iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033873

Ensembl Protein ID

ENSECAP00000009231.1

UniProt Accession

F7ALM2; F7ALM2_HORSE

Protein Name

Uncharacterized protein

Gene Name

HGS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000010874.1	ENSECAT00000011767.1	ENSECAP00000009231.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/VHS	6.10e-51	172.0	4	132

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/VHS

   S: 1    atselvtsedwelileicdliqetkegakdalralrkrinnknphvalraLtlLdscvsnCgkkfhvevaskdlleelrellknenepk 89
           ats+l+ ++dwe+il+icdli++ +++ak+a+ +++k++n+knphval+aL++++s+v+nCg+++h+eva+k+++eel+ellk+++e++
   Q: 4    ATSQLLLETDWESILQICDLIRQGDTQAKYAVSSIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKELLKRQVEVN 92
           799************************************************************************************** PP
   S: 90   vieKlkalivsWadelknepalslivaliktlkeeGlefp 129
           v++K+++li++Wa++++nep++++++++++ +k eG++fp
   Q: 93   VRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFP 132
           ***************************************8 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

LDKATSQLLL ETDWESILQI CDLIRQGDTQ AKYAVSSIKK KVNDKNPHVA LYALEVMESV 60
VKNCGQTVHD EVANKQTMEE LKELLKRQVE VNVRNKILYL IQAWAHAFRN EPKYKVVQDT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAGACAAAG CAACCAGCCA GCTTCTGCTG GAGACCGACT GGGAGTCCAT CCTCCAGATT 60
TGCGACCTGA TCCGCCAGGG GGACACACAG TAAGTGGGGA GGGCCTGTGC TCACTAGAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008942--ENTH_VHS
IPR024641--HRS_helical
IPR017073--Ubi-bd_Hrs_VPS27
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF12210--Hrs_helical
PF00790--VHS

SMART

SM00064--FYVE
SM00288--VHS

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0005764--C:lysosome
GO:0046872--F:metal ion binding
GO:0010324--P:membrane invagination
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:1903543--P:positive regulation of exosomal secretion
GO:0010628--P:positive regulation of gene expression
GO:0072657--P:protein localization to membrane
GO:0006622--P:protein targeting to lysosome
GO:0043405--P:regulation of MAP kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001518	Ailuropoda melanoleuca	90.69	0.00e+00	1040.00
IUUC-Apl-003662	Anas platyrhynchos	85.12	0.00e+00	994.00
IUUC-Aca-004940	Anolis carolinensis	84.66	0.00e+00	1169.00
IUUC-Ago-007931	Ashbya gossypii	30.33	6.00e-27	115.00
IUUC-Acl-008274	Aspergillus clavatus	30.88	8.00e-40	158.00
IUUC-Afl-008521	Aspergillus flavus	33.57	3.00e-41	163.00
IUUC-Afu-008774	Aspergillus fumigatus	32.59	4.00e-41	162.00
IUUC-Ani-009445	Aspergillus nidulans	32.96	8.00e-42	165.00
IUUC-Ang-009863	Aspergillus niger	33.33	4.00e-42	166.00
IUUC-Ate-010444	Aspergillus terreus	34.12	6.00e-43	168.00
IUUC-Ame-011111	Astyanax mexicanus	77.42	0.00e+00	917.00
IUUC-Bgr-012087	Blumeria graminis	31.72	1.00e-43	171.00
IUUC-Bta-012506	Bos taurus	94.79	0.00e+00	1192.00
IUUC-Bci-013782	Botrytis cinerea	31.45	1.00e-42	167.00
IUUC-Cel-018493	Caenorhabditis elegans	52.66	1.00e-66	247.00
IUUC-Cja-019998	Callithrix jacchus	89.86	0.00e+00	1075.00
IUUC-Cfa-020615	Canis familiaris	91.71	0.00e+00	1097.00
IUUC-Cpo-022019	Cavia porcellus	92.05	0.00e+00	1209.00
IUUC-Csa-023596	Chlorocebus sabaeus	93.62	0.00e+00	1090.00
IUUC-Cin-025488	Ciona intestinalis	46.70	2.00e-124	439.00
IUUC-Csv-025802	Ciona savignyi	49.64	4.00e-114	404.00
IUUC-Cgl-026560	Colletotrichum gloeosporioides	35.90	4.00e-41	162.00
IUUC-Cne-026847	Cryptococcus neoformans	31.32	1.00e-36	147.00
IUUC-Dre-028353	Danio rerio	77.95	0.00e+00	905.00
IUUC-Dno-029005	Dasypus novemcinctus	87.89	0.00e+00	1128.00
IUUC-Dor-030280	Dipodomys ordii	90.96	0.00e+00	1142.00
IUUC-Dse-031238	Dothistroma septosporum	38.71	3.00e-43	170.00
IUUC-Dme-031952	Drosophila melanogaster	48.66	4.00e-79	289.00
IUUC-Ete-032235	Echinops telfairi	97.61	5.00e-127	448.00
IUUC-Eeu-034652	Erinaceus europaeus	97.60	2.00e-99	356.00
IUUC-Fca-036563	Felis catus	94.54	0.00e+00	1157.00
IUUC-Fal-036649	Ficedula albicollis	84.45	0.00e+00	1061.00
IUUC-Fox-037962	Fusarium oxysporum	32.86	2.00e-40	160.00
IUUC-Fso-038396	Fusarium solani	33.57	7.00e-41	162.00
IUUC-Gmo-039510	Gadus morhua	74.36	0.00e+00	931.00
IUUC-Ggr-039938	Gaeumannomyces graminis	32.78	6.00e-39	155.00
IUUC-Gga-040201	Gallus gallus	83.25	0.00e+00	1104.00
IUUC-Gac-041459	Gasterosteus aculeatus	76.49	0.00e+00	937.00
IUUC-Ggo-044573	Gorilla gorilla	93.75	0.00e+00	1177.00
IUUC-Hsa-046009	Homo sapiens	93.88	0.00e+00	1221.00
IUUC-Itr-049065	Ictidomys tridecemlineatus	93.75	0.00e+00	1236.00
IUUC-Kpa-049327	Komagataella pastoris	31.48	3.00e-32	133.00
IUUC-Lch-049944	Latimeria chalumnae	77.93	7.00e-161	560.00
IUUC-Loc-051850	Lepisosteus oculatus	79.15	0.00e+00	1010.00
IUUC-Lma-053252	Leptosphaeria maculans	35.62	2.00e-41	164.00
IUUC-Laf-053346	Loxodonta africana	83.94	0.00e+00	1018.00
IUUC-Mcc-055789	Macaca mulatta	93.56	0.00e+00	1154.00
IUUC-Meu-056329	Macropus eugenii	74.07	8.00e-167	580.00
IUUC-Mor-057205	Magnaporthe oryzae	34.28	4.00e-39	156.00
IUUC-Mpo-057295	Magnaporthe poae	33.44	4.00e-40	159.00
IUUC-Mla-058849	Melampsora laricipopulina	33.82	8.00e-32	132.00
IUUC-Mga-059361	Meleagris gallopavo	82.86	0.00e+00	1058.00
IUUC-Mvi-060561	Microbotryum violaceum	32.54	3.00e-38	153.00
IUUC-Mmr-061122	Microcebus murinus	93.35	0.00e+00	995.00
IUUC-Mdo-062171	Monodelphis domestica	90.55	0.00e+00	1185.00
IUUC-Mmu-063952	Mus musculus	92.58	0.00e+00	1259.00
IUUC-Mpu-065852	Mustela putorius furo	93.38	0.00e+00	1119.00
IUUC-Mlu-066996	Myotis lucifugus	86.29	9.00e-154	536.00
IUUC-Nfi-068539	Neosartorya fischeri	32.59	2.00e-41	164.00
IUUC-Ncr-068726	Neurospora crassa	39.91	4.00e-40	159.00
IUUC-Nle-070148	Nomascus leucogenys	88.18	0.00e+00	1051.00
IUUC-Opr-070833	Ochotona princeps	73.50	0.00e+00	805.00
IUUC-Ont-071261	Oreochromis niloticus	77.67	0.00e+00	945.00
IUUC-Oan-073684	Ornithorhynchus anatinus	71.23	2.00e-154	538.00
IUUC-Ola-087570	Oryzias latipes	75.50	0.00e+00	954.00
IUUC-Oga-089087	Otolemur garnettii	91.25	0.00e+00	1075.00
IUUC-Oar-089534	Ovis aries	94.66	0.00e+00	1192.00
IUUC-Ptr-091654	Pan troglodytes	88.28	0.00e+00	1065.00
IUUC-Pan-092652	Papio anubis	93.75	0.00e+00	1160.00
IUUC-Pno-095125	Phaeosphaeria nodorum	38.64	4.00e-42	166.00
IUUC-Pfo-096757	Poecilia formosa	76.34	0.00e+00	918.00
IUUC-Pab-097788	Pongo abelii	94.52	0.00e+00	817.00
IUUC-Pca-100145	Procavia capensis	78.52	0.00e+00	887.00
IUUC-Pva-102965	Pteropus vampyrus	90.16	0.00e+00	1137.00
IUUC-Pgr-103609	Puccinia graminis	34.69	6.00e-34	138.00
IUUC-Ptt-103865	Puccinia triticina	35.71	9.00e-35	142.00
IUUC-Pte-104095	Pyrenophora teres	35.62	5.00e-41	162.00
IUUC-Pyt-104668	Pyrenophora triticirepentis	33.09	4.00e-41	163.00
IUUC-Rno-105125	Rattus norvegicus	92.62	0.00e+00	1165.00
IUUC-Sce-106192	Saccharomyces cerevisiae	28.05	3.00e-26	113.00
IUUC-Sha-107066	Sarcophilus harrisii	91.03	0.00e+00	1152.00
IUUC-Sja-107931	Schizosaccharomyces japonicus	32.13	6.00e-41	162.00
IUUC-Spo-108220	Schizosaccharomyces pombe	33.47	4.00e-37	149.00
IUUC-Stu-112464	Solanum tuberosum	45.90	1.00e-13	72.40
IUUC-Sar-113393	Sorex araneus	92.63	1.00e-107	384.00
IUUC-Sre-114986	Sporisorium reilianum	38.60	8.00e-42	165.00
IUUC-Tgu-117505	Taeniopygia guttata	82.88	0.00e+00	1055.00
IUUC-Tru-118494	Takifugu rubripes	77.39	0.00e+00	981.00
IUUC-Tsy-119626	Tarsius syrichta	97.80	1.00e-48	187.00
IUUC-Tni-120174	Tetraodon nigroviridis	73.10	0.00e+00	971.00
IUUC-Tre-122191	Trichoderma reesei	33.82	6.00e-41	162.00
IUUC-Tvi-122318	Trichoderma virens	33.33	8.00e-42	165.00
IUUC-Tme-126914	Tuber melanosporum	35.64	1.00e-44	174.00
IUUC-Ttr-129095	Tursiops truncatus	94.93	0.00e+00	1230.00
IUUC-Uma-129475	Ustilago maydis	37.04	1.00e-38	155.00
IUUC-Vda-129908	Verticillium dahliae	33.21	4.00e-36	146.00
IUUC-Xtr-131900	Xenopus tropicalis	77.34	0.00e+00	1033.00
IUUC-Xma-133124	Xiphophorus maculatus	76.58	0.00e+00	959.00
IUUC-Yli-134682	Yarrowia lipolytica	36.21	2.00e-33	136.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence