iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csv-026029

Ensembl Protein ID

ENSCSAVP00000016773.1

UniProt Accession

H2ZGQ7; H2ZGQ7_CIOSA

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000009867.1	ENSCSAVT00000016955.1	ENSCSAVP00000016773.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.00e-14	52.3	93	148

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
             +lydy+a + d+L++kkG++++++  ++++++W+++ +  ++  G +P+n+v+ ++
   Q: 93   YVALYDYDARTADDLSFKKGEQLFIL--NSTEGDWWEARSLITQDTGYIPSNYVAPAN 148
           579***********************..8999**********************9876 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

MGCCTSKEKD NGGVTSVDGG THYARDPGIN SNPVVISGPQ MSSGPVSDSS RNTNQFGGFN 60
PGQMPLFNQT QSGMVPIKGM PSRPSMTGQA VRYVALYDYD ARTADDLSFK KGEQLFILNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGATAATCTT GTGAAATTAA TATATATACT GGTTCTTAAA CACTGCCTTT CTGGTAACTG 60
TACTGGTGTA CAAGTTTTGC AGTTTTTTCT GTACAGGTAA GAAGGGGTGT TATCATTCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001713	Ailuropoda melanoleuca	65.24	0.00e+00	645.00
IUUC-Apl-004032	Anas platyrhynchos	67.86	0.00e+00	657.00
IUUC-Aca-004255	Anolis carolinensis	64.67	0.00e+00	659.00
IUUC-Ame-010954	Astyanax mexicanus	63.45	0.00e+00	652.00
IUUC-Bta-012982	Bos taurus	66.60	0.00e+00	650.00
IUUC-Cel-018682	Caenorhabditis elegans	55.48	8.00e-135	472.00
IUUC-Cja-019694	Callithrix jacchus	72.90	0.00e+00	649.00
IUUC-Cfa-020060	Canis familiaris	66.05	0.00e+00	652.00
IUUC-Cpo-021557	Cavia porcellus	64.13	0.00e+00	657.00
IUUC-Csa-023713	Chlorocebus sabaeus	72.20	0.00e+00	642.00
IUUC-Cho-025014	Choloepus hoffmanni	71.53	0.00e+00	628.00
IUUC-Cin-025390	Ciona intestinalis	95.65	0.00e+00	835.00
IUUC-Dre-028491	Danio rerio	68.58	0.00e+00	635.00
IUUC-Dno-029651	Dasypus novemcinctus	66.81	0.00e+00	632.00
IUUC-Dor-030202	Dipodomys ordii	74.11	0.00e+00	649.00
IUUC-Dme-031976	Drosophila melanogaster	59.78	2.00e-152	530.00
IUUC-Ete-033170	Echinops telfairi	70.49	2.00e-179	620.00
IUUC-Eca-033970	Equus caballus	72.92	0.00e+00	645.00
IUUC-Eeu-035004	Erinaceus europaeus	54.52	1.00e-111	394.00
IUUC-Fca-036113	Felis catus	66.05	0.00e+00	652.00
IUUC-Fal-037461	Ficedula albicollis	63.74	0.00e+00	662.00
IUUC-Gmo-038929	Gadus morhua	73.27	0.00e+00	629.00
IUUC-Gga-041107	Gallus gallus	67.86	0.00e+00	657.00
IUUC-Gac-042332	Gasterosteus aculeatus	68.06	0.00e+00	652.00
IUUC-Ggo-044469	Gorilla gorilla	61.06	0.00e+00	629.00
IUUC-Hsa-047010	Homo sapiens	63.62	0.00e+00	645.00
IUUC-Itr-049014	Ictidomys tridecemlineatus	68.87	0.00e+00	644.00
IUUC-Lch-050239	Latimeria chalumnae	64.58	0.00e+00	665.00
IUUC-Loc-052812	Lepisosteus oculatus	62.91	0.00e+00	635.00
IUUC-Laf-053517	Loxodonta africana	72.43	0.00e+00	645.00
IUUC-Mcc-055626	Macaca mulatta	72.20	0.00e+00	643.00
IUUC-Meu-056155	Macropus eugenii	66.59	2.00e-167	580.00
IUUC-Mga-059310	Meleagris gallopavo	67.86	0.00e+00	657.00
IUUC-Mmr-061652	Microcebus murinus	64.72	0.00e+00	650.00
IUUC-Mdo-062963	Monodelphis domestica	63.79	0.00e+00	646.00
IUUC-Mmu-064128	Mus musculus	62.08	0.00e+00	645.00
IUUC-Mpu-066411	Mustela putorius furo	66.05	0.00e+00	652.00
IUUC-Mlu-067035	Myotis lucifugus	63.81	0.00e+00	644.00
IUUC-Nle-068978	Nomascus leucogenys	60.34	2.00e-179	620.00
IUUC-Opr-070299	Ochotona princeps	65.19	5.00e-163	565.00
IUUC-Ont-072127	Oreochromis niloticus	73.63	0.00e+00	648.00
IUUC-Oan-072997	Ornithorhynchus anatinus	72.03	0.00e+00	640.00
IUUC-Ocu-074171	Oryctolagus cuniculus	72.20	0.00e+00	644.00
IUUC-Ola-086619	Oryzias latipes	63.40	0.00e+00	656.00
IUUC-Oga-087957	Otolemur garnettii	72.90	0.00e+00	649.00
IUUC-Oar-090279	Ovis aries	66.60	0.00e+00	649.00
IUUC-Ptr-091352	Pan troglodytes	63.62	0.00e+00	644.00
IUUC-Pan-091862	Papio anubis	66.05	0.00e+00	649.00
IUUC-Psi-093310	Pelodiscus sinensis	64.75	0.00e+00	666.00
IUUC-Pma-094232	Petromyzon marinus	71.95	0.00e+00	652.00
IUUC-Pfo-096137	Poecilia formosa	68.39	0.00e+00	650.00
IUUC-Pab-098301	Pongo abelii	72.03	0.00e+00	641.00
IUUC-Pca-100245	Procavia capensis	71.53	0.00e+00	628.00
IUUC-Ppe-102072	Prunus persica	33.67	1.00e-22	100.00
IUUC-Pva-102645	Pteropus vampyrus	71.53	0.00e+00	629.00
IUUC-Rno-105544	Rattus norvegicus	72.03	0.00e+00	641.00
IUUC-Sha-107539	Sarcophilus harrisii	67.38	0.00e+00	651.00
IUUC-Sly-111528	Solanum lycopersicum	32.42	5.00e-22	98.20
IUUC-Stu-112831	Solanum tuberosum	32.32	2.00e-21	95.90
IUUC-Sar-113364	Sorex araneus	69.16	1.00e-174	604.00
IUUC-Ssc-115762	Sus scrofa	65.03	0.00e+00	644.00
IUUC-Tgu-117380	Taeniopygia guttata	63.74	0.00e+00	662.00
IUUC-Tru-117784	Takifugu rubripes	63.81	0.00e+00	659.00
IUUC-Tsy-119440	Tarsius syrichta	59.48	2.00e-143	500.00
IUUC-Tni-120843	Tetraodon nigroviridis	69.28	0.00e+00	636.00
IUUC-Tca-121389	Theobroma cacao	31.77	6.00e-20	91.30
IUUC-Tbe-127707	Tupaia belangeri	71.53	0.00e+00	627.00
IUUC-Ttr-128893	Tursiops truncatus	62.62	0.00e+00	645.00
IUUC-Vpa-130060	Vicugna pacos	72.20	0.00e+00	642.00
IUUC-Xtr-132322	Xenopus tropicalis	64.55	0.00e+00	658.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence