iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023960

Ensembl Protein ID

ENSCSAP00000004087.1

UniProt Accession

A0A0D9R648; A0A0D9R648_CHLSB

Genbank Protein ID

ENSCSAP00000004087

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01146527

Gene Name

AIRE

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000007836.1	ENSCSAT00000005871.1	ENSCSAP00000004087.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.00e-17	64.0	297	341

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           + C+vC++gge    l++C+ C ++fH aCl+++  +e p+ + w C+ C 
   Q: 297  DECAVCRDGGE----LICCDGCPRAFHLACLSPP-LQEIPSGT-WRCSGCL 341
           57*********....*******************.*******6.******6 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MAADAALRRL LRLHRTEIAV AVDSAFPLLH ALADHDVVPE DKFQETLRLK EKEGCPQAFH 60
ALLSWLLTQD STVILDFWRV LFKDYNLERY GRLQPILDSF PKDVDLSQSR KGRKLPTIPK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCGG ACGCAGCCCT GCGCCGGCTT CTGAGGCTGC ACCGCACGGA GATCGCGGTG 60
GCCGTGGACA GCGCCTTCCC CCTGCTGCAC GCGCTGGCCG ACCACGACGT GGTCCCCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008087--AIRE
IPR004865--HSR_dom
IPR000770--SAND_dom
IPR010919--SAND_dom-like
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51414--HSR
PS50864--SAND
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF03172--HSR
PF00628--PHD
PF01342--SAND

PRINTS

PR01711--AIREGULATOR

SMART

SM00249--PHD
SM00258--SAND

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0003682--F:chromatin binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0045182--F:translation regulator activity
GO:0008270--F:zinc ion binding
GO:0002509--P:central tolerance induction to self antigen
GO:0032602--P:chemokine production
GO:0006959--P:humoral immune response
GO:0045060--P:negative thymic T cell selection
GO:0002458--P:peripheral T cell tolerance induction
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:2000410--P:regulation of thymocyte migration
GO:0097536--P:thymus epithelium morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001612	Ailuropoda melanoleuca	77.18	4.00e-180	624.00
IUUC-Aca-004543	Anolis carolinensis	69.35	8.00e-24	101.00
IUUC-Bta-012988	Bos taurus	76.01	0.00e+00	654.00
IUUC-Bci-013636	Botrytis cinerea	26.36	4.00e-11	64.30
IUUC-Bdi-014663	Brachypodium distachyon	50.00	6.00e-14	73.60
IUUC-Cja-019486	Callithrix jacchus	86.40	3.00e-119	421.00
IUUC-Cfa-021069	Canis familiaris	74.77	4.00e-176	611.00
IUUC-Cpo-021649	Cavia porcellus	70.20	2.00e-159	555.00
IUUC-Dre-028583	Danio rerio	40.73	8.00e-56	211.00
IUUC-Dno-029869	Dasypus novemcinctus	64.91	9.00e-131	460.00
IUUC-Dor-030263	Dipodomys ordii	86.02	4.00e-45	174.00
IUUC-Ete-032778	Echinops telfairi	91.84	1.00e-49	191.00
IUUC-Eca-034328	Equus caballus	75.65	7.00e-175	607.00
IUUC-Fca-035400	Felis catus	71.32	2.00e-167	581.00
IUUC-Fal-036644	Ficedula albicollis	50.92	2.00e-69	256.00
IUUC-Ggo-045250	Gorilla gorilla	92.12	0.00e+00	764.00
IUUC-Hsa-046603	Homo sapiens	92.50	0.00e+00	764.00
IUUC-Hvu-047073	Hordeum vulgare	58.70	1.00e-13	72.80
IUUC-Itr-048977	Ictidomys tridecemlineatus	73.80	1.00e-172	599.00
IUUC-Lch-050310	Latimeria chalumnae	42.91	7.00e-97	347.00
IUUC-Loc-052508	Lepisosteus oculatus	49.24	2.00e-78	286.00
IUUC-Laf-054028	Loxodonta africana	67.99	3.00e-157	548.00
IUUC-Mcc-054935	Macaca mulatta	96.06	0.00e+00	834.00
IUUC-Mga-059318	Meleagris gallopavo	41.41	4.00e-54	204.00
IUUC-Mmr-061557	Microcebus murinus	65.61	4.00e-144	504.00
IUUC-Mdo-062475	Monodelphis domestica	50.37	4.00e-120	424.00
IUUC-Mmu-063994	Mus musculus	70.63	0.00e+00	685.00
IUUC-Mpu-066347	Mustela putorius furo	77.06	0.00e+00	684.00
IUUC-Mlu-068239	Myotis lucifugus	61.98	1.00e-89	323.00
IUUC-Nle-069544	Nomascus leucogenys	84.85	1.00e-28	119.00
IUUC-Opr-071199	Ochotona princeps	75.41	5.00e-73	268.00
IUUC-Ont-072571	Oreochromis niloticus	78.26	2.00e-19	90.50
IUUC-Oan-073739	Ornithorhynchus anatinus	55.37	1.00e-146	513.00
IUUC-Ogl-077865	Oryza glaberrima	42.42	9.00e-13	69.70
IUUC-Olo-080499	Oryza longistaminata	42.42	9.00e-13	70.10
IUUC-Opu-083209	Oryza punctata	42.42	1.00e-12	69.70
IUUC-Ola-086528	Oryzias latipes	35.93	1.00e-41	164.00
IUUC-Oga-088353	Otolemur garnettii	79.32	0.00e+00	699.00
IUUC-Oar-090065	Ovis aries	77.14	5.00e-148	517.00
IUUC-Ptr-091347	Pan troglodytes	92.31	0.00e+00	740.00
IUUC-Pan-092423	Papio anubis	96.84	0.00e+00	824.00
IUUC-Psi-093798	Pelodiscus sinensis	54.53	8.00e-136	477.00
IUUC-Pfo-096145	Poecilia formosa	71.70	8.00e-21	95.10
IUUC-Pab-098369	Pongo abelii	90.46	1.00e-132	466.00
IUUC-Pca-100537	Procavia capensis	72.90	1.00e-178	619.00
IUUC-Ppe-101215	Prunus persica	60.42	5.00e-14	73.20
IUUC-Pva-102639	Pteropus vampyrus	75.61	8.00e-180	623.00
IUUC-Rno-105285	Rattus norvegicus	69.09	0.00e+00	661.00
IUUC-Sha-107159	Sarcophilus harrisii	50.28	1.00e-124	439.00
IUUC-Sit-110355	Setaria italica	48.57	3.00e-13	71.20
IUUC-Sbi-113930	Sorghum bicolor	60.42	4.00e-13	70.90
IUUC-Ssc-115773	Sus scrofa	73.54	0.00e+00	626.00
IUUC-Tgu-116922	Taeniopygia guttata	49.09	2.00e-68	252.00
IUUC-Tru-118263	Takifugu rubripes	31.31	1.00e-58	221.00
IUUC-Tsy-119270	Tarsius syrichta	74.38	9.00e-95	340.00
IUUC-Tni-120138	Tetraodon nigroviridis	30.27	4.00e-56	212.00
IUUC-Tca-121757	Theobroma cacao	59.18	4.00e-14	74.70
IUUC-Tae-124715	Triticum aestivum	58.70	1.00e-13	72.80
IUUC-Tur-126422	Triticum urartu	55.32	6.00e-12	67.40
IUUC-Tme-127204	Tuber melanosporum	55.32	7.00e-14	73.20
IUUC-Tbe-128077	Tupaia belangeri	70.76	0.00e+00	643.00
IUUC-Ttr-128781	Tursiops truncatus	80.98	8.00e-75	274.00
IUUC-Xma-133054	Xiphophorus maculatus	30.44	2.00e-57	216.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence