iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000000868.5	ENSGALT00000001279.5	ENSGALP00000001277.5
ENSGALG00000000868.5	ENSGALT00000083094.1	ENSGALP00000049809.1
ENSGALG00000000868.5	ENSGALT00000060721.1	ENSGALP00000047675.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.60e-07	32.1	193	243

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..........kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C + +          ++ ++ l+C+Hvfh+ C+  w    +   k+++CP+C+
   Q: 193  CAVCGQQIfvdvneegiiEN-TYRLSCNHVFHEFCIRGW----CIVGKKQTCPYCK 243
           9***9988888887777655.777***************....889999******7 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MVEHALMHAK HHGHEAMHAE MVLILIATLV VAQLLLVQWK QRHPRSYNMV TLFQMWVVPL 60
YFTIKLYWWR FLVIWVLFSA VTAFVTFKAT RKPLVQTTPR LVYKWFLLIY KMSYATGIVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGGAAA CCACAGGTGT CAGCAGAGAA CCGCTCTGTG GCCATCCCTT GTTGCGGGTT 60
GCACGGAGCT GGGGTTGTAC AAGCTTAGCT GGGGTGGGCT GGCTGATCTA TGGCCTCCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002350	Ailuropoda melanoleuca	95.56	1.00e-160	558.00
IUUC-Apl-003882	Anas platyrhynchos	87.90	7.00e-135	473.00
IUUC-Aca-004343	Anolis carolinensis	91.30	3.00e-23	99.00
IUUC-Ame-010680	Astyanax mexicanus	88.05	1.00e-149	521.00
IUUC-Bta-013045	Bos taurus	96.25	2.00e-161	560.00
IUUC-Bci-013624	Botrytis cinerea	38.18	2.00e-07	50.80
IUUC-Cel-018296	Caenorhabditis elegans	51.63	1.00e-94	339.00
IUUC-Cja-019866	Callithrix jacchus	95.90	3.00e-161	560.00
IUUC-Cfa-021176	Canis familiaris	95.92	6.00e-160	556.00
IUUC-Cpo-022268	Cavia porcellus	95.22	7.00e-159	552.00
IUUC-Cre-022649	Chlamydomonas reinhardtii	41.83	9.00e-55	206.00
IUUC-Csa-023727	Chlorocebus sabaeus	96.59	1.00e-161	561.00
IUUC-Cho-025016	Choloepus hoffmanni	95.90	4.00e-161	560.00
IUUC-Cin-025281	Ciona intestinalis	65.99	3.00e-123	434.00
IUUC-Csv-026338	Ciona savignyi	63.29	1.00e-112	399.00
IUUC-Dre-027836	Danio rerio	82.25	9.00e-134	469.00
IUUC-Dno-029737	Dasypus novemcinctus	94.61	3.00e-159	553.00
IUUC-Dor-031070	Dipodomys ordii	84.30	1.00e-141	495.00
IUUC-Dme-031867	Drosophila melanogaster	60.96	5.00e-109	387.00
IUUC-Ete-032964	Echinops telfairi	86.69	1.00e-150	525.00
IUUC-Eca-034398	Equus caballus	96.59	2.00e-161	561.00
IUUC-Eeu-035318	Erinaceus europaeus	65.75	1.00e-111	395.00
IUUC-Fca-035807	Felis catus	96.26	4.00e-160	556.00
IUUC-Fal-036721	Ficedula albicollis	96.88	4.00e-159	553.00
IUUC-Gmo-039699	Gadus morhua	88.40	2.00e-140	491.00
IUUC-Gac-042639	Gasterosteus aculeatus	86.69	4.00e-139	486.00
IUUC-Ggo-045576	Gorilla gorilla	96.25	4.00e-161	560.00
IUUC-Hsa-046468	Homo sapiens	96.25	3.00e-161	560.00
IUUC-Itr-048638	Ictidomys tridecemlineatus	95.93	7.00e-144	502.00
IUUC-Lch-050207	Latimeria chalumnae	82.37	1.00e-136	478.00
IUUC-Loc-052172	Lepisosteus oculatus	89.08	5.00e-151	526.00
IUUC-Laf-053879	Loxodonta africana	95.90	4.00e-161	560.00
IUUC-Mcc-055492	Macaca mulatta	96.59	1.00e-161	561.00
IUUC-Meu-055976	Macropus eugenii	81.23	3.00e-128	450.00
IUUC-Mga-059989	Meleagris gallopavo	98.98	8.00e-164	568.00
IUUC-Mmr-060894	Microcebus murinus	96.59	1.00e-161	561.00
IUUC-Mdo-061826	Monodelphis domestica	95.90	4.00e-158	550.00
IUUC-Mmu-063717	Mus musculus	96.25	4.00e-161	560.00
IUUC-Mpu-066826	Mustela putorius furo	96.25	2.00e-161	561.00
IUUC-Mlu-068081	Myotis lucifugus	93.96	2.00e-157	547.00
IUUC-Nle-069734	Nomascus leucogenys	96.59	1.00e-161	561.00
IUUC-Opr-070379	Ochotona princeps	96.25	1.00e-160	558.00
IUUC-Ont-071855	Oreochromis niloticus	86.69	7.00e-139	486.00
IUUC-Ocu-074363	Oryctolagus cuniculus	96.25	8.00e-161	559.00
IUUC-Ola-086489	Oryzias latipes	85.67	2.00e-137	481.00
IUUC-Oga-088323	Otolemur garnettii	96.26	4.00e-160	556.00
IUUC-Oar-090243	Ovis aries	95.90	6.00e-161	559.00
IUUC-Ptr-091374	Pan troglodytes	96.25	3.00e-161	560.00
IUUC-Pan-092115	Papio anubis	96.59	1.00e-161	561.00
IUUC-Psi-093658	Pelodiscus sinensis	96.60	2.00e-150	524.00
IUUC-Pfo-097261	Poecilia formosa	86.01	1.00e-137	481.00
IUUC-Pab-098579	Pongo abelii	96.25	3.00e-161	560.00
IUUC-Pca-100119	Procavia capensis	91.47	5.00e-147	513.00
IUUC-Pva-102111	Pteropus vampyrus	96.59	2.00e-161	561.00
IUUC-Rno-105364	Rattus norvegicus	96.25	4.00e-161	560.00
IUUC-Sha-107005	Sarcophilus harrisii	96.25	1.00e-161	561.00
IUUC-Stu-112248	Solanum tuberosum	39.66	1.00e-06	47.80
IUUC-Sar-113163	Sorex araneus	96.25	2.00e-161	561.00
IUUC-Ssc-115633	Sus scrofa	95.58	2.00e-159	554.00
IUUC-Tgu-116869	Taeniopygia guttata	97.95	2.00e-162	564.00
IUUC-Tru-118217	Takifugu rubripes	85.14	3.00e-145	507.00
IUUC-Tsy-119308	Tarsius syrichta	95.90	1.00e-160	558.00
IUUC-Tni-119882	Tetraodon nigroviridis	85.52	4.00e-145	506.00
IUUC-Tbe-127912	Tupaia belangeri	71.54	4.00e-109	387.00
IUUC-Ttr-129087	Tursiops truncatus	96.25	2.00e-161	560.00
IUUC-Vpa-130785	Vicugna pacos	93.86	6.00e-157	546.00
IUUC-Xtr-132801	Xenopus tropicalis	94.88	2.00e-150	524.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence