iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035400

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02044469

Gene Name

AIRE

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000007933.3	ENSFCAT00000007935.3	ENSFCAP00000007349.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.90e-09	36.3	298	341

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkC 51
           + C+vC++gge    l++C+ C ++fH aCl+++  +e p+ + w C +C
   Q: 298  DECAVCRDGGE----LICCDGCPRAFHLACLSPP-LREIPSGT-WRCYSC 341
           57*********....*******************.*******6.****** PP

Organism

Felis catus

Protein Sequence
(Fasta)

QAGGDTVLRH LLRLYRTEIA MAVDGAFPLL HALADHDVVP EDKFQETLRL KEKEGCPQAF 60
HALLSWLLTQ DAAAILDFWR VLFKDYNLER YARLQPILDC FPKDVDLSQP RKGRKPPTGP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGCAGGTG GGGACACGGT GCTTCGTCAC CTCCTGAGGC TGTACCGCAC TGAGATCGCC 60
ATGGCTGTGG ACGGCGCCTT CCCGCTGCTG CACGCGCTGG CTGACCACGA CGTGGTCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008087--AIRE
IPR004865--HSR_dom
IPR000770--SAND_dom
IPR010919--SAND_dom-like
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51414--HSR
PS50864--SAND
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF03172--HSR
PF00628--PHD
PF01342--SAND

PRINTS

PR01711--AIREGULATOR

SMART

SM00249--PHD
SM00258--SAND

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0042393--F:histone binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003712--F:transcription cofactor activity
GO:0045182--F:translation regulator activity
GO:0008270--F:zinc ion binding
GO:0002509--P:central tolerance induction to self antigen
GO:0032602--P:chemokine production
GO:0006959--P:humoral immune response
GO:0006955--P:immune response
GO:0045060--P:negative thymic T cell selection
GO:0002458--P:peripheral T cell tolerance induction
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:2000410--P:regulation of thymocyte migration
GO:0097536--P:thymus epithelium morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001612	Ailuropoda melanoleuca	78.70	0.00e+00	678.00
IUUC-Aca-004543	Anolis carolinensis	67.74	7.00e-24	101.00
IUUC-Bta-012988	Bos taurus	72.40	0.00e+00	657.00
IUUC-Bdi-014663	Brachypodium distachyon	59.57	2.00e-13	71.60
IUUC-Cja-019486	Callithrix jacchus	64.67	5.00e-77	280.00
IUUC-Cfa-021069	Canis familiaris	80.43	0.00e+00	644.00
IUUC-Cpo-021649	Cavia porcellus	63.41	1.00e-159	556.00
IUUC-Csa-023960	Chlorocebus sabaeus	73.56	9.00e-164	570.00
IUUC-Cne-026966	Cryptococcus neoformans	40.40	1.00e-11	64.70
IUUC-Dre-028583	Danio rerio	41.19	2.00e-59	223.00
IUUC-Dno-029869	Dasypus novemcinctus	65.48	1.00e-137	483.00
IUUC-Dor-030263	Dipodomys ordii	84.04	1.00e-45	176.00
IUUC-Ete-032778	Echinops telfairi	89.09	3.00e-54	206.00
IUUC-Eca-034328	Equus caballus	76.45	0.00e+00	667.00
IUUC-Fal-036644	Ficedula albicollis	50.88	2.00e-76	280.00
IUUC-Fox-038014	Fusarium oxysporum	38.30	2.00e-08	55.50
IUUC-Ggo-045250	Gorilla gorilla	72.80	2.00e-158	551.00
IUUC-Hsa-046603	Homo sapiens	73.55	3.00e-158	551.00
IUUC-Hvu-047073	Hordeum vulgare	58.70	1.00e-13	72.40
IUUC-Itr-048977	Ictidomys tridecemlineatus	67.20	2.00e-149	522.00
IUUC-Lch-050310	Latimeria chalumnae	48.49	3.00e-91	328.00
IUUC-Loc-052508	Lepisosteus oculatus	48.72	4.00e-83	301.00
IUUC-Lma-053053	Leptosphaeria maculans	36.54	1.00e-13	72.00
IUUC-Laf-054028	Loxodonta africana	62.65	9.00e-155	540.00
IUUC-Mcc-054935	Macaca mulatta	73.63	2.00e-168	585.00
IUUC-Mga-059318	Meleagris gallopavo	45.45	4.00e-60	224.00
IUUC-Mmr-061557	Microcebus murinus	58.79	2.00e-123	436.00
IUUC-Mdo-062475	Monodelphis domestica	47.47	4.00e-113	401.00
IUUC-Mmu-063994	Mus musculus	63.49	7.00e-171	593.00
IUUC-Mpu-066347	Mustela putorius furo	78.21	0.00e+00	718.00
IUUC-Mlu-068239	Myotis lucifugus	60.74	2.00e-77	282.00
IUUC-Nle-069544	Nomascus leucogenys	88.89	9.00e-25	106.00
IUUC-Opr-071199	Ochotona princeps	73.12	5.00e-76	278.00
IUUC-Ont-072571	Oreochromis niloticus	34.54	9.00e-39	154.00
IUUC-Oan-073739	Ornithorhynchus anatinus	53.36	2.00e-144	505.00
IUUC-Ogl-077865	Oryza glaberrima	48.21	1.00e-12	69.30
IUUC-Olo-080499	Oryza longistaminata	48.21	1.00e-12	69.70
IUUC-Opu-083209	Oryza punctata	48.21	1.00e-12	69.30
IUUC-Ola-086528	Oryzias latipes	34.62	1.00e-40	160.00
IUUC-Oga-088353	Otolemur garnettii	72.61	0.00e+00	656.00
IUUC-Oar-090065	Ovis aries	78.96	6.00e-158	550.00
IUUC-Ptr-091347	Pan troglodytes	73.73	8.00e-152	530.00
IUUC-Pan-092423	Papio anubis	71.57	6.00e-161	560.00
IUUC-Psi-093798	Pelodiscus sinensis	50.00	9.00e-118	417.00
IUUC-Pfo-096145	Poecilia formosa	44.68	7.00e-21	95.10
IUUC-Pab-098369	Pongo abelii	80.98	3.00e-127	447.00
IUUC-Pca-100537	Procavia capensis	67.10	2.00e-159	555.00
IUUC-Ppe-101215	Prunus persica	60.42	2.00e-14	74.30
IUUC-Pva-102639	Pteropus vampyrus	73.02	2.00e-179	621.00
IUUC-Pte-104185	Pyrenophora teres	46.00	9.00e-13	70.10
IUUC-Pyt-104775	Pyrenophora triticirepentis	46.00	8.00e-13	69.70
IUUC-Rno-105285	Rattus norvegicus	66.25	4.00e-175	607.00
IUUC-Sha-107159	Sarcophilus harrisii	46.10	1.00e-110	393.00
IUUC-Sit-110355	Setaria italica	58.33	2.00e-12	68.90
IUUC-Sbi-113930	Sorghum bicolor	58.33	1.00e-12	68.90
IUUC-Ssc-115773	Sus scrofa	73.63	0.00e+00	637.00
IUUC-Tgu-116922	Taeniopygia guttata	48.53	1.00e-74	272.00
IUUC-Tru-118263	Takifugu rubripes	31.17	8.00e-56	211.00
IUUC-Tsy-119270	Tarsius syrichta	69.72	8.00e-93	333.00
IUUC-Tni-120138	Tetraodon nigroviridis	30.43	2.00e-55	210.00
IUUC-Tca-121757	Theobroma cacao	52.83	1.00e-13	73.20
IUUC-Tae-124715	Triticum aestivum	58.70	1.00e-13	72.40
IUUC-Tur-126422	Triticum urartu	53.19	3.00e-12	68.20
IUUC-Tme-127204	Tuber melanosporum	50.88	3.00e-14	74.30
IUUC-Tbe-128077	Tupaia belangeri	65.65	2.00e-173	601.00
IUUC-Ttr-128781	Tursiops truncatus	78.92	1.00e-75	276.00
IUUC-Xma-133054	Xiphophorus maculatus	34.47	4.00e-44	172.00
IUUC-Yli-134436	Yarrowia lipolytica	40.79	8.00e-12	65.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence