iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004256

Ensembl Protein ID

ENSACAP00000003114.3

UniProt Accession

G1KBN3; G1KBN3_ANOCA

Protein Name

Uncharacterized protein

Gene Name

PACSIN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000003162.3	ENSACAT00000003193.3	ENSACAP00000003114.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.70e-16	58.4	400	455

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +v++lydy++q+ deL++k+G+ +  i  ee ++gW+kg + l+g+ Gl P+n+vek+
   Q: 400  RVRALYDYTGQEADELSFKAGEELMKI-SEEDEQGWCKG-RLLTGQVGLYPANYVEKV 455
           589*********************999.999********.5***************98 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSAEEDAGGE VPSGSFWEPG NYKKTVKRVD DGNRLCNDLV SCFQERAKIE KNYAQQLTDW 60
SRKWRSAVEK GPQYGTLEKA WHAFLTAADK LSEIHLEVRN HLAGVDSDKV KAWQKEAFHK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTCTTCCT TTCTGTTGAA ATTGTCCACA TGCTTGTGGA TTTCAGTGGC TTCTCTGTGT 60
AGTCTGACAT AAGGGTTGTT GTTACGAGTG TTAGGAAGAA CTTTCTGAGC TGCCTCAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR031160--F_BAR
IPR001060--FCH_dom
IPR028523--PACSIN3
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0019855--F:calcium channel inhibitor activity
GO:0008289--F:lipid binding
GO:0051926--P:negative regulation of calcium ion transport
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0051044--P:positive regulation of membrane protein ectodomain proteolysis
GO:0030100--P:regulation of endocytosis

KEGG

acs:100567497

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001906	Ailuropoda melanoleuca	61.71	1.00e-170	592.00
IUUC-Apl-003211	Anas platyrhynchos	84.31	0.00e+00	787.00
IUUC-Ame-011049	Astyanax mexicanus	64.29	4.00e-159	553.00
IUUC-Bta-013322	Bos taurus	65.53	1.00e-166	578.00
IUUC-Cja-018907	Callithrix jacchus	63.74	2.00e-169	588.00
IUUC-Cfa-021126	Canis familiaris	65.05	7.00e-172	596.00
IUUC-Cpo-021491	Cavia porcellus	65.05	4.00e-171	593.00
IUUC-Csa-023107	Chlorocebus sabaeus	64.62	2.00e-171	594.00
IUUC-Cne-026895	Cryptococcus neoformans	39.34	7.00e-09	53.90
IUUC-Dre-027933	Danio rerio	65.77	3.00e-157	548.00
IUUC-Dno-029002	Dasypus novemcinctus	64.84	2.00e-168	585.00
IUUC-Eca-033824	Equus caballus	64.84	2.00e-170	592.00
IUUC-Eeu-035122	Erinaceus europaeus	67.18	2.00e-103	368.00
IUUC-Fca-036420	Felis catus	65.05	1.00e-173	602.00
IUUC-Fal-037277	Ficedula albicollis	85.37	0.00e+00	796.00
IUUC-Gga-040941	Gallus gallus	84.68	0.00e+00	783.00
IUUC-Gac-041374	Gasterosteus aculeatus	62.20	1.00e-139	489.00
IUUC-Ggo-045211	Gorilla gorilla	64.40	7.00e-171	593.00
IUUC-Hsa-046053	Homo sapiens	64.62	2.00e-171	594.00
IUUC-Itr-047939	Ictidomys tridecemlineatus	65.49	2.00e-171	594.00
IUUC-Loc-052808	Lepisosteus oculatus	68.78	0.00e+00	626.00
IUUC-Laf-054211	Loxodonta africana	64.40	1.00e-161	562.00
IUUC-Mcc-055044	Macaca mulatta	64.62	2.00e-171	594.00
IUUC-Mga-059216	Meleagris gallopavo	84.31	0.00e+00	786.00
IUUC-Mmr-061172	Microcebus murinus	64.40	3.00e-171	593.00
IUUC-Mdo-062600	Monodelphis domestica	64.18	7.00e-173	599.00
IUUC-Mmu-063218	Mus musculus	65.05	3.00e-171	594.00
IUUC-Mpu-066819	Mustela putorius furo	59.76	5.00e-169	587.00
IUUC-Mlu-067597	Myotis lucifugus	64.40	5.00e-170	590.00
IUUC-Nle-069195	Nomascus leucogenys	63.96	1.00e-169	588.00
IUUC-Opr-071050	Ochotona princeps	66.15	2.00e-174	605.00
IUUC-Ont-071612	Oreochromis niloticus	62.18	1.00e-151	529.00
IUUC-Oan-073256	Ornithorhynchus anatinus	64.33	7.00e-169	586.00
IUUC-Ocu-074653	Oryctolagus cuniculus	65.71	5.00e-173	600.00
IUUC-Oga-089040	Otolemur garnettii	63.52	9.00e-169	585.00
IUUC-Oar-089918	Ovis aries	65.08	4.00e-167	580.00
IUUC-Ptr-091307	Pan troglodytes	64.62	2.00e-171	594.00
IUUC-Pan-092512	Papio anubis	64.62	2.00e-171	594.00
IUUC-Pfo-096881	Poecilia formosa	62.18	5.00e-153	533.00
IUUC-Pab-098620	Pongo abelii	64.62	2.00e-171	594.00
IUUC-Pva-102464	Pteropus vampyrus	62.42	4.00e-162	563.00
IUUC-Rno-106091	Rattus norvegicus	64.84	1.00e-170	592.00
IUUC-Sha-107474	Sarcophilus harrisii	64.40	2.00e-174	604.00
IUUC-Ssc-116128	Sus scrofa	65.71	3.00e-174	604.00
IUUC-Tgu-117511	Taeniopygia guttata	79.75	0.00e+00	753.00
IUUC-Tru-118005	Takifugu rubripes	63.74	6.00e-147	513.00
IUUC-Tni-119851	Tetraodon nigroviridis	64.63	1.00e-143	502.00
IUUC-Ttr-129313	Tursiops truncatus	65.05	2.00e-172	598.00
IUUC-Vpa-130760	Vicugna pacos	73.77	4.00e-82	298.00
IUUC-Xtr-132697	Xenopus tropicalis	62.91	1.00e-151	529.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence