iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106647

Ensembl Protein ID

ENSSHAP00000015611.1

UniProt Accession

G3WJK6; G3WJK6_SARHA

Genbank Protein ID

ENSSHAP00000015611

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01164326

Gene Name

NPLOC4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000013303.1	ENSSHAT00000015739.1	ENSSHAP00000015611.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/NZF	95.25	0.00e+00	1190.00	IUUC-Hsa-046334
UBD/ZnF/NZF	95.93	0.00e+00	1196.00	IUUC-Mmu-063916
UBD/ZnF/NZF	95.59	0.00e+00	1192.00	IUUC-Rno-105582
UBD/ZnF/Other	34.59	2.00e-94	341.00	IUUC-Sce-106145

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MSGGEHDRLL RYLCQETPNE IIRVQSPEGV KRITATKRET AATFLKKVAK EFGFRNNGFS 60
VYINRNKTGE ITASPNKSLN LLKIKHGDLL FLFPSSLAGP SSDMETSSSQ ALRAWGAPNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCCTGGAT ACAAATCAAG AAACCTTGCC CAGCCCCTCT CAGTCCCACA GCTGATGACT 60
TTCTATTTGC TTTGGGCAGC TAGGAGGCAC GGCGGATGAA ACGCCAGGGT GTGAGTGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016563--Npl4
IPR007717--NPL4_C
IPR024682--Npl4_Ub-like_dom
IPR007716--NPL4_Zn-bd_put
IPR029071--Ubiquitin-rel_dom

Pfam

PF05021--NPL4
PF11543--UN_NPL4
PF05020--zf-NPL4

Gene Ontology

GO:0005634--C:nucleus
GO:0036501--C:UFD1-NPL4 complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0039536--P:negative regulation of RIG-I signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0030970--P:retrograde protein transport, ER to cytosol
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000460	Aegilops tauschii	28.04	4.00e-15	75.50
IUUC-Aml-002268	Ailuropoda melanoleuca	94.92	0.00e+00	1161.00
IUUC-Atr-002939	Amborella trichopoda	29.33	4.00e-19	88.60
IUUC-Apl-003496	Anas platyrhynchos	91.90	0.00e+00	1094.00
IUUC-Aca-005230	Anolis carolinensis	92.39	0.00e+00	1150.00
IUUC-Aly-006056	Arabidopsis lyrata	30.41	6.00e-23	101.00
IUUC-Ath-006993	Arabidopsis thaliana	28.15	3.00e-21	95.90
IUUC-Ago-007954	Ashbya gossypii	37.10	1.00e-79	290.00
IUUC-Acl-008208	Aspergillus clavatus	32.43	2.00e-89	323.00
IUUC-Afl-008574	Aspergillus flavus	36.28	7.00e-90	324.00
IUUC-Afu-008825	Aspergillus fumigatus	34.55	3.00e-95	342.00
IUUC-Ani-009495	Aspergillus nidulans	38.95	4.00e-93	335.00
IUUC-Ang-009762	Aspergillus niger	33.61	6.00e-88	318.00
IUUC-Aor-010199	Aspergillus oryzae	34.05	5.00e-88	318.00
IUUC-Ate-010592	Aspergillus terreus	37.43	2.00e-91	329.00
IUUC-Ame-011587	Astyanax mexicanus	74.60	2.00e-104	372.00
IUUC-Bgr-012124	Blumeria graminis	33.28	2.00e-89	322.00
IUUC-Bta-013312	Bos taurus	96.10	0.00e+00	1196.00
IUUC-Bci-013648	Botrytis cinerea	32.57	6.00e-94	338.00
IUUC-Bdi-014326	Brachypodium distachyon	29.20	1.00e-15	77.00
IUUC-Bol-016294	Brassica oleracea	28.74	4.00e-21	95.50
IUUC-Bra-017023	Brassica rapa	28.74	5.00e-21	95.50
IUUC-Cel-018713	Caenorhabditis elegans	43.68	4.00e-126	444.00
IUUC-Cja-018869	Callithrix jacchus	94.92	0.00e+00	1165.00
IUUC-Cfa-020757	Canis familiaris	95.76	0.00e+00	1177.00
IUUC-Cpo-022390	Cavia porcellus	95.60	0.00e+00	1165.00
IUUC-Csa-023366	Chlorocebus sabaeus	95.42	0.00e+00	1194.00
IUUC-Cho-024455	Choloepus hoffmanni	78.36	0.00e+00	833.00
IUUC-Cin-025638	Ciona intestinalis	48.64	2.00e-145	508.00
IUUC-Csv-026310	Ciona savignyi	45.93	4.00e-133	468.00
IUUC-Cgl-026685	Colletotrichum gloeosporioides	33.66	2.00e-89	322.00
IUUC-Cne-026794	Cryptococcus neoformans	30.98	6.00e-69	255.00
IUUC-Cme-027248	Cyanidioschyzon merolae	27.22	4.00e-16	79.00
IUUC-Dre-027689	Danio rerio	81.12	0.00e+00	1018.00
IUUC-Dno-030004	Dasypus novemcinctus	94.41	0.00e+00	1167.00
IUUC-Dor-030585	Dipodomys ordii	95.69	0.00e+00	972.00
IUUC-Dse-031202	Dothistroma septosporum	33.95	2.00e-89	323.00
IUUC-Dme-032092	Drosophila melanogaster	47.99	6.00e-171	593.00
IUUC-Ete-033009	Echinops telfairi	95.95	5.00e-99	354.00
IUUC-Eca-034001	Equus caballus	96.27	0.00e+00	1200.00
IUUC-Eeu-034485	Erinaceus europaeus	79.81	0.00e+00	824.00
IUUC-Fca-036128	Felis catus	95.08	0.00e+00	1132.00
IUUC-Fal-037523	Ficedula albicollis	92.89	0.00e+00	1154.00
IUUC-Fox-037802	Fusarium oxysporum	34.05	9.00e-95	340.00
IUUC-Fso-038152	Fusarium solani	33.17	1.00e-94	340.00
IUUC-Gmo-038486	Gadus morhua	75.60	0.00e+00	932.00
IUUC-Ggr-039916	Gaeumannomyces graminis	36.90	1.00e-85	310.00
IUUC-Gga-041208	Gallus gallus	93.74	0.00e+00	1169.00
IUUC-Gac-042304	Gasterosteus aculeatus	78.68	0.00e+00	962.00
IUUC-Gma-044178	Glycine max	27.60	6.00e-16	78.20
IUUC-Ggo-045236	Gorilla gorilla	91.54	0.00e+00	1136.00
IUUC-Hsa-046334	Homo sapiens	95.25	0.00e+00	1190.00
IUUC-Hvu-047323	Hordeum vulgare	26.22	3.00e-08	51.60
IUUC-Itr-047878	Ictidomys tridecemlineatus	95.93	0.00e+00	721.00
IUUC-Lch-050302	Latimeria chalumnae	84.85	0.00e+00	1053.00
IUUC-Lpe-051362	Leersia perrieri	28.57	3.00e-17	82.80
IUUC-Loc-052548	Lepisosteus oculatus	83.33	0.00e+00	998.00
IUUC-Lma-053092	Leptosphaeria maculans	34.54	1.00e-96	347.00
IUUC-Laf-053911	Loxodonta africana	95.09	0.00e+00	1182.00
IUUC-Mcc-055830	Macaca mulatta	95.26	0.00e+00	1196.00
IUUC-Meu-056460	Macropus eugenii	61.19	3.00e-155	541.00
IUUC-Mor-057189	Magnaporthe oryzae	36.49	4.00e-88	318.00
IUUC-Mpo-057366	Magnaporthe poae	37.97	1.00e-85	310.00
IUUC-Mtr-057834	Medicago truncatula	27.35	9.00e-18	84.30
IUUC-Mla-059190	Melampsora laricipopulina	36.97	1.00e-81	297.00
IUUC-Mga-060036	Meleagris gallopavo	93.41	0.00e+00	1168.00
IUUC-Mvi-060275	Microbotryum violaceum	34.87	2.00e-79	290.00
IUUC-Mmr-061300	Microcebus murinus	95.26	0.00e+00	1190.00
IUUC-Mdo-062911	Monodelphis domestica	99.23	0.00e+00	1078.00
IUUC-Mmu-063916	Mus musculus	95.93	0.00e+00	1172.00
IUUC-Mac-065601	Musa acuminata	27.57	7.00e-12	64.70
IUUC-Mpu-065912	Mustela putorius furo	94.92	0.00e+00	1165.00
IUUC-Mlu-067965	Myotis lucifugus	94.07	0.00e+00	1151.00
IUUC-Nfi-068465	Neosartorya fischeri	34.71	1.00e-95	343.00
IUUC-Ncr-068936	Neurospora crassa	33.39	2.00e-91	330.00
IUUC-Nle-069570	Nomascus leucogenys	95.08	0.00e+00	1185.00
IUUC-Opr-071097	Ochotona princeps	90.35	0.00e+00	913.00
IUUC-Ont-071430	Oreochromis niloticus	80.33	0.00e+00	1006.00
IUUC-Oan-073709	Ornithorhynchus anatinus	83.92	0.00e+00	806.00
IUUC-Ocu-074875	Oryctolagus cuniculus	89.88	0.00e+00	1105.00
IUUC-Oba-075214	Oryza barthii	27.34	2.00e-17	83.20
IUUC-Obr-076758	Oryza brachyantha	28.41	4.00e-17	82.00
IUUC-Ogl-077665	Oryza glaberrima	27.34	2.00e-17	83.20
IUUC-Ogu-078899	Oryza glumaepatula	27.34	2.00e-17	83.20
IUUC-Oin-079167	Oryza indica	27.34	2.00e-17	83.20
IUUC-Olo-080451	Oryza longistaminata	27.84	2.00e-17	83.20
IUUC-Ome-081836	Oryza meridionalis	27.70	2.00e-17	83.20
IUUC-Oni-083019	Oryza nivara	27.34	2.00e-17	83.20
IUUC-Opu-083122	Oryza punctata	27.90	1.00e-17	84.00
IUUC-Oru-084900	Oryza rufipogon	27.34	2.00e-17	83.20
IUUC-Osa-086054	Oryza sativa	27.34	2.00e-17	83.20
IUUC-Ola-087077	Oryzias latipes	69.84	0.00e+00	832.00
IUUC-Olu-087601	Ostreococcus lucimarinus	25.95	5.00e-06	45.40
IUUC-Oga-088049	Otolemur garnettii	81.28	0.00e+00	994.00
IUUC-Oar-089678	Ovis aries	96.44	0.00e+00	1199.00
IUUC-Ptr-091380	Pan troglodytes	94.52	0.00e+00	1117.00
IUUC-Pan-092821	Papio anubis	94.24	0.00e+00	1179.00
IUUC-Psi-093074	Pelodiscus sinensis	94.09	0.00e+00	1161.00
IUUC-Pma-094102	Petromyzon marinus	69.02	0.00e+00	881.00
IUUC-Pno-094987	Phaeosphaeria nodorum	34.92	1.00e-94	341.00
IUUC-Ppa-095368	Physcomitrella patens	27.93	6.00e-18	84.70
IUUC-Pfo-097245	Poecilia formosa	82.18	0.00e+00	978.00
IUUC-Pab-098763	Pongo abelii	95.43	0.00e+00	1195.00
IUUC-Pop-099355	Populus trichocarpa	30.77	6.00e-15	74.70
IUUC-Ppe-101990	Prunus persica	28.80	2.00e-18	86.30
IUUC-Pva-102308	Pteropus vampyrus	87.05	0.00e+00	949.00
IUUC-Pgr-103553	Puccinia graminis	32.61	1.00e-78	287.00
IUUC-Pte-104100	Pyrenophora teres	33.28	8.00e-92	331.00
IUUC-Pyt-104482	Pyrenophora triticirepentis	33.61	6.00e-91	328.00
IUUC-Rno-105582	Rattus norvegicus	95.59	0.00e+00	1169.00
IUUC-Sce-106145	Saccharomyces cerevisiae	34.59	3.00e-91	329.00
IUUC-Sja-107972	Schizosaccharomyces japonicus	35.97	5.00e-87	315.00
IUUC-Spo-108281	Schizosaccharomyces pombe	35.19	5.00e-93	334.00
IUUC-Ssl-108617	Sclerotinia sclerotiorum	36.64	1.00e-90	327.00
IUUC-Smo-108933	Selaginella moellendorffii	30.40	1.00e-18	87.80
IUUC-Sit-110083	Setaria italica	29.18	2.00e-16	80.10
IUUC-Sly-111645	Solanum lycopersicum	27.12	9.00e-17	81.30
IUUC-Stu-112422	Solanum tuberosum	27.12	5.00e-17	82.00
IUUC-Sbi-113987	Sorghum bicolor	30.43	4.00e-17	82.00
IUUC-Sre-115095	Sporisorium reilianum	33.89	3.00e-81	296.00
IUUC-Ssc-116141	Sus scrofa	94.30	0.00e+00	1061.00
IUUC-Tgu-117492	Taeniopygia guttata	93.08	0.00e+00	877.00
IUUC-Tru-118463	Takifugu rubripes	77.94	0.00e+00	951.00
IUUC-Tsy-118993	Tarsius syrichta	86.76	0.00e+00	988.00
IUUC-Tni-119896	Tetraodon nigroviridis	80.34	0.00e+00	960.00
IUUC-Tca-121169	Theobroma cacao	28.43	1.00e-19	90.50
IUUC-Tre-122046	Trichoderma reesei	32.95	1.00e-90	327.00
IUUC-Tvi-122415	Trichoderma virens	33.28	3.00e-91	329.00
IUUC-Tae-125503	Triticum aestivum	28.04	4.00e-15	75.50
IUUC-Tur-126703	Triticum urartu	39.39	1.30e-01	30.00
IUUC-Tme-127123	Tuber melanosporum	35.84	3.00e-101	362.00
IUUC-Tbe-127629	Tupaia belangeri	89.74	3.00e-153	535.00
IUUC-Ttr-128476	Tursiops truncatus	85.33	0.00e+00	959.00
IUUC-Uma-129492	Ustilago maydis	34.27	5.00e-83	302.00
IUUC-Vda-129702	Verticillium dahliae	33.98	4.00e-89	322.00
IUUC-Vvi-131090	Vitis vinifera	30.41	3.00e-14	72.80
IUUC-Xtr-131786	Xenopus tropicalis	86.87	0.00e+00	1054.00
IUUC-Xma-133997	Xiphophorus maculatus	78.57	0.00e+00	971.00
IUUC-Yli-134537	Yarrowia lipolytica	35.17	7.00e-89	321.00
IUUC-Zma-134847	Zea mays	29.72	3.00e-18	85.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence