iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020203

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03012675

Gene Name

CDC34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000029464.1	ENSCAFT00000045306.1	ENSCAFP00000039112.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.90e-48	162.7	15	153

Active Site

Position(s)	Description	Evidence
93	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk..... 87
            elk l+++p+eg+++++vde dl++wev+i+Gp++t+Yegg+Fk++++fp dYP++PP ++fltk++hPn+ye+G+vC+sil+     
   Q: 15   LELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHppvdd 103
           599********************************************************************************999999 PP
   S: 88   ......eeekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
                 ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ +++k++e
   Q: 104  pqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKE 153
           999*9******************************************998 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MARPLVPSSQ KALLLELKGL QEEPVEGFRV TLVDEGDLYN WEVAIFGPPN TYYEGGYFKA 60
RLKFPIDYPY SPPAFRFLTK MWHPNIYETG DVCISILHPP VDDPQSGELP SERWNPTQNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCCGGC CGCTGGTGCC CAGCTCGCAG AAGGCGCTGC TGCTGGAGCT CAAGGGGCTG 60
CAGGAGGAGC CGGTGGAGGG CTTCCGGGTG ACCCTGGTGG ACGAGGGCGA CCTGTACAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0016607--C:nuclear speck
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0035458--P:cellular response to interferon-beta
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination

KEGG

cfa:476759

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001600	Ailuropoda melanoleuca	99.55	2.00e-131	461.00
IUUC-Ame-011425	Astyanax mexicanus	89.55	1.00e-108	385.00
IUUC-Bta-012516	Bos taurus	99.51	2.00e-120	424.00
IUUC-Cja-018852	Callithrix jacchus	90.35	3.00e-104	370.00
IUUC-Cpo-022139	Cavia porcellus	91.23	1.00e-120	425.00
IUUC-Csa-023371	Chlorocebus sabaeus	98.66	7.00e-123	432.00
IUUC-Dre-028367	Danio rerio	89.05	3.00e-108	384.00
IUUC-Dor-030875	Dipodomys ordii	99.11	2.00e-123	434.00
IUUC-Fca-035832	Felis catus	98.80	1.00e-95	341.00
IUUC-Gmo-039414	Gadus morhua	90.05	2.00e-109	387.00
IUUC-Gga-040694	Gallus gallus	96.19	8.00e-124	435.00
IUUC-Gac-042485	Gasterosteus aculeatus	88.56	3.00e-109	387.00
IUUC-Ggo-044806	Gorilla gorilla	99.11	5.00e-123	433.00
IUUC-Hsa-046245	Homo sapiens	99.11	7.00e-123	432.00
IUUC-Lch-049845	Latimeria chalumnae	90.05	2.00e-109	388.00
IUUC-Loc-052932	Lepisosteus oculatus	91.54	3.00e-111	394.00
IUUC-Mcc-054665	Macaca mulatta	95.09	9.00e-116	409.00
IUUC-Mga-060075	Meleagris gallopavo	95.76	1.00e-123	435.00
IUUC-Mmr-061165	Microcebus murinus	95.54	1.00e-121	428.00
IUUC-Mdo-061825	Monodelphis domestica	97.77	2.00e-120	424.00
IUUC-Mmu-064168	Mus musculus	100.00	9.00e-121	425.00
IUUC-Mpu-066009	Mustela putorius furo	99.55	3.00e-131	460.00
IUUC-Opr-070826	Ochotona princeps	93.49	1.00e-109	388.00
IUUC-Ont-071745	Oreochromis niloticus	90.15	1.00e-110	392.00
IUUC-Oan-073287	Ornithorhynchus anatinus	91.10	5.00e-119	419.00
IUUC-Ocu-074902	Oryctolagus cuniculus	95.63	1.00e-116	411.00
IUUC-Oga-088845	Otolemur garnettii	97.32	9.00e-127	445.00
IUUC-Ptr-090916	Pan troglodytes	94.20	9.00e-118	415.00
IUUC-Pan-092577	Papio anubis	98.66	7.00e-123	432.00
IUUC-Psi-093039	Pelodiscus sinensis	94.38	4.00e-89	320.00
IUUC-Pfo-096435	Poecilia formosa	89.55	1.00e-109	389.00
IUUC-Pab-098200	Pongo abelii	99.02	1.00e-111	395.00
IUUC-Pca-100169	Procavia capensis	86.43	6.00e-66	243.00
IUUC-Pva-102875	Pteropus vampyrus	100.00	1.00e-85	308.00
IUUC-Rno-106079	Rattus norvegicus	100.00	9.00e-121	425.00
IUUC-Ssc-115699	Sus scrofa	89.84	2.00e-88	317.00
IUUC-Tgu-117466	Taeniopygia guttata	94.07	9.00e-122	429.00
IUUC-Tni-120864	Tetraodon nigroviridis	86.07	2.00e-105	374.00
IUUC-Xtr-132285	Xenopus tropicalis	89.50	8.00e-118	416.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence