iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133134

Ensembl Protein ID

ENSXMAP00000010277.1

UniProt Accession

M4A733; M4A733_XIPMA

Genbank Protein ID

ENSXMAP00000010277

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AGAJ01022735

Gene Name

SRC (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000010238.1	ENSXMAT00000010291.1	ENSXMAP00000010277.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-12	47.7	96	156

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeq....degWlkgvkelegkrGlfPenFvek 61
           ++ +lydye+ +  +Lt++kGd +++++++++    +++W+ + + ++g +G +P+n+v+ 
   Q: 96   TFVALYDYESRTVSDLTFRKGDRLQIVNNTKKysfrEGDWWFARSLTTGESGYIPSNYVAP 156
           6789***********************55553333399********************975 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MGAGKSKPKE PGQRSMSLDG TIGTGSDSGH FHHLGPSQQT QTPNRSPAVG TGRPRYQGQH 60
QHAPTNTPEL SLFGGVDHTG TVTSPQRGPL SGGVTTFVAL YDYESRTVSD LTFRKGDRLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NGTGTTACAT 60
CGTGTGTTTG CTCCTGCCTG CCAACGCAGG AGCGATCTTC TGTATCTTGC GCAACATAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

KEGG

xma:102227098

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001713	Ailuropoda melanoleuca	81.31	0.00e+00	918.00
IUUC-Aca-004237	Anolis carolinensis	81.19	0.00e+00	915.00
IUUC-Ame-011887	Astyanax mexicanus	86.26	0.00e+00	960.00
IUUC-Bta-012982	Bos taurus	80.98	0.00e+00	908.00
IUUC-Cja-019995	Callithrix jacchus	81.31	0.00e+00	920.00
IUUC-Cfa-020060	Canis familiaris	81.13	0.00e+00	912.00
IUUC-Cpo-021557	Cavia porcellus	80.58	0.00e+00	901.00
IUUC-Csa-023711	Chlorocebus sabaeus	81.13	0.00e+00	919.00
IUUC-Dre-028491	Danio rerio	84.57	0.00e+00	915.00
IUUC-Dno-029651	Dasypus novemcinctus	79.32	0.00e+00	896.00
IUUC-Ete-033170	Echinops telfairi	87.55	0.00e+00	845.00
IUUC-Eca-033970	Equus caballus	78.40	0.00e+00	870.00
IUUC-Fca-036113	Felis catus	81.13	0.00e+00	912.00
IUUC-Fal-036785	Ficedula albicollis	81.67	0.00e+00	922.00
IUUC-Gga-040899	Gallus gallus	81.31	0.00e+00	914.00
IUUC-Gac-041976	Gasterosteus aculeatus	93.30	0.00e+00	1054.00
IUUC-Hsa-046192	Homo sapiens	81.13	0.00e+00	918.00
IUUC-Itr-049014	Ictidomys tridecemlineatus	81.31	0.00e+00	918.00
IUUC-Lch-049892	Latimeria chalumnae	80.55	0.00e+00	922.00
IUUC-Loc-052812	Lepisosteus oculatus	85.59	0.00e+00	944.00
IUUC-Laf-053977	Loxodonta africana	81.88	0.00e+00	923.00
IUUC-Mcc-055159	Macaca mulatta	79.72	0.00e+00	909.00
IUUC-Mga-060135	Meleagris gallopavo	82.03	0.00e+00	925.00
IUUC-Mmr-061168	Microcebus murinus	79.93	0.00e+00	910.00
IUUC-Mdo-063030	Monodelphis domestica	80.96	0.00e+00	919.00
IUUC-Mmu-063893	Mus musculus	80.76	0.00e+00	916.00
IUUC-Mpu-066411	Mustela putorius furo	81.13	0.00e+00	912.00
IUUC-Mlu-068139	Myotis lucifugus	80.80	0.00e+00	914.00
IUUC-Nle-070178	Nomascus leucogenys	78.80	0.00e+00	875.00
IUUC-Ont-072130	Oreochromis niloticus	96.91	0.00e+00	1099.00
IUUC-Ocu-074403	Oryctolagus cuniculus	81.23	0.00e+00	909.00
IUUC-Ola-086527	Oryzias latipes	94.00	0.00e+00	1060.00
IUUC-Oga-088493	Otolemur garnettii	81.31	0.00e+00	920.00
IUUC-Oar-090279	Ovis aries	81.13	0.00e+00	911.00
IUUC-Ptr-091050	Pan troglodytes	81.13	0.00e+00	918.00
IUUC-Pan-091862	Papio anubis	80.76	0.00e+00	907.00
IUUC-Psi-093071	Pelodiscus sinensis	80.98	0.00e+00	912.00
IUUC-Pfo-096578	Poecilia formosa	99.64	0.00e+00	1147.00
IUUC-Pab-097902	Pongo abelii	79.89	0.00e+00	911.00
IUUC-Rno-105847	Rattus norvegicus	80.80	0.00e+00	917.00
IUUC-Sha-107539	Sarcophilus harrisii	81.34	0.00e+00	914.00
IUUC-Stu-112331	Solanum tuberosum	32.80	4.00e-23	103.00
IUUC-Ssc-115762	Sus scrofa	81.34	0.00e+00	916.00
IUUC-Tru-117854	Takifugu rubripes	94.00	0.00e+00	1050.00
IUUC-Tni-120843	Tetraodon nigroviridis	94.55	0.00e+00	1082.00
IUUC-Ttr-128702	Tursiops truncatus	76.41	0.00e+00	845.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence