iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012478

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02045596

Gene Name

ZNRF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000022036.4	ENSBTAT00000028780.5	ENSBTAP00000028780.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.80e-06	26.1	158	199

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCle +   ++++v pC H fh++C+  w        ++ +CP Cr
   Q: 158  CAICLEKYidGEELRVIPCTHRFHRKCVDPW------LLQHHTCPHCR 199
           ********66334******************......9999******8 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

CSFSLSQAKR AVQRGATAVI FDVSENPEAI DQLNQGSEDP LKRPVVYVKG ADAIKLMNIV 60
NKQKVARARI QHRPPRQPTE YFDMGIFLAF FVVVSLVCLI LLVKIKLKQR RSQNSMNRLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCTCTTTCT CACTCTCCCA GGCCAAGCGA GCCGTGCAGC GGGGAGCCAC CGCAGTCATC 60
TTCGATGTGT CCGAGAACCC AGAAGCTATT GACCAGGTAA GCTCCTGGGG CCAGGCCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001916	Ailuropoda melanoleuca	69.74	0.00e+00	808.00
IUUC-Apl-004188	Anas platyrhynchos	56.46	0.00e+00	642.00
IUUC-Aly-005850	Arabidopsis lyrata	41.98	2.00e-14	71.20
IUUC-Ath-007372	Arabidopsis thaliana	41.98	8.00e-14	69.30
IUUC-Ame-011764	Astyanax mexicanus	52.25	2.00e-148	520.00
IUUC-Bdi-014078	Brachypodium distachyon	62.79	2.00e-12	65.10
IUUC-Bol-016217	Brassica oleracea	55.32	2.00e-13	68.20
IUUC-Bra-017407	Brassica rapa	55.32	2.00e-13	68.20
IUUC-Cja-019504	Callithrix jacchus	69.03	0.00e+00	833.00
IUUC-Cfa-020048	Canis familiaris	68.67	0.00e+00	804.00
IUUC-Cpo-021725	Cavia porcellus	65.73	4.00e-104	372.00
IUUC-Csa-023586	Chlorocebus sabaeus	67.90	0.00e+00	773.00
IUUC-Cho-024867	Choloepus hoffmanni	64.63	7.00e-109	388.00
IUUC-Cin-025569	Ciona intestinalis	44.39	2.00e-40	160.00
IUUC-Dre-027553	Danio rerio	51.71	8.00e-145	508.00
IUUC-Dno-029370	Dasypus novemcinctus	65.31	0.00e+00	741.00
IUUC-Dor-030816	Dipodomys ordii	63.06	7.00e-146	511.00
IUUC-Ete-033060	Echinops telfairi	80.61	2.00e-80	293.00
IUUC-Eca-034044	Equus caballus	68.97	0.00e+00	843.00
IUUC-Eeu-034591	Erinaceus europaeus	60.65	1.00e-89	324.00
IUUC-Fca-036000	Felis catus	70.29	0.00e+00	823.00
IUUC-Fal-037147	Ficedula albicollis	57.58	0.00e+00	656.00
IUUC-Gga-041243	Gallus gallus	52.77	3.00e-143	501.00
IUUC-Gac-041340	Gasterosteus aculeatus	39.89	1.00e-34	140.00
IUUC-Ggo-044953	Gorilla gorilla	69.16	0.00e+00	802.00
IUUC-Hsa-046484	Homo sapiens	68.91	0.00e+00	803.00
IUUC-Itr-048470	Ictidomys tridecemlineatus	65.68	0.00e+00	783.00
IUUC-Lch-050004	Latimeria chalumnae	46.77	2.00e-115	409.00
IUUC-Loc-051830	Lepisosteus oculatus	52.10	4.00e-134	472.00
IUUC-Laf-053975	Loxodonta africana	65.02	0.00e+00	752.00
IUUC-Mcc-055302	Macaca mulatta	68.15	0.00e+00	768.00
IUUC-Meu-056263	Macropus eugenii	59.97	4.00e-120	425.00
IUUC-Mga-059706	Meleagris gallopavo	56.73	0.00e+00	652.00
IUUC-Mmr-061372	Microcebus murinus	66.54	0.00e+00	763.00
IUUC-Mdo-062651	Monodelphis domestica	94.09	3.00e-92	332.00
IUUC-Mmu-064339	Mus musculus	63.35	0.00e+00	729.00
IUUC-Mac-065574	Musa acuminata	54.90	2.00e-13	68.20
IUUC-Mpu-066211	Mustela putorius furo	68.02	0.00e+00	815.00
IUUC-Mlu-067058	Myotis lucifugus	70.95	0.00e+00	819.00
IUUC-Nle-069886	Nomascus leucogenys	68.20	0.00e+00	778.00
IUUC-Opr-070218	Ochotona princeps	62.16	0.00e+00	709.00
IUUC-Ont-072483	Oreochromis niloticus	48.35	8.00e-142	497.00
IUUC-Oan-073718	Ornithorhynchus anatinus	57.51	4.00e-166	578.00
IUUC-Ocu-073847	Oryctolagus cuniculus	58.65	9.00e-170	590.00
IUUC-Ola-087358	Oryzias latipes	48.86	3.00e-140	492.00
IUUC-Oga-088362	Otolemur garnettii	65.60	0.00e+00	780.00
IUUC-Oar-090197	Ovis aries	78.02	2.00e-127	449.00
IUUC-Ptr-091350	Pan troglodytes	69.03	0.00e+00	803.00
IUUC-Pan-091700	Papio anubis	68.02	0.00e+00	761.00
IUUC-Psi-093301	Pelodiscus sinensis	56.92	9.00e-179	620.00
IUUC-Pfo-096917	Poecilia formosa	49.53	3.00e-135	476.00
IUUC-Pab-097932	Pongo abelii	68.97	0.00e+00	826.00
IUUC-Pop-098859	Populus trichocarpa	52.83	1.00e-14	72.40
IUUC-Pca-101054	Procavia capensis	66.84	3.00e-150	525.00
IUUC-Pva-102879	Pteropus vampyrus	69.16	0.00e+00	807.00
IUUC-Pgr-103645	Puccinia graminis	51.16	3.00e-09	55.10
IUUC-Sha-106507	Sarcophilus harrisii	94.12	2.00e-93	336.00
IUUC-Sit-110656	Setaria italica	67.44	8.00e-13	66.60
IUUC-Stu-112500	Solanum tuberosum	62.79	8.00e-13	66.60
IUUC-Sar-113182	Sorex araneus	89.91	2.00e-93	337.00
IUUC-Sbi-114367	Sorghum bicolor	49.23	8.00e-12	63.50
IUUC-Ssc-115966	Sus scrofa	68.55	0.00e+00	813.00
IUUC-Tgu-116864	Taeniopygia guttata	46.66	1.00e-105	377.00
IUUC-Tru-118502	Takifugu rubripes	48.06	1.00e-127	450.00
IUUC-Tsy-119210	Tarsius syrichta	65.22	0.00e+00	731.00
IUUC-Tni-120344	Tetraodon nigroviridis	43.18	1.00e-40	160.00
IUUC-Tca-121005	Theobroma cacao	55.10	4.00e-13	68.20
IUUC-Tbe-127735	Tupaia belangeri	100.00	3.00e-46	180.00
IUUC-Ttr-128714	Tursiops truncatus	81.82	2.00e-137	483.00
IUUC-Xtr-132280	Xenopus tropicalis	47.37	6.00e-117	415.00
IUUC-Xma-134192	Xiphophorus maculatus	51.21	9.00e-136	477.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence