iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092577

Ensembl Protein ID

ENSPANP00000002342.1

UniProt Accession

A0A0A0MUN1; A0A0A0MUN1_PAPAN

Genbank Protein ID

ENSPANP00000002342

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01043215

Gene Name

CDC34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000006500.1	ENSPANT00000017418.1	ENSPANP00000002342.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.20e-48	162.7	15	153

Active Site

Position(s)	Description	Evidence
93	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk..... 87
            elk l+++p+eg+++++vde dl++wev+i+Gp++t+Yegg+Fk++++fp dYP++PP ++fltk++hPn+ye+G+vC+sil+     
   Q: 15   LELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHppvdd 103
           599********************************************************************************999999 PP
   S: 88   ......eeekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
                 ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ +++k++e
   Q: 104  pqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKE 153
           999*9******************************************998 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MARPLVPSSQ KALLLELKGL QEEPVEGFRV TLVDEGDLYN WEVAIFGPPN TYYEGGYFKA 60
RLKFPIDYPY SPPAFRFLTK MWHPNIYETG DVCISILHPP VDDPQSGELP SERWNPTQNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGCGGCGC CGACCCCGGG GCCCTCCGCC GCCGCCATGG CCCGGCCGCT AGTGCCCAGC 60
TCGCAGAAGG CGCTGCTGCT GGAGCTCAAG GGGCTGCAGG AAGAGCCGGT CGAGGGCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005829--C:cytosol
GO:0016607--C:nuclear speck
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0035458--P:cellular response to interferon-beta
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001600	Ailuropoda melanoleuca	98.66	9.00e-130	455.00
IUUC-Ate-010563	Aspergillus terreus	43.72	1.00e-36	146.00
IUUC-Ame-011425	Astyanax mexicanus	89.55	1.00e-108	385.00
IUUC-Bta-012516	Bos taurus	99.51	3.00e-120	424.00
IUUC-Cja-018852	Callithrix jacchus	89.47	6.00e-104	369.00
IUUC-Cfa-020203	Canis familiaris	98.66	4.00e-121	426.00
IUUC-Cpo-022139	Cavia porcellus	91.23	1.00e-120	424.00
IUUC-Csa-023371	Chlorocebus sabaeus	100.00	2.00e-122	431.00
IUUC-Dre-028367	Danio rerio	89.05	3.00e-108	384.00
IUUC-Dor-030875	Dipodomys ordii	99.11	4.00e-123	433.00
IUUC-Fca-035832	Felis catus	97.59	4.00e-94	336.00
IUUC-Gmo-039414	Gadus morhua	90.05	2.00e-109	387.00
IUUC-Gga-040694	Gallus gallus	95.76	7.00e-123	432.00
IUUC-Gac-042485	Gasterosteus aculeatus	88.56	4.00e-109	386.00
IUUC-Ggo-044806	Gorilla gorilla	99.11	1.00e-122	432.00
IUUC-Hsa-046245	Homo sapiens	99.11	2.00e-122	431.00
IUUC-Lch-049845	Latimeria chalumnae	90.05	2.00e-109	388.00
IUUC-Loc-052932	Lepisosteus oculatus	91.54	4.00e-111	393.00
IUUC-Mcc-054665	Macaca mulatta	96.43	2.00e-115	407.00
IUUC-Mga-060075	Meleagris gallopavo	95.34	2.00e-122	431.00
IUUC-Mmr-061165	Microcebus murinus	96.43	3.00e-121	427.00
IUUC-Mdo-061825	Monodelphis domestica	97.77	4.00e-120	423.00
IUUC-Mmu-064168	Mus musculus	100.00	2.00e-120	424.00
IUUC-Mpu-066009	Mustela putorius furo	98.66	2.00e-129	454.00
IUUC-Opr-070826	Ochotona princeps	93.49	3.00e-109	387.00
IUUC-Ont-071745	Oreochromis niloticus	90.15	1.00e-110	391.00
IUUC-Oan-073287	Ornithorhynchus anatinus	90.68	5.00e-118	416.00
IUUC-Ocu-074902	Oryctolagus cuniculus	95.63	2.00e-116	411.00
IUUC-Ola-086976	Oryzias latipes	89.39	5.00e-108	383.00
IUUC-Oga-088845	Otolemur garnettii	97.77	4.00e-127	446.00
IUUC-Ptr-090916	Pan troglodytes	99.03	1.00e-117	415.00
IUUC-Psi-093039	Pelodiscus sinensis	93.82	3.00e-88	317.00
IUUC-Pfo-096435	Poecilia formosa	89.55	1.00e-109	388.00
IUUC-Pab-098200	Pongo abelii	99.02	2.00e-111	394.00
IUUC-Pca-100169	Procavia capensis	86.43	5.00e-66	243.00
IUUC-Pva-102875	Pteropus vampyrus	98.18	2.00e-85	307.00
IUUC-Rno-106079	Rattus norvegicus	100.00	2.00e-120	424.00
IUUC-Ssc-115699	Sus scrofa	90.37	4.00e-88	316.00
IUUC-Tgu-117466	Taeniopygia guttata	93.64	1.00e-120	425.00
IUUC-Tru-117589	Takifugu rubripes	84.39	1.00e-103	369.00
IUUC-Tni-120864	Tetraodon nigroviridis	86.07	3.00e-105	374.00
IUUC-Xtr-132285	Xenopus tropicalis	89.08	7.00e-117	412.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence