iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066750

Ensembl Protein ID

ENSMPUP00000003702.1

UniProt Accession

M3XXA2; M3XXA2_MUSPF

Genbank Protein ID

ENSMPUP00000003702

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01011266

Gene Name

KLHL22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000003732.1	ENSMPUT00000003770.1	ENSMPUP00000003702.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.00e-19	69.7	51	115
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	9.70e-08	31.3	150	179

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lvv+g++++ah+i Laas+++F+ +f ++l+e++ +++v i++v++ ++ ++l+F+Yt++l++
   Q: 51   DVVLVVEGRHIEAHRILLAASCDYFRGMFAGGLKEME-QEEVLIHGVSYNAMCQILHFIYTSELEL 115
           9***********************************8.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
           eN l+++r+A+l+d+++L ++ +++ilk+F
   Q: 150  ENILDVYRLAELFDLSRLTEQLDTYILKNF 179
           8***************************** PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MAEEQEFTQL CKLPVQPSHP HCVNNTYRSA QHSQALLRGL LALRDSGILF DVVLVVEGRH 60
IEAHRILLAA SCDYFRGMFA GGLKEMEQEE VLIHGVSYNA MCQILHFIYT SELELSLSNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGGGTGCT TTTATTTCCC TTTTACCATT TGAGGAACCT GAGACTCAGG TTGGTCATGT 60
GGTGAGTCCA TGGTAGGGCT GGGGCCCCCA CTGAAGTCAG TCTGTCTCTG GAACCCCTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005813--C:centrosome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:0005827--C:polar microtubule
GO:0051301--P:cell division
GO:0000070--P:mitotic sister chromatid segregation
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002097	Ailuropoda melanoleuca	98.74	0.00e+00	1248.00
IUUC-Apl-004081	Anas platyrhynchos	77.59	0.00e+00	1023.00
IUUC-Aca-005015	Anolis carolinensis	65.97	0.00e+00	845.00
IUUC-Ame-011712	Astyanax mexicanus	60.03	0.00e+00	724.00
IUUC-Bta-012594	Bos taurus	94.01	0.00e+00	1226.00
IUUC-Cja-019752	Callithrix jacchus	97.03	0.00e+00	1031.00
IUUC-Cfa-020884	Canis familiaris	99.21	0.00e+00	1312.00
IUUC-Cpo-021711	Cavia porcellus	96.69	0.00e+00	1262.00
IUUC-Csa-023211	Chlorocebus sabaeus	98.11	0.00e+00	1296.00
IUUC-Dre-028395	Danio rerio	60.23	0.00e+00	754.00
IUUC-Dno-030096	Dasypus novemcinctus	94.36	0.00e+00	1231.00
IUUC-Dor-030709	Dipodomys ordii	96.49	0.00e+00	711.00
IUUC-Eca-033388	Equus caballus	98.26	0.00e+00	1302.00
IUUC-Eeu-034616	Erinaceus europaeus	85.33	0.00e+00	1096.00
IUUC-Fca-035815	Felis catus	99.05	0.00e+00	1310.00
IUUC-Fal-037311	Ficedula albicollis	79.84	0.00e+00	1004.00
IUUC-Gmo-039571	Gadus morhua	52.43	4.00e-158	551.00
IUUC-Gga-040992	Gallus gallus	77.43	0.00e+00	1023.00
IUUC-Gac-042041	Gasterosteus aculeatus	55.49	0.00e+00	684.00
IUUC-Ggo-045141	Gorilla gorilla	92.43	0.00e+00	1199.00
IUUC-Hsa-045984	Homo sapiens	98.26	0.00e+00	1299.00
IUUC-Itr-048890	Ictidomys tridecemlineatus	97.95	0.00e+00	1278.00
IUUC-Lch-049700	Latimeria chalumnae	60.69	0.00e+00	731.00
IUUC-Loc-052141	Lepisosteus oculatus	61.67	0.00e+00	811.00
IUUC-Laf-053487	Loxodonta africana	95.71	0.00e+00	1232.00
IUUC-Mcc-054682	Macaca mulatta	97.86	0.00e+00	1024.00
IUUC-Meu-055937	Macropus eugenii	74.92	0.00e+00	972.00
IUUC-Mga-059953	Meleagris gallopavo	77.43	0.00e+00	1023.00
IUUC-Mmr-061743	Microcebus murinus	97.32	0.00e+00	1263.00
IUUC-Mdo-062328	Monodelphis domestica	82.92	0.00e+00	1092.00
IUUC-Mmu-063979	Mus musculus	94.42	0.00e+00	1218.00
IUUC-Mlu-066960	Myotis lucifugus	96.06	0.00e+00	1246.00
IUUC-Nle-069690	Nomascus leucogenys	98.20	0.00e+00	1144.00
IUUC-Opr-071059	Ochotona princeps	90.55	0.00e+00	1155.00
IUUC-Ont-072004	Oreochromis niloticus	57.97	0.00e+00	684.00
IUUC-Oan-073172	Ornithorhynchus anatinus	63.41	0.00e+00	742.00
IUUC-Ocu-074310	Oryctolagus cuniculus	95.45	2.00e-154	537.00
IUUC-Ola-086599	Oryzias latipes	57.54	0.00e+00	698.00
IUUC-Oga-087980	Otolemur garnettii	97.00	0.00e+00	1261.00
IUUC-Oar-089956	Ovis aries	78.99	0.00e+00	920.00
IUUC-Ptr-090598	Pan troglodytes	98.03	0.00e+00	1147.00
IUUC-Pan-092387	Papio anubis	97.67	0.00e+00	1023.00
IUUC-Psi-093484	Pelodiscus sinensis	79.15	0.00e+00	1053.00
IUUC-Pma-094224	Petromyzon marinus	49.27	1.00e-170	593.00
IUUC-Pfo-096149	Poecilia formosa	57.63	0.00e+00	711.00
IUUC-Pab-098097	Pongo abelii	98.11	0.00e+00	1298.00
IUUC-Pca-100118	Procavia capensis	95.95	0.00e+00	704.00
IUUC-Pva-103174	Pteropus vampyrus	96.20	1.00e-156	546.00
IUUC-Rno-105350	Rattus norvegicus	94.64	0.00e+00	1203.00
IUUC-Sha-106817	Sarcophilus harrisii	83.52	6.00e-136	478.00
IUUC-Sar-113490	Sorex araneus	96.21	0.00e+00	650.00
IUUC-Ssc-115827	Sus scrofa	96.06	0.00e+00	1254.00
IUUC-Tgu-116748	Taeniopygia guttata	81.94	0.00e+00	896.00
IUUC-Tru-118644	Takifugu rubripes	58.01	0.00e+00	692.00
IUUC-Tsy-118888	Tarsius syrichta	91.04	0.00e+00	1043.00
IUUC-Tni-120060	Tetraodon nigroviridis	54.28	4.00e-174	604.00
IUUC-Ttr-129183	Tursiops truncatus	95.52	0.00e+00	1118.00
IUUC-Xtr-132780	Xenopus tropicalis	68.53	0.00e+00	901.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence