iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088519

Ensembl Protein ID

ENSOGAP00000003606.2

UniProt Accession

H0WP17; H0WP17_OTOGA

Genbank Protein ID

ENSOGAP00000003606

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03038663

Gene Name

RC3H1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000004044.2	ENSOGAT00000004048.2	ENSOGAP00000003606.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	90.22	0.00e+00	1758.00	IUUC-Hsa-046163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MPVQAPQWTD FLSCPICTQT FDETIRKPIS LGCGHTVCKM CLNKLHRKAC PFDQTTINTD 60
IELLPVNSAL LQLVGAQVPE QQPITLCSGV EDTKHYEEAK KCVEELALYL KPLSSARGVG 120

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Nucleotide Sequence
(Fasta)

ATGCCTGTAC AAGCTCCACA ATGGACGGAT TTCCTCTCCT GCCCAATTTG CACTCAGACT 60
TTCGACGAAA CGATTCGAAA GCCCATCAGT TTGGGCTGTG GCCATACTGT CTGCAAGATG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR032671--RC3H1
IPR027370--Znf-RING_LisH
IPR000571--Znf_CCCH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50103--ZF_C3H1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00642--zf-CCCH
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00356--ZnF_C3H1

Gene Ontology

GO:0010494--C:cytoplasmic stress granule
GO:0000932--C:P-body
GO:0003730--F:mRNA 3'-UTR binding
GO:0035613--F:RNA stem-loop binding
GO:0008270--F:zinc ion binding
GO:0061158--P:3'-UTR-mediated mRNA destabilization
GO:0001782--P:B cell homeostasis
GO:0071347--P:cellular response to interleukin-1
GO:0033962--P:cytoplasmic mRNA processing body assembly
GO:0048535--P:lymph node development
GO:0046007--P:negative regulation of activated T cell proliferation
GO:0030889--P:negative regulation of B cell proliferation
GO:0002635--P:negative regulation of germinal center formation
GO:0045623--P:negative regulation of T-helper cell differentiation
GO:0000288--P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0061014--P:positive regulation of mRNA catabolic process
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0050856--P:regulation of T cell receptor signaling pathway
GO:0048536--P:spleen development
GO:0043029--P:T cell homeostasis
GO:0042098--P:T cell proliferation
GO:0061470--P:T follicular helper cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001700	Ailuropoda melanoleuca	89.42	0.00e+00	1775.00
IUUC-Apl-003290	Anas platyrhynchos	80.03	0.00e+00	1665.00
IUUC-Aca-004905	Anolis carolinensis	77.47	0.00e+00	1541.00
IUUC-Cja-019907	Callithrix jacchus	89.70	0.00e+00	1815.00
IUUC-Cfa-020679	Canis familiaris	89.68	0.00e+00	1762.00
IUUC-Cpo-022110	Cavia porcellus	85.31	0.00e+00	1774.00
IUUC-Csa-024166	Chlorocebus sabaeus	90.07	0.00e+00	1747.00
IUUC-Dno-029870	Dasypus novemcinctus	90.71	0.00e+00	906.00
IUUC-Dor-030934	Dipodomys ordii	87.59	0.00e+00	818.00
IUUC-Ete-032652	Echinops telfairi	86.50	0.00e+00	1207.00
IUUC-Eca-033236	Equus caballus	89.24	0.00e+00	1747.00
IUUC-Eeu-035091	Erinaceus europaeus	78.34	2.00e-180	626.00
IUUC-Fca-035773	Felis catus	89.79	0.00e+00	1764.00
IUUC-Fal-036972	Ficedula albicollis	79.39	0.00e+00	1648.00
IUUC-Ggo-044691	Gorilla gorilla	83.79	0.00e+00	1647.00
IUUC-Hsa-046163	Homo sapiens	90.22	0.00e+00	1821.00
IUUC-Itr-048266	Ictidomys tridecemlineatus	93.68	0.00e+00	1054.00
IUUC-Lch-050667	Latimeria chalumnae	68.09	0.00e+00	1358.00
IUUC-Loc-052404	Lepisosteus oculatus	62.36	0.00e+00	1150.00
IUUC-Laf-053618	Loxodonta africana	90.17	0.00e+00	1726.00
IUUC-Mcc-054692	Macaca mulatta	90.22	0.00e+00	1827.00
IUUC-Meu-056025	Macropus eugenii	86.65	0.00e+00	941.00
IUUC-Mmr-061188	Microcebus murinus	91.36	0.00e+00	1801.00
IUUC-Mdo-063035	Monodelphis domestica	85.39	0.00e+00	1716.00
IUUC-Mmu-064146	Mus musculus	85.54	0.00e+00	1724.00
IUUC-Mpu-066217	Mustela putorius furo	89.07	0.00e+00	1747.00
IUUC-Mlu-068023	Myotis lucifugus	88.54	0.00e+00	1770.00
IUUC-Nle-069506	Nomascus leucogenys	90.13	0.00e+00	1824.00
IUUC-Opr-070587	Ochotona princeps	75.44	0.00e+00	1400.00
IUUC-Oan-073500	Ornithorhynchus anatinus	84.05	0.00e+00	1747.00
IUUC-Ocu-074299	Oryctolagus cuniculus	88.91	0.00e+00	1660.00
IUUC-Oar-089246	Ovis aries	89.40	0.00e+00	1647.00
IUUC-Ptr-091102	Pan troglodytes	90.31	0.00e+00	1825.00
IUUC-Pan-091952	Papio anubis	90.15	0.00e+00	1823.00
IUUC-Pfo-097227	Poecilia formosa	55.44	0.00e+00	989.00
IUUC-Pab-097975	Pongo abelii	86.96	0.00e+00	1731.00
IUUC-Pca-101127	Procavia capensis	82.42	0.00e+00	1132.00
IUUC-Pva-102431	Pteropus vampyrus	85.45	0.00e+00	1668.00
IUUC-Sha-106690	Sarcophilus harrisii	84.34	0.00e+00	1708.00
IUUC-Ssc-116189	Sus scrofa	89.96	0.00e+00	1709.00
IUUC-Tgu-116527	Taeniopygia guttata	79.75	0.00e+00	1657.00
IUUC-Tru-118389	Takifugu rubripes	55.80	0.00e+00	1036.00
IUUC-Tsy-119193	Tarsius syrichta	86.60	0.00e+00	1701.00
IUUC-Tni-119790	Tetraodon nigroviridis	56.67	0.00e+00	937.00
IUUC-Tbe-127445	Tupaia belangeri	81.75	0.00e+00	1342.00
IUUC-Ttr-128877	Tursiops truncatus	89.27	0.00e+00	1702.00
IUUC-Vpa-130054	Vicugna pacos	94.42	0.00e+00	886.00
IUUC-Xtr-132274	Xenopus tropicalis	71.85	0.00e+00	1413.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence