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Tag Content
UUCD2 ID IUUC-Aml-001999
UUCD1 version UUC-AiM-01054
Ensembl Protein ID ENSAMEP00000013508.1
UniProt Accession G1M2E7; G1M2E7_AILME
Genbank Protein ID ENSAMEP00000013508
Protein Name Uncharacterized protein
Genbank Nucleotide ID ACTA01098591
Gene Name USP19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000012785.1 ENSAMET00000014070.1 ENSAMEP00000013508.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 4.60e-115 384.5 650 1367
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl NlgNtC+mNSv+Q+Lsn++elr+++++ +++ ++n +np ++ g+l+  ++ l+++lwk++++a++p++l+++++++a++f+g
   Q: 650  TGLVNLGNTCFMNSVIQSLSNTRELRDFFHDrSFEAEINYNNPLGTGGRLAIGFAVLLRALWKGTHHAFQPSKLKAIVASKASQFTG 736
           7*****************************999****************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           y+q+DaqEf+aflld+l+e+l++ +nkp++e+ ++d   ++de     a++++k++n+s+i+dlFqgq+ks+++c+ c++vs +++p
   Q: 737  YAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSD--GRPDEvvaeeAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCAKVSITFDP 821
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           fl+l++p+p+k++  +                                                                       
   Q: 822  FLYLPVPLPQKQKVLPVfyfarephskpikflvsiskenssasevleslsqsvhvksenlrlaeviknrfhrvflpshsldtvspsd 908
           ************87666********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 909  tllcfellppelakervvvlevqqrpqvpsvpiskcaacqrkqqsedeklkrctrcyrvgycnqlcqkthwpdhkglcrpenigypf 995
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 996  lvsvpasrltyarlaqllegyarysvsvfqppfqpgrmalesqgpgcttllstssleagdserdliqppelqlvtpvaegdagvpra 1082
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1083 waapdrgpvpstsgvssevlaggpvevgslpaservsrpeaavpgyqhpseamnahtpqffiykidasnreqrledkgdtplelged 1169
           *************************************************************************************** PP
   S: 186  ..........................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevL 230
                                                     +l++cL+ ft++e l  e+++yc++ck+++ea+k+l l++lP+vL
   Q: 1170 cslalvwrnnerlqefvlvaskelecaedpgsageaaraghfTLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVL 1256
           *************************************************************************************** PP
   S: 231  ilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk........Wll 308
           i++LkRfsf++  +++ kin+ vefp + Ldls+fc+ ++e+q    +Y+L+av++H+G++ +GHY+a+++  +++        W l
   Q: 1257 IVQLKRFSFRSFIWRD-KINDLVEFPVRnLDLSKFCIGQKEEQ--LPSYDLYAVINHYGGMIGGHYTACARLPNDRssqrsdvgWRL 1340
           ************8886.**********9**********99888..9**************************544445566777*** PP
   S: 309  fdDskVtevkeeevleetgstaYvlfYkrr 338
           fdDs+Vt+v+e++v++   + aYvlfY+rr
   Q: 1341 FDDSTVTTVDESQVVT---RYAYVLFYRRR 1367
           ****************...********996 PP
   
Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
PEPRAGCQGP KRAGGGGLAR LSVPCWRIWP QRVAKIAGPG RKRRSPDPDA VADPGALWLS 60
TKRLKMSGGA SATGPRRGPP GLEEATSKKK QKDRANQESK DGDPRRDTER RTHSRLGRAS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aml-001999|DUB,USP|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCGGAACCGA GAGCGGGTTG CCAGGGCCCT AAGAGGGCTG GCGGCGGCGG CCTCGCTCGG 60
TGAGTGGGAC GGGCCGCAAC TGGCCTGTCT GGCTGGAGCC AGGGAGGCCG CGACGGGGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aml-001999|DUB,USP|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR007052--CS_dom
IPR008978--HSP20-like_chaperone
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR002893--Znf_MYND
PROSITE

PS51203--CS
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS01360--ZF_MYND_1
PS50865--ZF_MYND_2
Pfam

PF04969--CS
PF00443--UCH
PF01753--zf-MYND
Gene Ontology

GO:0005829--C:cytosol
GO:0005789--C:endoplasmic reticulum membrane
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1901799--P:negative regulation of proteasomal protein catabolic process
GO:0048642--P:negative regulation of skeletal muscle tissue development
GO:0050821--P:protein stabilization
GO:1900037--P:regulation of cellular response to hypoxia
GO:1904292--P:regulation of ERAD pathway
GO:0030433--P:ubiquitin-dependent ERAD pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-003368 Anas platyrhynchos 67.84 0.00e+00 1774.00
IUUC-Aca-004267 Anolis carolinensis 65.60 0.00e+00 1684.00
IUUC-Ame-010970 Astyanax mexicanus 70.15 0.00e+00 1344.00
IUUC-Bta-012905 Bos taurus 92.41 0.00e+00 2512.00
IUUC-Cel-018257 Caenorhabditis elegans 43.00 4.00e-92 333.00
IUUC-Cja-018789 Callithrix jacchus 90.13 0.00e+00 2353.00
IUUC-Cfa-021004 Canis familiaris 95.72 0.00e+00 2622.00
IUUC-Cpo-021529 Cavia porcellus 87.56 0.00e+00 2246.00
IUUC-Csa-024035 Chlorocebus sabaeus 89.41 0.00e+00 2385.00
IUUC-Cho-025036 Choloepus hoffmanni 82.87 0.00e+00 1221.00
IUUC-Cin-025451 Ciona intestinalis 43.15 7.00e-86 312.00
IUUC-Csv-025931 Ciona savignyi 35.86 2.00e-109 389.00
IUUC-Dre-028556 Danio rerio 70.11 0.00e+00 1321.00
IUUC-Dno-029240 Dasypus novemcinctus 86.87 0.00e+00 2162.00
IUUC-Dor-030495 Dipodomys ordii 95.27 0.00e+00 1197.00
IUUC-Ete-032741 Echinops telfairi 91.81 0.00e+00 1860.00
IUUC-Eca-033661 Equus caballus 92.82 0.00e+00 2385.00
IUUC-Eeu-034648 Erinaceus europaeus 91.70 0.00e+00 831.00
IUUC-Fca-035646 Felis catus 96.66 0.00e+00 2605.00
IUUC-Fal-037094 Ficedula albicollis 66.98 0.00e+00 1725.00
IUUC-Gmo-038869 Gadus morhua 71.78 0.00e+00 847.00
IUUC-Gga-041170 Gallus gallus 64.56 0.00e+00 1663.00
IUUC-Gac-041901 Gasterosteus aculeatus 65.93 0.00e+00 1320.00
IUUC-Ggo-044708 Gorilla gorilla 90.51 0.00e+00 2346.00
IUUC-Hsa-046791 Homo sapiens 94.54 0.00e+00 1997.00
IUUC-Itr-048892 Ictidomys tridecemlineatus 89.14 0.00e+00 2264.00
IUUC-Lch-050456 Latimeria chalumnae 52.66 0.00e+00 1189.00
IUUC-Loc-052861 Lepisosteus oculatus 59.79 0.00e+00 1147.00
IUUC-Laf-053788 Loxodonta africana 90.85 0.00e+00 2253.00
IUUC-Mcc-055693 Macaca mulatta 89.67 0.00e+00 2427.00
IUUC-Meu-055921 Macropus eugenii 78.95 0.00e+00 1472.00
IUUC-Mga-059879 Meleagris gallopavo 67.35 0.00e+00 1719.00
IUUC-Mmr-060802 Microcebus murinus 92.08 0.00e+00 2395.00
IUUC-Mdo-061856 Monodelphis domestica 77.32 0.00e+00 1561.00
IUUC-Mmu-063874 Mus musculus 88.15 0.00e+00 2248.00
IUUC-Mpu-066166 Mustela putorius furo 96.61 0.00e+00 2640.00
IUUC-Nle-070161 Nomascus leucogenys 89.91 0.00e+00 2399.00
IUUC-Opr-071015 Ochotona princeps 93.77 0.00e+00 1949.00
IUUC-Ont-072308 Oreochromis niloticus 66.29 0.00e+00 1368.00
IUUC-Oan-072723 Ornithorhynchus anatinus 65.65 0.00e+00 1605.00
IUUC-Ocu-073938 Oryctolagus cuniculus 90.23 0.00e+00 2471.00
IUUC-Ola-086375 Oryzias latipes 68.07 0.00e+00 1354.00
IUUC-Oga-088297 Otolemur garnettii 90.73 0.00e+00 2330.00
IUUC-Oar-089675 Ovis aries 89.38 0.00e+00 1734.00
IUUC-Ptr-091621 Pan troglodytes 94.16 0.00e+00 1994.00
IUUC-Pan-092118 Papio anubis 90.93 0.00e+00 2579.00
IUUC-Pfo-097246 Poecilia formosa 59.28 0.00e+00 1427.00
IUUC-Pab-098551 Pongo abelii 93.58 0.00e+00 1972.00
IUUC-Pca-100158 Procavia capensis 86.79 0.00e+00 2229.00
IUUC-Pva-103160 Pteropus vampyrus 91.99 0.00e+00 2313.00
IUUC-Rno-105355 Rattus norvegicus 88.66 0.00e+00 2290.00
IUUC-Sha-107057 Sarcophilus harrisii 73.13 0.00e+00 1941.00
IUUC-Sar-113011 Sorex araneus 90.73 0.00e+00 1514.00
IUUC-Ssc-115761 Sus scrofa 93.54 0.00e+00 2568.00
IUUC-Tgu-116956 Taeniopygia guttata 63.10 0.00e+00 794.00
IUUC-Tru-118739 Takifugu rubripes 65.63 0.00e+00 1362.00
IUUC-Tsy-118827 Tarsius syrichta 83.66 0.00e+00 1253.00
IUUC-Tni-119921 Tetraodon nigroviridis 61.22 0.00e+00 1397.00
IUUC-Tbe-128017 Tupaia belangeri 91.28 0.00e+00 1913.00
IUUC-Ttr-128869 Tursiops truncatus 92.19 0.00e+00 2315.00
IUUC-Vpa-130427 Vicugna pacos 97.01 0.00e+00 937.00
IUUC-Xtr-132734 Xenopus tropicalis 62.04 0.00e+00 1631.00
Created Date 25-Jun-2017

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