iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012827

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02056451

Gene Name

RNF125

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000003113.4	ENSBTAT00000004048.4	ENSBTAP00000004048.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	3.10e-10	40.1	33	99
E3 activity/RING/RING	3.10e-08	34.1	37	76

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawce 70
             f C++ le+ ++Pv + +G+++ rs+I+  l++++ tcP +r+ l +e +    + +r+ +++++
   Q: 33   TSFDCSVCLEVLHHPVRTRCGHVFCRSCIATSLKNNKWTCPYCRAYLPSEGVPAADVAKRMKSEFRN 99
           579******************************99999************99999999999999975 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C++Cle + + p+ ++CgHvf+++C+   +      ++++++CP+Cr
   Q: 37   CSVCLEVLHH-PVRTRCGHVFCRSCIaTSL------KNNKWTCPYCR 76
           ********99.777***********95555......**********8 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MGSVLSSDSG KSAPASATPR ALERRGDPEL PVTSFDCSVC LEVLHHPVRT RCGHVFCRSC 60
IATSLKNNKW TCPYCRAYLP SEGVPAADVA KRMKSEFRNC TECDTLVCLS EMRAHTRTCQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTCCG TGCTGAGCAG CGATAGCGGG AAATCCGCGC CCGCCTCGGC CACCCCGCGG 60
GCCTTGGAGC GCCGGGGGGA CCCCGAGCTG CCCGTCACGT CTTTCGACTG TTCTGTGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR008598--Di19_Zn_binding_dom
IPR034734--ZF_C2HC_RNF
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51803--ZF_C2HC_RNF
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF05605--zf-Di19

SMART

SM00184--RING

Gene Ontology

GO:0000139--C:Golgi membrane
GO:0005622--C:intracellular
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0039536--P:negative regulation of RIG-I signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

bta:519541

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001992	Ailuropoda melanoleuca	90.95	2.00e-126	444.00
IUUC-Aca-004839	Anolis carolinensis	61.45	1.00e-65	242.00
IUUC-Cja-018794	Callithrix jacchus	90.95	7.00e-126	442.00
IUUC-Cfa-021234	Canis familiaris	89.22	2.00e-115	407.00
IUUC-Cpo-022412	Cavia porcellus	77.59	1.00e-102	365.00
IUUC-Csa-023406	Chlorocebus sabaeus	90.48	3.00e-125	440.00
IUUC-Cho-024427	Choloepus hoffmanni	73.45	7.00e-73	266.00
IUUC-Dno-030085	Dasypus novemcinctus	89.22	2.00e-124	437.00
IUUC-Dor-030911	Dipodomys ordii	69.83	5.00e-76	276.00
IUUC-Ete-032469	Echinops telfairi	84.05	4.00e-117	413.00
IUUC-Eca-034352	Equus caballus	91.38	2.00e-126	444.00
IUUC-Eeu-034889	Erinaceus europaeus	76.62	3.00e-100	357.00
IUUC-Fca-036116	Felis catus	89.66	2.00e-117	414.00
IUUC-Hsa-046518	Homo sapiens	90.04	5.00e-124	436.00
IUUC-Itr-048344	Ictidomys tridecemlineatus	92.66	1.00e-97	348.00
IUUC-Laf-053363	Loxodonta africana	90.60	4.00e-126	443.00
IUUC-Meu-056101	Macropus eugenii	76.78	1.00e-94	338.00
IUUC-Mdo-062046	Monodelphis domestica	72.10	5.00e-97	346.00
IUUC-Mmu-063184	Mus musculus	81.43	3.00e-56	209.00
IUUC-Mpu-065708	Mustela putorius furo	89.66	1.00e-124	438.00
IUUC-Mlu-067561	Myotis lucifugus	87.57	4.00e-92	330.00
IUUC-Nle-069665	Nomascus leucogenys	89.72	3.00e-114	403.00
IUUC-Opr-070301	Ochotona princeps	78.02	6.00e-105	373.00
IUUC-Ocu-074562	Oryctolagus cuniculus	90.48	1.00e-65	240.00
IUUC-Oga-088958	Otolemur garnettii	91.81	4.00e-127	446.00
IUUC-Oar-089541	Ovis aries	97.74	7.00e-102	362.00
IUUC-Ptr-090989	Pan troglodytes	90.48	5.00e-125	439.00
IUUC-Pan-092372	Papio anubis	89.61	3.00e-124	437.00
IUUC-Pab-098718	Pongo abelii	77.92	3.00e-101	360.00
IUUC-Pca-100453	Procavia capensis	89.22	2.00e-123	434.00
IUUC-Pva-102931	Pteropus vampyrus	90.09	2.00e-116	411.00
IUUC-Rno-105771	Rattus norvegicus	86.32	3.00e-99	354.00
IUUC-Sha-107557	Sarcophilus harrisii	71.98	1.00e-102	365.00
IUUC-Sja-107981	Schizosaccharomyces japonicus	43.08	5.00e-08	51.60
IUUC-Spo-108312	Schizosaccharomyces pombe	43.08	3.00e-08	52.80
IUUC-Sar-113435	Sorex araneus	89.68	1.00e-65	241.00
IUUC-Ssc-116388	Sus scrofa	92.67	4.00e-129	453.00
IUUC-Tsy-119439	Tarsius syrichta	92.09	6.00e-97	345.00
IUUC-Tbe-127417	Tupaia belangeri	68.14	1.00e-71	262.00
IUUC-Ttr-129212	Tursiops truncatus	94.83	7.00e-131	459.00
IUUC-Vpa-130153	Vicugna pacos	91.81	3.00e-127	447.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence