iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048732

Ensembl Protein ID

ENSSTOP00000000757.2

UniProt Accession

I3LXG0; I3LXG0_ICTTR

Genbank Protein ID

ENSSTOP00000000757

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01065570

Gene Name

BCL6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000000843.2	ENSSTOT00000000845.2	ENSSTOP00000000757.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	3.10e-14	53.1	32	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.dvqpevfrallkFlYtgklden 68
           +Dv++vv +e+f+ahk vL+a+S  Fy+ f+ +l+ +   + ++++ ++ pe f  ll+F+Yt++l++ 
   Q: 32   TDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCN--LSVINLDpEINPEGFCILLDFMYTSRLNLR 98
           7**********************************76..699999988*****************9875 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MASPADSCIQ FTRHASDVLL NLNRLRSRDI LTDVVIVVSR EQFRAHKTVL MACSGLFYSI 60
FTDQLKCNLS VINLDPEINP EGFCILLDFM YTSRLNLREG NIMAVMATAM YLQMEHVVDT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTTAGAACT GGGGTTCTTA GAAGTGGTGA TGCAAGAAGT TTCTAGGAAA GGCCGGACAC 60
CAGGTGATTA TTGCTGTTGC CGCCGCCGTT GCCGCTGGTG CCGCTGCCGC CGCCGCTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0005654--C:nucleoplasm
GO:0005657--C:replication fork
GO:0031490--F:chromatin DNA binding
GO:0001161--F:intronic transcription regulatory region sequence-specific DNA binding
GO:0046872--F:metal ion binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227--F:transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0030036--P:actin cytoskeleton organization
GO:0030183--P:B cell differentiation
GO:0000902--P:cell morphogenesis
GO:0006974--P:cellular response to DNA damage stimulus
GO:0048821--P:erythrocyte development
GO:0002467--P:germinal center formation
GO:0043066--P:negative regulation of apoptotic process
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0001953--P:negative regulation of cell-matrix adhesion
GO:2000773--P:negative regulation of cellular senescence
GO:0048294--P:negative regulation of isotype switching to IgE isotypes
GO:0032764--P:negative regulation of mast cell cytokine production
GO:0045746--P:negative regulation of Notch signaling pathway
GO:0035024--P:negative regulation of Rho protein signal transduction
GO:0045629--P:negative regulation of T-helper 2 cell differentiation
GO:0043065--P:positive regulation of apoptotic process
GO:0030890--P:positive regulation of B cell proliferation
GO:0051272--P:positive regulation of cellular component movement
GO:0031065--P:positive regulation of histone deacetylation
GO:0045666--P:positive regulation of neuron differentiation
GO:0000060--P:protein import into nucleus, translocation
GO:0043087--P:regulation of GTPase activity
GO:0050727--P:regulation of inflammatory response
GO:0043380--P:regulation of memory T cell differentiation
GO:0007266--P:Rho protein signal transduction
GO:0007283--P:spermatogenesis
GO:0042092--P:type 2 immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001625	Ailuropoda melanoleuca	91.38	0.00e+00	1286.00
IUUC-Atr-002779	Amborella trichopoda	34.44	8.00e-06	45.10
IUUC-Apl-003263	Anas platyrhynchos	74.72	0.00e+00	1060.00
IUUC-Ame-010714	Astyanax mexicanus	56.18	0.00e+00	733.00
IUUC-Bta-012576	Bos taurus	91.37	0.00e+00	1263.00
IUUC-Cja-018906	Callithrix jacchus	92.08	0.00e+00	1306.00
IUUC-Cfa-021058	Canis familiaris	89.77	0.00e+00	1258.00
IUUC-Cpo-022328	Cavia porcellus	92.08	0.00e+00	1310.00
IUUC-Csa-023942	Chlorocebus sabaeus	92.37	0.00e+00	1313.00
IUUC-Cho-024599	Choloepus hoffmanni	85.23	0.00e+00	705.00
IUUC-Dre-027605	Danio rerio	56.98	0.00e+00	753.00
IUUC-Dno-029476	Dasypus novemcinctus	84.91	0.00e+00	1217.00
IUUC-Dor-030724	Dipodomys ordii	90.95	0.00e+00	1264.00
IUUC-Ete-032678	Echinops telfairi	88.26	0.00e+00	1217.00
IUUC-Eca-034377	Equus caballus	92.22	0.00e+00	1295.00
IUUC-Eeu-034532	Erinaceus europaeus	92.72	0.00e+00	858.00
IUUC-Fca-036465	Felis catus	92.08	0.00e+00	1295.00
IUUC-Fal-036977	Ficedula albicollis	75.35	0.00e+00	1085.00
IUUC-Gmo-039515	Gadus morhua	69.01	8.00e-91	327.00
IUUC-Gga-040505	Gallus gallus	75.42	0.00e+00	1071.00
IUUC-Gac-041393	Gasterosteus aculeatus	55.66	0.00e+00	724.00
IUUC-Gma-043945	Glycine max	32.58	5.00e-05	42.70
IUUC-Ggo-044500	Gorilla gorilla	92.23	0.00e+00	1315.00
IUUC-Hsa-046648	Homo sapiens	92.22	0.00e+00	1314.00
IUUC-Lch-050387	Latimeria chalumnae	56.75	0.00e+00	712.00
IUUC-Loc-052103	Lepisosteus oculatus	58.70	0.00e+00	788.00
IUUC-Laf-053636	Loxodonta africana	91.24	0.00e+00	1305.00
IUUC-Mcc-055290	Macaca mulatta	92.36	0.00e+00	1314.00
IUUC-Meu-055910	Macropus eugenii	76.69	0.00e+00	1097.00
IUUC-Mga-059925	Meleagris gallopavo	75.00	0.00e+00	1058.00
IUUC-Mmr-060855	Microcebus murinus	92.22	0.00e+00	1296.00
IUUC-Mmu-063292	Mus musculus	90.96	0.00e+00	1260.00
IUUC-Mpu-066598	Mustela putorius furo	91.09	0.00e+00	1259.00
IUUC-Mlu-067370	Myotis lucifugus	89.99	0.00e+00	1253.00
IUUC-Nle-069870	Nomascus leucogenys	92.50	0.00e+00	1314.00
IUUC-Opr-070986	Ochotona princeps	88.54	0.00e+00	1222.00
IUUC-Ont-072475	Oreochromis niloticus	55.99	0.00e+00	692.00
IUUC-Oan-073596	Ornithorhynchus anatinus	81.21	0.00e+00	1123.00
IUUC-Ocu-073970	Oryctolagus cuniculus	91.11	0.00e+00	1306.00
IUUC-Ola-087102	Oryzias latipes	55.68	0.00e+00	732.00
IUUC-Oga-088873	Otolemur garnettii	91.24	0.00e+00	1299.00
IUUC-Oar-090083	Ovis aries	89.61	0.00e+00	1234.00
IUUC-Ptr-090628	Pan troglodytes	92.50	0.00e+00	1317.00
IUUC-Pan-092324	Papio anubis	84.22	0.00e+00	1220.00
IUUC-Psi-093695	Pelodiscus sinensis	76.83	0.00e+00	1049.00
IUUC-Pfo-096460	Poecilia formosa	54.43	0.00e+00	711.00
IUUC-Pab-098012	Pongo abelii	92.50	0.00e+00	1316.00
IUUC-Pca-100127	Procavia capensis	89.39	0.00e+00	1175.00
IUUC-Pva-102830	Pteropus vampyrus	82.45	0.00e+00	1179.00
IUUC-Rno-105752	Rattus norvegicus	91.10	0.00e+00	1260.00
IUUC-Sha-107259	Sarcophilus harrisii	79.41	0.00e+00	1123.00
IUUC-Sar-113610	Sorex araneus	92.28	0.00e+00	1065.00
IUUC-Ssc-115327	Sus scrofa	91.23	0.00e+00	1284.00
IUUC-Tgu-116457	Taeniopygia guttata	75.98	0.00e+00	1094.00
IUUC-Tru-118520	Takifugu rubripes	55.28	0.00e+00	719.00
IUUC-Tni-119969	Tetraodon nigroviridis	56.05	0.00e+00	712.00
IUUC-Tbe-127327	Tupaia belangeri	83.67	0.00e+00	1206.00
IUUC-Ttr-129204	Tursiops truncatus	89.39	0.00e+00	1234.00
IUUC-Xtr-132937	Xenopus tropicalis	63.37	0.00e+00	830.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence