iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xtr-132200

Ensembl Protein ID

ENSXETP00000018004.3

UniProt Accession

A4IGN5; A4IGN5_XENTR

Genbank Protein ID

AAI35182.1

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AAMC01018087

Gene Name

ing1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000008212.4	ENSXETT00000018004.3	ENSXETP00000018004.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.40e-08	35.0	211	258

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+Cp+Cr 
   Q: 211  TYC-LCNQVSYGE--MIGCDNeeCPiEWFHFSCVGLN---HKPKGK-WYCPECRG 258
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MLSPANGEHI HMVNYVEDYL DSIESLPFDL QRNVSLMREI DAKYQEILKE LDDYYEKFKR 60
ESDSGQKKRL LQFIQRALIR SQELGDDKIQ IVSQMVELVE NRTRQVDSHV ELFETCQDLN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATAGACAGC CATTCAATCA GCTGCTGCAC TTTTTTTCTC TTTCCACACA GCCCCAATCC 60
GCAGCTCCCC GCACACTCTC CCTCGCATCT CCATGCACCT CATGCCAGGA TCACCCCGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0010941--P:regulation of cell death

KEGG

xtr:100037882

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	85.66	7.00e-118	416.00
IUUC-Apl-003910	Anas platyrhynchos	86.33	2.00e-119	421.00
IUUC-Aca-004874	Anolis carolinensis	85.00	8.00e-117	412.00
IUUC-Aly-005815	Arabidopsis lyrata	81.82	6.00e-29	120.00
IUUC-Ath-006765	Arabidopsis thaliana	78.18	4.00e-28	117.00
IUUC-Ate-010297	Aspergillus terreus	63.64	6.00e-19	89.40
IUUC-Ame-011262	Astyanax mexicanus	63.79	3.00e-91	327.00
IUUC-Bta-013507	Bos taurus	81.62	7.00e-84	302.00
IUUC-Cja-018925	Callithrix jacchus	83.51	3.00e-115	407.00
IUUC-Cfa-020947	Canis familiaris	86.38	2.00e-117	415.00
IUUC-Cpo-022286	Cavia porcellus	82.20	3.00e-90	324.00
IUUC-Csa-023825	Chlorocebus sabaeus	83.15	7.00e-115	406.00
IUUC-Cho-024577	Choloepus hoffmanni	83.26	2.00e-89	321.00
IUUC-Dno-029834	Dasypus novemcinctus	87.10	8.00e-120	422.00
IUUC-Dor-030315	Dipodomys ordii	82.05	1.00e-97	349.00
IUUC-Ete-032408	Echinops telfairi	80.43	9.00e-85	306.00
IUUC-Eca-034244	Equus caballus	83.33	2.00e-90	324.00
IUUC-Fca-035391	Felis catus	80.69	4.00e-99	353.00
IUUC-Fal-036838	Ficedula albicollis	85.66	2.00e-119	421.00
IUUC-Gga-040619	Gallus gallus	86.38	1.00e-119	422.00
IUUC-Gac-041996	Gasterosteus aculeatus	62.86	5.00e-94	337.00
IUUC-Ggo-045481	Gorilla gorilla	80.08	7.00e-89	320.00
IUUC-Hsa-046170	Homo sapiens	80.08	6.00e-89	320.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	85.04	1.00e-92	332.00
IUUC-Lch-050397	Latimeria chalumnae	86.02	4.00e-119	420.00
IUUC-Loc-052038	Lepisosteus oculatus	77.91	3.00e-96	344.00
IUUC-Laf-054126	Loxodonta africana	86.02	2.00e-118	418.00
IUUC-Mcc-055031	Macaca mulatta	80.43	2.00e-88	319.00
IUUC-Meu-056248	Macropus eugenii	84.03	2.00e-93	335.00
IUUC-Mga-059217	Meleagris gallopavo	84.55	4.00e-92	330.00
IUUC-Mmr-061581	Microcebus murinus	84.36	1.00e-96	345.00
IUUC-Mdo-062452	Monodelphis domestica	87.10	2.00e-120	424.00
IUUC-Mmu-063412	Mus musculus	85.30	2.00e-117	414.00
IUUC-Mpu-066479	Mustela putorius furo	83.76	4.00e-91	327.00
IUUC-Mlu-067586	Myotis lucifugus	72.95	2.00e-108	384.00
IUUC-Nle-069122	Nomascus leucogenys	82.80	3.00e-114	404.00
IUUC-Opr-070835	Ochotona princeps	78.11	3.00e-78	284.00
IUUC-Ont-071606	Oreochromis niloticus	58.17	1.00e-87	316.00
IUUC-Oan-073023	Ornithorhynchus anatinus	86.02	4.00e-118	417.00
IUUC-Ocu-073779	Oryctolagus cuniculus	80.00	9.00e-87	312.00
IUUC-Ogl-077118	Oryza glaberrima	33.33	4.00e-32	131.00
IUUC-Oin-079049	Oryza indica	64.38	6.00e-28	117.00
IUUC-Ome-081291	Oryza meridionalis	33.33	2.00e-32	132.00
IUUC-Oni-082218	Oryza nivara	64.38	6.00e-28	117.00
IUUC-Osa-085563	Oryza sativa	33.33	2.00e-32	132.00
IUUC-Ola-086891	Oryzias latipes	65.00	5.00e-95	340.00
IUUC-Olu-087851	Ostreococcus lucimarinus	67.31	2.00e-19	88.20
IUUC-Oga-087954	Otolemur garnettii	83.51	2.00e-115	408.00
IUUC-Oar-090006	Ovis aries	83.87	6.00e-114	403.00
IUUC-Ptr-090589	Pan troglodytes	83.15	6.00e-115	406.00
IUUC-Pan-091896	Papio anubis	80.43	1.00e-88	320.00
IUUC-Psi-093266	Pelodiscus sinensis	87.46	6.00e-121	426.00
IUUC-Pma-094265	Petromyzon marinus	76.39	3.00e-33	133.00
IUUC-Pab-098253	Pongo abelii	83.15	1.00e-114	405.00
IUUC-Pop-099415	Populus trichocarpa	76.36	5.00e-26	110.00
IUUC-Pva-102753	Pteropus vampyrus	74.52	1.00e-80	293.00
IUUC-Rno-105964	Rattus norvegicus	83.33	3.00e-84	304.00
IUUC-Sha-107270	Sarcophilus harrisii	87.10	5.00e-120	423.00
IUUC-Sre-115124	Sporisorium reilianum	46.67	1.00e-21	98.20
IUUC-Tgu-116822	Taeniopygia guttata	86.38	4.00e-120	423.00
IUUC-Tru-118168	Takifugu rubripes	53.58	3.00e-70	257.00
IUUC-Tni-119980	Tetraodon nigroviridis	55.70	7.00e-80	290.00
IUUC-Tre-121950	Trichoderma reesei	64.29	5.00e-20	93.20
IUUC-Ttr-128672	Tursiops truncatus	81.70	1.00e-88	319.00
IUUC-Zma-135298	Zea mays	67.80	1.00e-23	103.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence