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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Sce-106445
Ensembl Protein ID YER051W
UniProt Accession P40034; D3DLV3; JHD1_YEAST
Genbank Protein ID AAB64586.1; DAA07707.1
Protein Name JmjC domain-containing histone demethylation protein 1; Jumonji/ARID domain-containing protein 1; ScJHDM1; [Histone-H3]-lysine-36 demethylase 1
Genbank Nucleotide ID U18796; BK006939
Gene Name JHD1; YER051W
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YER051W YER051W YER051W
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
IIDiRefIndexHINTMentha
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/SCF/F-box 40.00 3.00e-50 196.00 IUUC-Dme-032039
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description


     Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Does not demethylate H3 'Lys-4' nor 'Lys-79'.
 Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Does not demethylate H3 'Lys-4' nor 'Lys-79'.
Protein Sequence
(Fasta)
MQDPNICQHC QLKDNPGALI WVKCDSCPQW VHVKCVPLKR IHYSNLTSSE VLSYPNSAKQ 60
IKSYRCPNHK EGEYLTAYAL ITQKGKRQRN KENPEDSHIN KRYNFRKKKL LDYIALNEGE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sce-106445|E3,F-box|Saccharomyces cerevisiae
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Nucleotide Sequence
(Fasta)
ATGCAAGATC CCAATATTTG CCAGCATTGC CAGTTGAAGG ATAATCCAGG CGCATTAATT 60
TGGGTGAAGT GTGATAGTTG CCCGCAGTGG GTCCACGTGA AATGCGTGCC TTTGAAACGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sce-106445|E3,F-box|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0223--Dioxygenase
KW-0408--Iron
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0560--Oxidoreductase
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR003347--JmjC_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51184--JMJC
SMART

SM00558--JmjC
SM00249--PHD
Gene Ontology

GO:0005634--C:nucleus
GO:0051864--F:histone demethylase activity (H3-K36 specific)
GO:0035064--F:methylated histone binding
GO:0008270--F:zinc ion binding
GO:0016577--P:histone demethylation
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated
KEGG sce:YER051W
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001165 Aegilops tauschii 32.65 4.00e-04 36.20
IUUC-Aml-002052 Ailuropoda melanoleuca 43.46 2.00e-46 179.00
IUUC-Atr-002475 Amborella trichopoda 30.16 1.00e-04 38.10
IUUC-Apl-003192 Anas platyrhynchos 39.92 9.00e-50 190.00
IUUC-Aca-004247 Anolis carolinensis 42.80 6.00e-49 187.00
IUUC-Aly-005868 Arabidopsis lyrata 32.81 8.00e-05 38.50
IUUC-Ath-007447 Arabidopsis thaliana 32.81 9.00e-05 38.50
IUUC-Ago-007912 Ashbya gossypii 42.37 2.00e-108 384.00
IUUC-Acl-008303 Aspergillus clavatus 29.61 8.00e-55 207.00
IUUC-Afl-008579 Aspergillus flavus 41.54 2.00e-18 85.90
IUUC-Afu-008903 Aspergillus fumigatus 30.29 8.00e-55 207.00
IUUC-Ani-009279 Aspergillus nidulans 30.65 2.00e-51 196.00
IUUC-Ang-009645 Aspergillus niger 44.49 3.00e-54 205.00
IUUC-Aor-010233 Aspergillus oryzae 43.62 1.00e-52 199.00
IUUC-Ate-010345 Aspergillus terreus 44.03 2.00e-53 203.00
IUUC-Ame-011753 Astyanax mexicanus 38.20 2.00e-52 199.00
IUUC-Bta-013531 Bos taurus 44.07 5.00e-49 187.00
IUUC-Bdi-014599 Brachypodium distachyon 32.81 9.00e-05 38.50
IUUC-Bol-015692 Brassica oleracea 30.16 1.00e-05 40.80
IUUC-Bra-017743 Brassica rapa 30.16 1.00e-05 41.20
IUUC-Cel-018303 Caenorhabditis elegans 37.12 3.00e-40 158.00
IUUC-Cja-019030 Callithrix jacchus 43.46 2.00e-46 179.00
IUUC-Cfa-020644 Canis familiaris 43.46 2.00e-46 179.00
IUUC-Cpo-022055 Cavia porcellus 43.46 2.00e-46 179.00
IUUC-Cre-022852 Chlamydomonas reinhardtii 60.00 6.30e-01 28.10
IUUC-Csa-023379 Chlorocebus sabaeus 43.46 2.00e-46 179.00
IUUC-Cho-024541 Choloepus hoffmanni 37.78 2.00e-29 122.00
IUUC-Cin-025140 Ciona intestinalis 39.92 4.00e-50 191.00
IUUC-Csv-025861 Ciona savignyi 40.50 1.00e-53 202.00
IUUC-Cne-026797 Cryptococcus neoformans 36.17 5.00e-48 184.00
IUUC-Cme-027118 Cyanidioschyzon merolae 32.00 3.00e-38 151.00
IUUC-Dre-028182 Danio rerio 43.51 1.00e-50 193.00
IUUC-Dno-029268 Dasypus novemcinctus 43.46 2.00e-46 179.00
IUUC-Dor-030736 Dipodomys ordii 38.71 4.00e-46 178.00
IUUC-Dse-031402 Dothistroma septosporum 31.98 7.00e-53 201.00
IUUC-Dme-032039 Drosophila melanogaster 40.00 2.00e-51 196.00
IUUC-Ete-032467 Echinops telfairi 43.51 1.00e-50 192.00
IUUC-Eca-033526 Equus caballus 43.46 2.00e-46 179.00
IUUC-Eeu-035273 Erinaceus europaeus 47.20 5.00e-39 154.00
IUUC-Fca-035532 Felis catus 43.46 2.00e-46 179.00
IUUC-Fal-037140 Ficedula albicollis 40.30 5.00e-50 191.00
IUUC-Gmo-039539 Gadus morhua 43.46 1.00e-50 192.00
IUUC-Gga-040418 Gallus gallus 39.92 6.00e-50 190.00
IUUC-Gac-041914 Gasterosteus aculeatus 42.19 1.00e-50 193.00
IUUC-Gma-043376 Glycine max 32.65 3.00e-04 36.60
IUUC-Ggo-044712 Gorilla gorilla 30.43 2.00e-46 179.00
IUUC-Hsa-046180 Homo sapiens 43.46 2.00e-46 179.00
IUUC-Hvu-047100 Hordeum vulgare 32.65 3.00e-04 36.60
IUUC-Kpa-049384 Komagataella pastoris 34.14 8.00e-70 255.00
IUUC-Lch-049950 Latimeria chalumnae 44.10 4.00e-47 181.00
IUUC-Lpe-050738 Leersia perrieri 32.65 2.00e-04 37.00
IUUC-Loc-051972 Lepisosteus oculatus 43.40 3.00e-47 182.00
IUUC-Lma-053190 Leptosphaeria maculans 32.48 3.00e-53 202.00
IUUC-Laf-053939 Loxodonta africana 43.46 1.00e-46 180.00
IUUC-Mcc-054600 Macaca mulatta 43.46 2.00e-46 179.00
IUUC-Meu-056259 Macropus eugenii 40.29 1.00e-46 179.00
IUUC-Mtr-058517 Medicago truncatula 30.16 3.00e-04 36.60
IUUC-Mla-058890 Melampsora laricipopulina 44.08 3.00e-51 192.00
IUUC-Mga-059549 Meleagris gallopavo 39.92 9.00e-50 190.00
IUUC-Mvi-060481 Microbotryum violaceum 28.72 1.00e-48 187.00
IUUC-Mmr-060865 Microcebus murinus 43.46 2.00e-46 179.00
IUUC-Mdo-062567 Monodelphis domestica 40.68 9.00e-47 180.00
IUUC-Mmu-063782 Mus musculus 40.15 8.00e-47 180.00
IUUC-Mac-064462 Musa acuminata 32.65 9.00e-05 38.50
IUUC-Mpu-066055 Mustela putorius furo 43.46 2.00e-46 179.00
IUUC-Mlu-067228 Myotis lucifugus 43.46 1.00e-46 179.00
IUUC-Nfi-068537 Neosartorya fischeri 30.08 3.00e-55 209.00
IUUC-Nle-069668 Nomascus leucogenys 43.46 2.00e-46 179.00
IUUC-Opr-070225 Ochotona princeps 43.88 7.00e-47 180.00
IUUC-Ont-071349 Oreochromis niloticus 43.04 1.00e-51 196.00
