iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071984

Ensembl Protein ID

ENSONIP00000022686.1

UniProt Accession

I3KNJ1; I3KNJ1_ORENI

Genbank Protein ID

ENSONIP00000022686

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01019334

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000018005.1	ENSONIT00000022706.1	ENSONIP00000022686.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	40.16	8.00e-72	268.00	IUUC-Hsa-046376
E3 activity/RING/RING	42.40	5.00e-46	182.00	IUUC-Mmu-063207
E3 activity/RING/RING	40.32	2.00e-72	270.00	IUUC-Rno-105641

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

TISFTMSADS DTNTWSAEDD NKLVRPKVEF CSLLQLAGAT KDVFTMKEVM FYLGQYIIQK 60
QLYDQKQQHI VHCAQDALGR VLGVDSFSVK EPRVLFAMIT KNLVAVRSPE STTSLSEPHS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAAACTGCT CAGATTGGAT GATTGGATGA TTAATGCTTT TATTGTTGTA TCTATCAGTG 60
TGTTTGGGGA TTTGAATTGA GAAACTGTCG GCTTCCTAGC CACTAGGGGC GCCATCTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR015459--MDM2_E3_ligase
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002039	Ailuropoda melanoleuca	40.16	7.00e-73	268.00
IUUC-Apl-003193	Anas platyrhynchos	44.08	2.00e-86	313.00
IUUC-Aca-004305	Anolis carolinensis	42.77	6.00e-52	198.00
IUUC-Ame-010675	Astyanax mexicanus	51.52	6.00e-100	358.00
IUUC-Bta-013270	Bos taurus	41.82	8.00e-73	267.00
IUUC-Cja-019744	Callithrix jacchus	42.47	4.00e-74	272.00
IUUC-Cfa-020807	Canis familiaris	40.63	4.00e-67	248.00
IUUC-Cpo-022182	Cavia porcellus	41.40	6.00e-75	275.00
IUUC-Csa-023541	Chlorocebus sabaeus	40.37	5.00e-75	275.00
IUUC-Cin-025448	Ciona intestinalis	30.26	2.00e-14	72.80
IUUC-Csv-026151	Ciona savignyi	30.85	1.00e-11	63.20
IUUC-Dre-028419	Danio rerio	49.54	6.00e-60	224.00
IUUC-Dno-028950	Dasypus novemcinctus	40.08	2.00e-72	266.00
IUUC-Dor-031048	Dipodomys ordii	47.21	6.00e-43	168.00
IUUC-Ete-032264	Echinops telfairi	43.36	1.00e-48	187.00
IUUC-Eca-033301	Equus caballus	40.73	2.00e-74	273.00
IUUC-Eeu-035005	Erinaceus europaeus	39.41	1.00e-40	160.00
IUUC-Fca-035454	Felis catus	40.40	9.00e-73	267.00
IUUC-Fal-036720	Ficedula albicollis	57.94	1.00e-28	120.00
IUUC-Gmo-039296	Gadus morhua	54.05	9.00e-58	217.00
IUUC-Gga-040251	Gallus gallus	43.75	4.00e-86	312.00
IUUC-Gac-041528	Gasterosteus aculeatus	67.43	4.00e-61	228.00
IUUC-Ggo-044948	Gorilla gorilla	40.84	4.00e-49	189.00
IUUC-Hsa-046376	Homo sapiens	40.37	4.00e-75	275.00
IUUC-Itr-048328	Ictidomys tridecemlineatus	41.27	1.00e-75	277.00
IUUC-Lch-050037	Latimeria chalumnae	44.76	9.00e-77	280.00
IUUC-Loc-051837	Lepisosteus oculatus	51.35	3.00e-107	382.00
IUUC-Laf-053483	Loxodonta africana	40.64	4.00e-80	292.00
IUUC-Mcc-055294	Macaca mulatta	40.37	4.00e-75	275.00
IUUC-Mga-060007	Meleagris gallopavo	43.42	3.00e-84	305.00
IUUC-Mmr-060673	Microcebus murinus	41.83	4.00e-80	292.00
IUUC-Mdo-063057	Monodelphis domestica	45.81	9.00e-59	221.00
IUUC-Mmu-063207	Mus musculus	39.92	2.00e-71	263.00
IUUC-Mpu-065836	Mustela putorius furo	42.33	7.00e-79	288.00
IUUC-Mlu-068193	Myotis lucifugus	41.20	1.00e-73	270.00
IUUC-Nle-069927	Nomascus leucogenys	40.61	1.00e-74	274.00
IUUC-Opr-070590	Ochotona princeps	39.28	8.00e-65	241.00
IUUC-Oan-072744	Ornithorhynchus anatinus	43.18	5.00e-80	291.00
IUUC-Ocu-074071	Oryctolagus cuniculus	42.81	3.00e-49	190.00
IUUC-Ola-087329	Oryzias latipes	62.81	1.00e-84	307.00
IUUC-Oga-088135	Otolemur garnettii	45.14	1.00e-47	184.00
IUUC-Oar-089726	Ovis aries	40.66	3.00e-73	269.00
IUUC-Ptr-091399	Pan troglodytes	40.61	9.00e-75	274.00
IUUC-Pan-092720	Papio anubis	40.37	4.00e-75	275.00
IUUC-Psi-093591	Pelodiscus sinensis	40.30	3.00e-49	189.00
IUUC-Pma-094500	Petromyzon marinus	67.86	4.00e-19	87.80
IUUC-Pfo-096316	Poecilia formosa	66.87	8.00e-89	320.00
IUUC-Pab-097696	Pongo abelii	41.55	9.00e-75	274.00
IUUC-Pca-100974	Procavia capensis	40.84	1.00e-79	290.00
IUUC-Pva-102488	Pteropus vampyrus	36.93	3.00e-62	232.00
IUUC-Rno-105641	Rattus norvegicus	39.24	7.00e-75	274.00
IUUC-Sha-107314	Sarcophilus harrisii	43.93	1.00e-87	317.00
IUUC-Sar-112938	Sorex araneus	39.29	3.00e-67	249.00
IUUC-Ssc-115495	Sus scrofa	40.80	1.00e-74	273.00
IUUC-Tgu-116623	Taeniopygia guttata	42.74	3.00e-86	312.00
IUUC-Tru-117820	Takifugu rubripes	69.18	1.00e-93	337.00
IUUC-Tni-119793	Tetraodon nigroviridis	58.20	1.00e-70	260.00
IUUC-Tbe-127816	Tupaia belangeri	38.36	2.00e-43	169.00
IUUC-Ttr-129194	Tursiops truncatus	41.83	4.00e-46	179.00
IUUC-Vpa-130326	Vicugna pacos	39.70	4.00e-68	252.00
IUUC-Xtr-132216	Xenopus tropicalis	41.88	2.00e-79	289.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence