iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-054981

Ensembl Protein ID

ENSMMUP00000053545.1

UniProt Accession

A0A1D5QZR2; A0A1D5QZR2_MACMU

Genbank Protein ID

ENSMMUP00000053545

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03015750

Gene Name

HIC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000048710.1	ENSMMUT00000062252.1	ENSMMUP00000053545.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	2.40e-12	48.1	28	87

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgkl 65
           +Dvi+vv++  f+ahk vLaasS ++++l  +        +  +++ d v+p vfr +l+F+Ytg+l
   Q: 28   CDVIIVVQNALFRAHKNVLAASSAYLKSLVVH-------DNLLNLDhDmVSPAVFRLVLDFIYTGRL 87
           9*****************************77.......4566677678****************98 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MLDTMEAPGH SRQLLLQLNN QRTKGFLCDV IIVVQNALFR AHKNVLAASS AYLKSLVVHD 60
NLLNLDHDMV SPAVFRLVLD FIYTGRLADG AEAAAAAAVA PGAEPSLGAV LAAASYLQIP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGCGGCGC GCCATTCGGG GTCCCCTTCC TCCCAGAAGA GACGTCACCC ACACAAACCT 60
GACCTTCACG TGGGGTGCGG GGCCTTGCGG GGTCCCAGCC GCAGGCGCCC CTGTTGTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR028424--HIC1
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0003676--F:nucleic acid binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	92.14	1.00e-152	533.00
IUUC-Aca-004680	Anolis carolinensis	73.96	3.00e-68	253.00
IUUC-Ame-010967	Astyanax mexicanus	60.24	1.00e-93	337.00
IUUC-Bta-013567	Bos taurus	97.64	3.00e-165	575.00
IUUC-Cja-019621	Callithrix jacchus	98.85	3.00e-42	163.00
IUUC-Cfa-020731	Canis familiaris	96.50	0.00e+00	863.00
IUUC-Cpo-021326	Cavia porcellus	93.42	0.00e+00	889.00
IUUC-Csa-023645	Chlorocebus sabaeus	100.00	0.00e+00	869.00
IUUC-Dre-028027	Danio rerio	57.64	2.00e-91	330.00
IUUC-Dno-028900	Dasypus novemcinctus	95.24	0.00e+00	867.00
IUUC-Fal-036980	Ficedula albicollis	56.05	1.00e-167	583.00
IUUC-Gga-040708	Gallus gallus	69.97	4.00e-105	375.00
IUUC-Ggo-044591	Gorilla gorilla	99.70	7.00e-140	490.00
IUUC-Hsa-046769	Homo sapiens	99.30	0.00e+00	852.00
IUUC-Itr-048627	Ictidomys tridecemlineatus	95.96	0.00e+00	880.00
IUUC-Lch-049412	Latimeria chalumnae	54.35	0.00e+00	631.00
IUUC-Loc-051883	Lepisosteus oculatus	63.47	6.00e-93	335.00
IUUC-Laf-053358	Loxodonta africana	94.29	2.00e-169	589.00
IUUC-Meu-056181	Macropus eugenii	72.51	1.00e-106	380.00
IUUC-Mga-059592	Meleagris gallopavo	72.85	4.00e-102	365.00
IUUC-Mmr-061560	Microcebus murinus	95.94	0.00e+00	853.00
IUUC-Mdo-062511	Monodelphis domestica	81.45	8.00e-91	327.00
IUUC-Mmu-064258	Mus musculus	95.10	0.00e+00	843.00
IUUC-Mpu-065911	Mustela putorius furo	96.50	0.00e+00	862.00
IUUC-Mlu-067575	Myotis lucifugus	80.16	3.00e-127	448.00
IUUC-Ont-072493	Oreochromis niloticus	65.69	2.00e-80	293.00
IUUC-Ola-086584	Oryzias latipes	61.66	4.00e-89	322.00
IUUC-Oga-088774	Otolemur garnettii	95.80	0.00e+00	902.00
IUUC-Ptr-090491	Pan troglodytes	99.59	2.00e-121	429.00
IUUC-Pma-094179	Petromyzon marinus	70.51	4.00e-31	125.00
IUUC-Pfo-096282	Poecilia formosa	59.46	3.00e-87	316.00
IUUC-Pab-098488	Pongo abelii	98.76	1.00e-177	616.00
IUUC-Pca-100667	Procavia capensis	96.89	8.00e-143	501.00
IUUC-Pva-102421	Pteropus vampyrus	96.36	0.00e+00	847.00
IUUC-Rno-105528	Rattus norvegicus	91.68	0.00e+00	805.00
IUUC-Sar-113478	Sorex araneus	98.76	3.00e-119	422.00
IUUC-Ssc-115420	Sus scrofa	93.99	0.00e+00	861.00
IUUC-Tgu-116642	Taeniopygia guttata	71.88	2.00e-106	379.00
IUUC-Tru-118583	Takifugu rubripes	60.44	5.00e-85	308.00
IUUC-Xtr-132210	Xenopus tropicalis	59.06	0.00e+00	666.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence