iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055796

Ensembl Protein ID

ENSMMUP00000045621.1

UniProt Accession

G7MYA3; G7MYA3_MACMU

Genbank Protein ID

AFE65373.1; AFH31550.1; AFI34516.1; EHH27958.1

Protein Name

Zinc finger and BTB domain-containing protein 1 isoform 1

Genbank Nucleotide ID

JSUE03039895; JU474746; JV044445; CM001259

Gene Name

ZBTB1; EGK_18283

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000004748.3	ENSMMUT00000067298.1	ENSMMUP00000055619.1
ENSMMUG00000004748.3	ENSMMUT00000070092.1	ENSMMUP00000045621.1
ENSMMUG00000004748.3	ENSMMUT00000006711.3	ENSMMUP00000032869.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.50e-12	48.8	24	87

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalf.lmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +D+++ +++ +f+ahk+vLaa+Ss+F+  f +++ +  +  +  ++k +++e+f  +l+F+Y gk+
   Q: 24   CDCCIAIDDIYFQAHKAVLAACSSYFRMFFmNHQHSTAQ-LNLSNMK-ISAECFDLILQFMYLGKI 87
           8*************************9999333333333.5555666.****************97 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAKPSHSSYV LQQLNNQREW GFLCDCCIAI DDIYFQAHKA VLAACSSYFR MFFMNHQHST 60
AQLNLSNMKI SAECFDLILQ FMYLGKIMTA PSSFEQFKVA MNYLQLYNVP DCLEDIQDAD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGAGCG CGGGGACTAG GCGACCCTGA ACCGACCGGA CAGAGCGAGG TTTCCGAAGC 60
ACTCCAGGCG GACCGCGAGG GACGGCCCAG CTGCTGGGCC CAACGGGGCA GGGGTCTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR000877--Prot_inh_BBI
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0016604--C:nuclear body
GO:0031965--C:nuclear membrane
GO:0046872--F:metal ion binding
GO:0003676--F:nucleic acid binding
GO:0030183--P:B cell differentiation
GO:0034644--P:cellular response to UV
GO:0006338--P:chromatin remodeling
GO:0042789--P:mRNA transcription from RNA polymerase II promoter
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0032825--P:positive regulation of natural killer cell differentiation
GO:2000176--P:positive regulation of pro-T cell differentiation
GO:0002711--P:positive regulation of T cell mediated immunity
GO:0051260--P:protein homooligomerization
GO:0033077--P:T cell differentiation in thymus
GO:0048538--P:thymus development
GO:0019985--P:translesion synthesis

KEGG

mcc:710277

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001844	Ailuropoda melanoleuca	96.77	0.00e+00	1350.00
IUUC-Apl-003725	Anas platyrhynchos	82.55	0.00e+00	1138.00
IUUC-Aca-004672	Anolis carolinensis	72.06	0.00e+00	953.00
IUUC-Ame-011859	Astyanax mexicanus	48.57	1.00e-178	620.00
IUUC-Bta-013323	Bos taurus	97.62	0.00e+00	1409.00
IUUC-Cja-018727	Callithrix jacchus	98.88	0.00e+00	1374.00
IUUC-Cfa-020390	Canis familiaris	97.05	0.00e+00	1358.00
IUUC-Cpo-022434	Cavia porcellus	96.35	0.00e+00	1387.00
IUUC-Csa-023909	Chlorocebus sabaeus	100.00	0.00e+00	1191.00
IUUC-Cho-024288	Choloepus hoffmanni	96.09	0.00e+00	947.00
IUUC-Dre-027623	Danio rerio	47.64	7.00e-179	620.00
IUUC-Dno-029224	Dasypus novemcinctus	97.62	0.00e+00	1407.00
IUUC-Ete-032672	Echinops telfairi	93.06	0.00e+00	988.00
IUUC-Eca-034361	Equus caballus	98.10	0.00e+00	1196.00
IUUC-Eeu-035254	Erinaceus europaeus	90.16	2.00e-157	549.00
IUUC-Fca-036217	Felis catus	96.77	0.00e+00	1394.00
IUUC-Fal-037026	Ficedula albicollis	78.47	0.00e+00	962.00
IUUC-Gga-040550	Gallus gallus	77.08	3.00e-143	501.00
IUUC-Gac-041379	Gasterosteus aculeatus	46.55	3.00e-170	592.00
IUUC-Ggo-044852	Gorilla gorilla	99.16	0.00e+00	1422.00
IUUC-Hsa-046418	Homo sapiens	99.02	0.00e+00	1420.00
IUUC-Itr-048065	Ictidomys tridecemlineatus	97.05	0.00e+00	1392.00
IUUC-Lch-050025	Latimeria chalumnae	56.06	0.00e+00	785.00
IUUC-Loc-052590	Lepisosteus oculatus	50.55	0.00e+00	652.00
IUUC-Laf-054526	Loxodonta africana	96.63	0.00e+00	1377.00
IUUC-Mga-059889	Meleagris gallopavo	81.72	0.00e+00	1149.00
IUUC-Mmr-061304	Microcebus murinus	97.90	0.00e+00	1364.00
IUUC-Mdo-062964	Monodelphis domestica	88.92	0.00e+00	1279.00
IUUC-Mmu-064268	Mus musculus	94.40	0.00e+00	1350.00
IUUC-Mpu-065817	Mustela putorius furo	95.57	0.00e+00	1169.00
IUUC-Mlu-068225	Myotis lucifugus	97.62	0.00e+00	1382.00
IUUC-Nle-069390	Nomascus leucogenys	99.02	0.00e+00	1419.00
IUUC-Opr-070274	Ochotona princeps	95.65	0.00e+00	1337.00
IUUC-Ont-072145	Oreochromis niloticus	45.99	1.00e-171	596.00
IUUC-Oan-073144	Ornithorhynchus anatinus	85.23	0.00e+00	1030.00
IUUC-Ocu-074835	Oryctolagus cuniculus	89.62	0.00e+00	1239.00
IUUC-Ola-087520	Oryzias latipes	46.92	1.00e-169	590.00
IUUC-Oga-088605	Otolemur garnettii	96.91	0.00e+00	1389.00
IUUC-Oar-089788	Ovis aries	97.62	0.00e+00	1409.00
IUUC-Ptr-091274	Pan troglodytes	99.02	0.00e+00	1420.00
IUUC-Psi-093560	Pelodiscus sinensis	80.28	0.00e+00	1013.00
IUUC-Pfo-097221	Poecilia formosa	46.09	2.00e-168	586.00
IUUC-Pab-097799	Pongo abelii	99.05	0.00e+00	1249.00
IUUC-Pva-102769	Pteropus vampyrus	97.34	0.00e+00	1362.00
IUUC-Rno-105959	Rattus norvegicus	91.31	0.00e+00	1159.00
IUUC-Sha-106613	Sarcophilus harrisii	88.92	0.00e+00	1271.00
IUUC-Sar-112951	Sorex araneus	86.08	0.00e+00	1077.00
IUUC-Ssc-115673	Sus scrofa	97.62	0.00e+00	1360.00
IUUC-Tgu-116806	Taeniopygia guttata	80.47	0.00e+00	1107.00
IUUC-Tru-117544	Takifugu rubripes	43.53	2.00e-132	465.00
IUUC-Tsy-119233	Tarsius syrichta	90.74	0.00e+00	1239.00
IUUC-Tni-120273	Tetraodon nigroviridis	57.05	4.00e-101	362.00
IUUC-Tbe-128020	Tupaia belangeri	96.76	0.00e+00	1194.00
IUUC-Ttr-128357	Tursiops truncatus	97.76	0.00e+00	1352.00
IUUC-Vpa-130487	Vicugna pacos	97.62	0.00e+00	1408.00
IUUC-Xtr-132415	Xenopus tropicalis	58.22	0.00e+00	796.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence