCAGG TGCCCCCCAC TTCAACCGCC ATCCTTCCCA TGGACCTGCG CGTAGTGGAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ola-087031|E3,E3 activity/Other|Oryzias latipes
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR033660--HDAC4
IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR024643--Hist_deacetylase_Gln_rich_N
IPR017320--Histone_deAcase_II_euk
IPR015943--WD40/YVTN_repeat-like_dom
Pfam

PF12203--HDAC4_Gln
PF00850--Hist_deacetyl
PRINTS

PR01270--HDASUPER
Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0032041--F:NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0048701--P:embryonic cranial skeleton morphogenesis
GO:0001755--P:neural crest cell migration
GO:0090299--P:regulation of neural crest formation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000749 Aegilops tauschii 44.13 2.00e-60 226.00
IUUC-Aml-002279 Ailuropoda melanoleuca 79.87 0.00e+00 788.00
IUUC-Atr-002745 Amborella trichopoda 37.35 9.00e-75 274.00
IUUC-Apl-003250 Anas platyrhynchos 79.66 0.00e+00 798.00
IUUC-Aca-004668 Anolis carolinensis 79.14 0.00e+00 789.00
IUUC-Aly-006432 Arabidopsis lyrata 44.19 1.00e-70 261.00
IUUC-Ath-007355 Arabidopsis thaliana 43.41 1.00e-77 283.00
IUUC-Ago-007972 Ashbya gossypii 36.68 4.00e-68 252.00
IUUC-Acl-008187 Aspergillus clavatus 38.78 3.00e-72 266.00
IUUC-Afl-008399 Aspergillus flavus 42.29 3.00e-40 159.00
IUUC-Afu-008954 Aspergillus fumigatus 36.29 2.00e-60 226.00
IUUC-Ani-009142 Aspergillus nidulans 38.40 2.00e-67 250.00
IUUC-Ang-009522 Aspergillus niger 29.60 5.00e-22 99.40
IUUC-Aor-010069 Aspergillus oryzae 35.95 1.00e-64 240.00
IUUC-Ate-010291 Aspergillus terreus 39.19 3.00e-73 269.00
IUUC-Ame-010780 Astyanax mexicanus 39.81 3.00e-74 273.00
IUUC-Bta-013215 Bos taurus 70.04 0.00e+00 1159.00
IUUC-Bci-013789 Botrytis cinerea 36.02 1.00e-66 248.00
IUUC-Bdi-014007 Brachypodium distachyon 42.05 2.00e-72 267.00
IUUC-Bol-015468 Brassica oleracea 41.00 3.00e-78 286.00
IUUC-Bra-016680 Brassica rapa 41.46 9.00e-79 287.00
IUUC-Cel-018220 Caenorhabditis elegans 40.32 4.00e-67 249.00
IUUC-Cja-019816 Callithrix jacchus 78.35 0.00e+00 786.00
IUUC-Cfa-020861 Canis familiaris 69.80 0.00e+00 1148.00
IUUC-Cpo-021562 Cavia porcellus 79.66 0.00e+00 791.00
IUUC-Cre-022561 Chlamydomonas reinhardtii 51.80 6.00e-54 203.00
IUUC-Csa-023612 Chlorocebus sabaeus 78.56 0.00e+00 789.00
IUUC-Csv-026359 Ciona savignyi 52.36 8.00e-89 319.00
IUUC-Cgl-026709 Colletotrichum gloeosporioides 36.21 6.00e-66 244.00
IUUC-Cne-026978 Cryptococcus neoformans 39.39 5.00e-73 268.00
IUUC-Dre-028284 Danio rerio 83.40 0.00e+00 827.00
IUUC-Dno-029951 Dasypus novemcinctus 74.73 0.00e+00 728.00
IUUC-Dor-030362 Dipodomys ordii 58.46 0.00e+00 934.00
IUUC-Dse-031186 Dothistroma septosporum 34.50 1.00e-61 231.00
IUUC-Dme-031766 Drosophila melanogaster 57.52 6.00e-153 535.00
IUUC-Ete-032279 Echinops telfairi 35.34 1.00e-53 204.00
IUUC-Eca-033842 Equus caballus 43.98 1.00e-75 278.00
IUUC-Eeu-034487 Erinaceus europaeus 50.00 2.00e-59 224.00
IUUC-Fca-036187 Felis catus 70.52 0.00e+00 1196.00
IUUC-Fox-038067 Fusarium oxysporum 35.24 3.00e-66 246.00
IUUC-Fso-038263 Fusarium solani 37.68 2.00e-68 253.00
IUUC-Gmo-038473 Gadus morhua 78.13 0.00e+00 744.00
IUUC-Ggr-040062 Gaeumannomyces graminis 40.22 7.00e-66 245.00
IUUC-Gga-040501 Gallus gallus 79.87 0.00e+00 798.00
IUUC-Gac-042335 Gasterosteus aculeatus 80.02 0.00e+00 1456.00
IUUC-Gma-043738 Glycine max 40.64 4.00e-69 255.00
IUUC-Ggo-045380 Gorilla gorilla 77.94 0.00e+00 756.00
IUUC-Hsa-046925 Homo sapiens 78.76 0.00e+00 793.00
IUUC-Hvu-047285 Hordeum vulgare 42.65 4.00e-71 261.00
IUUC-Itr-048036 Ictidomys tridecemlineatus 67.88 0.00e+00 1159.00
IUUC-Kpa-049281 Komagataella pastoris 37.56 8.00e-71 261.00
IUUC-Lch-050325 Latimeria chalumnae 77.32 0.00e+00 766.00
IUUC-Lpe-051214 Leersia perrieri 38.44 3.00e-75 276.00
IUUC-Loc-052231 Lepisosteus oculatus 82.05 0.00e+00 786.00
IUUC-Lma-053263 Leptosphaeria maculans 39.22 4.00e-74 273.00
IUUC-Laf-054490 Loxodonta africana 79.23 0.00e+00 785.00
IUUC-Mcc-055265 Macaca mulatta 78.16 0.00e+00 792.00
IUUC-Meu-056676 Macropus eugenii 75.21 1.00e-162 566.00
IUUC-Mor-057095 Magnaporthe oryzae 37.47 1.00e-67 251.00
IUUC-Mpo-057389 Magnaporthe poae 39.39 1.00e-64 241.00
IUUC-Mtr-058463 Medicago truncatula 38.74 1.00e-70 260.00
IUUC-Mla-059143 Melampsora laricipopulina 39.25 6.00e-68 251.00
IUUC-Mmr-061633 Microcebus murinus 62.35 0.00e+00 1040.00
IUUC-Mdo-062198 Monodelphis domestica 43.12 2.00e-75 277.00
IUUC-Mmu-063089 Mus musculus 80.51 0.00e+00 795.00
IUUC-Mac-064630 Musa acuminata 43.10 3.00e-74 272.00
IUUC-Mpu-065887 Mustela putorius furo 79.87 0.00e+00 791.00
IUUC-Mlu-067470 Myotis lucifugus 68.29 0.00e+00 1198.00
IUUC-Nfi-068404 Neosartorya fischeri 39.48 1.00e-71 264.00
IUUC-Ncr-068672 Neurospora crassa 35.42 4.00e-67 249.00
IUUC-Nle-069099 Nomascus leucogenys 65.88 6.00e-121 428.00
IUUC-Opr-071074 Ochotona princeps 44.09 2.00e-84 307.00
IUUC-Ont-071613 Oreochromis niloticus 83.55 0.00e+00 1471.00
IUUC-Oan-073275 Ornithorhynchus anatinus 79.87 0.00e+00 788.00
IUUC-Ocu-074627 Oryctolagus cuniculus 44.09 3.00e-81 297.00
IUUC-Oba-075489 Oryza barthii 42.53 2.00e-74 273.00
IUUC-Obr-076150 Oryza brachyantha 42.53 3.00e-75 276.00
IUUC-Ogl-077437 Oryza glaberrima 42.53 8.00e-75 275.00
IUUC-Ogu-078370 Oryza glumaepatula 42.24 2.00e-74 273.00
IUUC-Oin-079210 Oryza indica 42.24 2.00e-74 273.00
IUUC-Olo-080971 Oryza longistaminata 43.52 2.00e-65 243.00
IUUC-Oni-082031 Oryza nivara 42.24 3.00e-74 273.00
IUUC-Opu-083471 Oryza punctata 41.95 2.00e-75 276.00
IUUC-Oru-084755 Oryza rufipogon 42.24 2.00e-74 273.00
IUUC-Osa-085447 Oryza sativa 42.24 2.00e-74 273.00
IUUC-Oga-088201 Otolemur garnettii 78.54 0.00e+00 775.00
IUUC-Oar-089997 Ovis aries 77.54 0.00e+00 765.00
IUUC-Ptr-091116 Pan troglodytes 78.76 0.00e+00 792.00
IUUC-Pan-092132 Papio anubis 78.56 0.00e+00 786.00
IUUC-Psi-093734 Pelodiscus sinensis 78.81 0.00e+00 765.00
IUUC-Pma-094347 Petromyzon marinus 68.10 0.00e+00 664.00
IUUC-Pno-095131 Phaeosphaeria nodorum 45.52 3.00e-65 242.00
IUUC-Ppa-095550 Physcomitrella patens 44.51 9.00e-74 271.00
IUUC-Pfo-096293 Poecilia formosa 80.35 0.00e+00 1469.00
IUUC-Pab-098491 Pongo abelii 71.96 0.00e+00 690.00
IUUC-Pop-099174 Populus trichocarpa 41.36 2.00e-75 276.00
IUUC-Pca-101004 Procavia capensis 67.30 6.00e-92 332.00
IUUC-Ppe-101644 Prunus persica 39.79 4.00e-76 278.00
IUUC-Pva-102961 Pteropus vampyrus 52.42 4.00e-110 392.00
IUUC-Ptt-103841 Puccinia triticina 39.12 1.00e-66 247.00
IUUC-Pte-104383 Pyrenophora teres 39.29 9.00e-76 278.00
IUUC-Pyt-104427 Pyrenophora triticirepentis 38.62 4.00e-74 272.00
IUUC-Rno-105005 Rattus norvegicus 79.87 0.00e+00 787.00
IUUC-Sce-106274 Saccharomyces cerevisiae 35.28 2.00e-66 247.00
IUUC-Sha-107646 Sarcophilus harrisii 82.76 4.00e-162 565.00
IUUC-Sja-107915 Schizosaccharomyces japonicus 37.00 1.00e-67 251.00
IUUC-Spo-108300 Schizosaccharomyces pombe 37.18 1.00e-68 253.00
IUUC-Smo-109615 Selaginella moellendorffii 43.38 8.00e-79 288.00
IUUC-Sit-110160 Setaria italica 42.07 6.00e-70 258.00
IUUC-Sly-111164 Solanum lycopersicum 40.05 3.00e-80 292.00
IUUC-Stu-112685 Solanum tuberosum 38.60 4.00e-58 219.00
IUUC-Sar-113692 Sorex araneus 36.45 5.00e-50 193.00
IUUC-Sbi-114301 Sorghum bicolor 41.09 1.00e-68 254.00
IUUC-Sre-115013 Sporisorium reilianum 40.83 1.00e-68 254.00
IUUC-Ssc-115428 Sus scrofa 79.01 0.00e+00 783.00
IUUC-Tgu-116776 Taeniopygia guttata 80.09 0.00e+00 795.00
IUUC-Tru-118180 Takifugu rubripes 82.04 0.00e+00 1474.00
IUUC-Tsy-119468 Tarsius syrichta 56.20 6.00e-130 458.00
IUUC-Tni-120196 Tetraodon nigroviridis 83.30 0.00e+00 848.00
IUUC-Tca-121312 Theobroma cacao 41.37 2.00e-79 289.00
IUUC-Tre-121930 Trichoderma reesei 37.24 3.00e-71 262.00
IUUC-Tvi-122373 Trichoderma virens 38.42 1.00e-69 257.00
IUUC-Tae-123064 Triticum aestivum 38.26 3.00e-65 242.00
IUUC-Tme-127027 Tuber melanosporum 37.31 1.00e-60 227.00
IUUC-Tbe-127675 Tupaia belangeri 39.41 3.00e-19 91.30
IUUC-Ttr-128360 Tursiops truncatus 82.04 0.00e+00 719.00
IUUC-Uma-129408 Ustilago maydis 40.46 5.00e-68 252.00
IUUC-Vda-129994 Verticillium dahliae 43.12 2.00e-63 236.00
IUUC-Vpa-130525 Vicugna pacos 57.89 3.00e-16 80.50
IUUC-Vvi-131038 Vitis vinifera 38.93 8.00e-77 281.00
IUUC-Xtr-132956 Xenopus tropicalis 77.39 0.00e+00 774.00
IUUC-Xma-134265 Xiphophorus maculatus 79.01 0.00e+00 1471.00
IUUC-Yli-134680 Yarrowia lipolytica 40.10 4.00e-70 259.00
IUUC-Zma-135110 Zea mays 41.38 1.00e-69 256.00
Created Date 25-Jun-2017

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