IUUC-Oan-073668 Ornithorhynchus anatinus 40.55 1.00e-43 168.00
IUUC-Ocu-074710 Oryctolagus cuniculus 43.46 2.00e-46 179.00
IUUC-Ogl-077821 Oryza glaberrima 32.65 5.00e-04 36.20
IUUC-Oin-079801 Oryza indica 32.65 3.00e-04 37.00
IUUC-Olo-080963 Oryza longistaminata 33.33 4.00e-04 36.20
IUUC-Ome-082006 Oryza meridionalis 32.65 5.00e-04 36.20
IUUC-Oni-082314 Oryza nivara 32.65 3.00e-04 37.00
IUUC-Oru-085108 Oryza rufipogon 32.65 2.00e-04 37.00
IUUC-Osa-085794 Oryza sativa 32.65 6.00e-04 35.80
IUUC-Ola-087410 Oryzias latipes 33.53 2.00e-52 199.00
IUUC-Oga-088644 Otolemur garnettii 43.46 2.00e-46 179.00
IUUC-Oar-089193 Ovis aries 43.04 5.00e-46 177.00
IUUC-Ptr-091523 Pan troglodytes 43.46 2.00e-46 179.00
IUUC-Pan-092415 Papio anubis 43.46 2.00e-46 179.00
IUUC-Psi-093114 Pelodiscus sinensis 39.49 2.00e-49 188.00
IUUC-Pma-094621 Petromyzon marinus 28.81 4.00e-46 176.00
IUUC-Pno-094984 Phaeosphaeria nodorum 31.36 7.00e-52 197.00
IUUC-Ppa-095609 Physcomitrella patens 37.56 2.00e-39 154.00
IUUC-Pfo-096695 Poecilia formosa 37.81 5.00e-52 197.00
IUUC-Pab-097907 Pongo abelii 44.30 5.00e-49 188.00
IUUC-Pop-099768 Populus trichocarpa 32.65 3.00e-04 36.60
IUUC-Pca-100628 Procavia capensis 47.37 2.00e-40 159.00
IUUC-Ppe-101390 Prunus persica 32.65 3.00e-04 36.60
IUUC-Pva-102416 Pteropus vampyrus 43.46 2.00e-46 179.00
IUUC-Pgr-103554 Puccinia graminis 40.43 2.00e-50 191.00
IUUC-Ptt-103859 Puccinia triticina 45.42 3.00e-51 194.00
IUUC-Pte-104241 Pyrenophora teres 41.80 2.00e-50 192.00
IUUC-Pyt-104741 Pyrenophora triticirepentis 30.60 2.00e-50 192.00
IUUC-Rno-105814 Rattus norvegicus 43.46 2.00e-46 179.00
IUUC-Sha-106693 Sarcophilus harrisii 40.15 2.00e-46 179.00
IUUC-Sja-107763 Schizosaccharomyces japonicus 31.85 2.00e-32 132.00
IUUC-Spo-108120 Schizosaccharomyces pombe 31.34 4.00e-35 141.00
IUUC-Smo-109024 Selaginella moellendorffii 36.65 5.00e-38 150.00
IUUC-Sit-110440 Setaria italica 33.33 5.00e-05 37.70
IUUC-Sly-111524 Solanum lycopersicum 31.75 4.00e-05 39.70
IUUC-Stu-112184 Solanum tuberosum 32.65 3.00e-04 37.00
IUUC-Sar-113568 Sorex araneus 42.62 1.00e-44 173.00
IUUC-Sre-115112 Sporisorium reilianum 40.16 9.00e-49 186.00
IUUC-Ssc-115432 Sus scrofa 39.78 2.00e-46 177.00
IUUC-Tgu-117298 Taeniopygia guttata 39.54 1.00e-48 186.00
IUUC-Tru-118423 Takifugu rubripes 39.64 5.00e-52 197.00
IUUC-Tsy-119214 Tarsius syrichta 30.43 5.00e-47 181.00
IUUC-Tni-120753 Tetraodon nigroviridis 43.88 4.00e-52 197.00
IUUC-Tca-121204 Theobroma cacao 32.65 2.00e-04 37.00
IUUC-Tme-127054 Tuber melanosporum 39.10 3.00e-52 198.00
IUUC-Tbe-128138 Tupaia belangeri 35.92 7.00e-44 170.00
IUUC-Ttr-129014 Tursiops truncatus 38.50 3.00e-34 138.00
IUUC-Uma-129458 Ustilago maydis 41.15 3.00e-50 191.00
IUUC-Vpa-130655 Vicugna pacos 39.15 7.00e-39 154.00
IUUC-Vvi-131738 Vitis vinifera 30.16 2.00e-04 37.40
IUUC-Xtr-131839 Xenopus tropicalis 39.78 3.00e-51 194.00
IUUC-Xma-133499 Xiphophorus maculatus 42.26 3.00e-51 195.00
IUUC-Yli-134626 Yarrowia lipolytica 35.76 2.00e-65 241.00
Created Date 25-Jun-2017

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