iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Rno-105964

Ensembl Protein ID

ENSRNOP00000019454.5

UniProt Accession

G3V7V1; G3V7V1_RAT

Genbank Protein ID

ENSRNOP00000019454

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AABR07026560

Gene Name

Ing1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000014520.7	ENSRNOT00000019454.7	ENSRNOP00000019454.5

Annotation

mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.50e-09	36.7	166	213

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 166  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 213
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

EILKELDDYY EKFKRETDST QKRRVLHCIQ RALIRSQELG DEKIQIVSQM VELVENRSRQ 60
VDSHVELFEA HQDISDGTGG GGKAGQDKSK SEAITQADKP NNKRSRRQRN NENRENASNN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGATCCTGA AGGAGTTGGA TGACTACTAT GAGAAGTTCA AGCGGGAGAC GGACAGCACC 60
CAGAAGAGGC GGGTGCTGCA CTGCATCCAG AGGGCCCTGA TCCGAAGCCA GGAGCTGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	93.16	2.00e-98	352.00
IUUC-Apl-003910	Anas platyrhynchos	91.42	8.00e-95	340.00
IUUC-Aca-004874	Anolis carolinensis	91.45	5.00e-95	340.00
IUUC-Aly-005815	Arabidopsis lyrata	80.00	2.00e-28	119.00
IUUC-Ath-006765	Arabidopsis thaliana	76.36	2.00e-27	115.00
IUUC-Acl-008091	Aspergillus clavatus	52.11	1.00e-18	88.20
IUUC-Ame-011262	Astyanax mexicanus	68.16	2.00e-76	278.00
IUUC-Bta-013507	Bos taurus	88.03	3.00e-89	321.00
IUUC-Cja-018925	Callithrix jacchus	87.61	9.00e-92	329.00
IUUC-Cfa-020947	Canis familiaris	93.59	3.00e-98	351.00
IUUC-Cpo-022286	Cavia porcellus	91.88	8.00e-96	343.00
IUUC-Csa-023825	Chlorocebus sabaeus	87.18	2.00e-91	328.00
IUUC-Cho-024577	Choloepus hoffmanni	93.99	9.00e-99	352.00
IUUC-Cne-027005	Cryptococcus neoformans	45.95	7.00e-16	78.20
IUUC-Dno-029834	Dasypus novemcinctus	94.02	9.00e-100	356.00
IUUC-Dor-030315	Dipodomys ordii	91.03	2.00e-108	385.00
IUUC-Ete-032408	Echinops telfairi	90.13	6.00e-92	330.00
IUUC-Eca-034244	Equus caballus	93.59	3.00e-99	353.00
IUUC-Fca-035391	Felis catus	90.83	4.00e-89	320.00
IUUC-Fal-036838	Ficedula albicollis	90.60	6.00e-95	340.00
IUUC-Fox-037925	Fusarium oxysporum	64.71	2.00e-19	90.50
IUUC-Gga-040619	Gallus gallus	91.03	1.00e-94	338.00
IUUC-Gac-041996	Gasterosteus aculeatus	61.11	1.00e-74	272.00
IUUC-Ggo-045481	Gorilla gorilla	87.61	4.00e-92	331.00
IUUC-Hsa-046170	Homo sapiens	87.61	5.00e-92	331.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	94.02	2.00e-98	351.00
IUUC-Lch-050397	Latimeria chalumnae	86.75	7.00e-92	330.00
IUUC-Loc-052038	Lepisosteus oculatus	80.82	4.00e-80	290.00
IUUC-Laf-054126	Loxodonta africana	94.87	2.00e-100	358.00
IUUC-Mcc-055031	Macaca mulatta	86.75	2.00e-91	328.00
IUUC-Meu-056248	Macropus eugenii	92.70	3.00e-96	344.00
IUUC-Mga-059217	Meleagris gallopavo	90.99	7.00e-94	336.00
IUUC-Mmr-061581	Microcebus murinus	94.87	4.00e-100	357.00
IUUC-Mdo-062452	Monodelphis domestica	92.31	9.00e-97	346.00
IUUC-Mmu-063412	Mus musculus	99.15	3.00e-103	367.00
IUUC-Mpu-066479	Mustela putorius furo	93.16	2.00e-98	352.00
IUUC-Mlu-067723	Myotis lucifugus	93.16	2.00e-98	352.00
IUUC-Nle-069122	Nomascus leucogenys	87.61	1.00e-91	329.00
IUUC-Opr-070835	Ochotona princeps	84.12	7.00e-86	309.00
IUUC-Oan-073023	Ornithorhynchus anatinus	90.60	3.00e-92	331.00
IUUC-Ocu-073779	Oryctolagus cuniculus	92.31	3.00e-96	344.00
IUUC-Ola-086891	Oryzias latipes	63.68	3.00e-76	278.00
IUUC-Oga-087954	Otolemur garnettii	94.02	7.00e-99	353.00
IUUC-Oar-090006	Ovis aries	88.46	1.00e-94	338.00
IUUC-Ptr-090589	Pan troglodytes	88.03	3.00e-92	331.00
IUUC-Pan-091896	Papio anubis	86.75	2.00e-91	329.00
IUUC-Psi-093266	Pelodiscus sinensis	91.88	2.00e-96	345.00
IUUC-Pma-094265	Petromyzon marinus	73.97	6.00e-33	132.00
IUUC-Pab-098253	Pongo abelii	88.03	3.00e-92	331.00
IUUC-Pva-102753	Pteropus vampyrus	88.46	1.00e-87	316.00
IUUC-Sha-107270	Sarcophilus harrisii	91.45	8.00e-96	343.00
IUUC-Tgu-116822	Taeniopygia guttata	91.88	1.00e-95	342.00
IUUC-Tni-119980	Tetraodon nigroviridis	57.85	9.00e-71	259.00
IUUC-Tvi-122341	Trichoderma virens	62.50	4.00e-16	77.00
IUUC-Ttr-128672	Tursiops truncatus	90.17	3.00e-97	347.00
IUUC-Xtr-132200	Xenopus tropicalis	83.33	3.00e-88	317.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence