iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118362

UUCD1 version

UUC-TaR-00102

Ensembl Protein ID

ENSTRUP00000023449.1

UniProt Accession

H2TFK3; H2TFK3_TAKRU

Protein Name

Uncharacterized protein

Gene Name

rnf144b

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000009323.1	ENSTRUT00000023546.1	ENSTRUP00000023449.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	5.90e-43	147.7	28	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+e++++ +  l++C+++fC +Cl+qy++l+i eg  + i+cp+++c+++  l +sei++ lv+e +++ y++l +e+ v+ d++ 
   Q: 28   CKLCLCEQPTTATRELQSCNCVFCVACLRQYVQLAIMEGGGAPITCPDMACQKSgvLLDSEIAS-LVSEGQVELYQRLSFERGVKLDPSK 116
           ***************************************************9988799******.69999******************** PP
   S: 89   kwcpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
            wcp  +C++v+ l++++  +   v+c++c+ +fC+ C+ +w +g  C+e +  ++ ++    ++  +  ++  +k+Cp C +yie+n+g
   Q: 117  AWCPVLECQAVCSLQPSTegQPGAVPCTTCRAVFCSACRGAWLDGHACSEQQPMMSPSH---GRSRPHDDADLPIKQCPVCGIYIERNQG 203
           ***************98866778899************************999988888...789999999******************* PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m C++Ck++fCw+C
   Q: 204  CAQMLCKSCKHTFCWYC 220
           ***************** PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MADKSATQSQ EDGDSAAEIS EVGWEVFCKL CLCEQPTTAT RELQSCNCVF CVACLRQYVQ 60
LAIMEGGGAP ITCPDMACQK SGVLLDSEIA SLVSEGQVEL YQRLSFERGV KLDPSKAWCP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGCGCACAC GCAGGCCAGA CAGGGCATGA GGCAGCAGTT TTGACCCCCT ACTTTGACGC 60
TAAGCAACCG CTTTTGTGCC AGGCAGGCGG CGGTGGATCT CCGGCGTGAA CAGCTGATCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1

Pfam

PF01485--IBR

SMART

SM00647--IBR

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0000151--C:ubiquitin ligase complex
GO:0046872--F:metal ion binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

tru:101079511

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001257	Ailuropoda melanoleuca	64.66	1.00e-100	359.00
IUUC-Apl-004112	Anas platyrhynchos	59.71	4.00e-89	320.00
IUUC-Aca-004533	Anolis carolinensis	60.29	3.00e-98	351.00
IUUC-Bta-012641	Bos taurus	64.29	3.00e-100	358.00
IUUC-Cja-019626	Callithrix jacchus	58.65	4.00e-86	310.00
IUUC-Cfa-020702	Canis familiaris	64.66	2.00e-100	358.00
IUUC-Cpo-022147	Cavia porcellus	63.53	2.00e-99	355.00
IUUC-Csa-023473	Chlorocebus sabaeus	65.04	2.00e-102	365.00
IUUC-Cho-024298	Choloepus hoffmanni	63.04	3.00e-84	304.00
IUUC-Dre-028099	Danio rerio	70.24	9.00e-107	379.00
IUUC-Dno-029122	Dasypus novemcinctus	60.30	3.00e-91	328.00
IUUC-Dor-030669	Dipodomys ordii	65.92	3.00e-86	310.00
IUUC-Ete-033141	Echinops telfairi	53.38	2.00e-70	259.00
IUUC-Eca-034360	Equus caballus	65.04	2.00e-101	362.00
IUUC-Eeu-034538	Erinaceus europaeus	53.20	8.00e-57	213.00
IUUC-Fca-036055	Felis catus	63.53	4.00e-99	353.00
IUUC-Fal-037339	Ficedula albicollis	60.46	6.00e-92	330.00
IUUC-Gmo-038780	Gadus morhua	73.56	1.00e-108	385.00
IUUC-Gga-040256	Gallus gallus	58.84	2.00e-92	331.00
IUUC-Gac-042127	Gasterosteus aculeatus	76.09	1.00e-119	422.00
IUUC-Ggo-044867	Gorilla gorilla	65.04	3.00e-102	364.00
IUUC-Hsa-046928	Homo sapiens	65.04	3.00e-102	364.00
IUUC-Hvu-047484	Hordeum vulgare	28.77	6.00e-17	82.00
IUUC-Itr-048250	Ictidomys tridecemlineatus	67.58	4.00e-72	263.00
IUUC-Lch-050168	Latimeria chalumnae	60.62	6.00e-100	357.00
IUUC-Lpe-051649	Leersia perrieri	28.85	2.00e-15	78.20
IUUC-Loc-052150	Lepisosteus oculatus	65.58	3.00e-95	341.00
IUUC-Laf-053967	Loxodonta africana	63.53	8.00e-100	356.00
IUUC-Mcc-055898	Macaca mulatta	65.04	2.00e-102	365.00
IUUC-Meu-056628	Macropus eugenii	89.04	3.00e-38	151.00
IUUC-Mga-059820	Meleagris gallopavo	58.48	7.00e-92	330.00
IUUC-Mmr-060680	Microcebus murinus	65.41	2.00e-102	365.00
IUUC-Mdo-062839	Monodelphis domestica	62.55	1.00e-98	352.00
IUUC-Mmu-063339	Mus musculus	63.91	2.00e-91	328.00
IUUC-Mpu-065973	Mustela putorius furo	64.29	4.00e-101	360.00
IUUC-Mlu-067112	Myotis lucifugus	63.81	3.00e-96	344.00
IUUC-Nle-069795	Nomascus leucogenys	65.04	2.00e-102	365.00
IUUC-Opr-070390	Ochotona princeps	60.53	6.00e-87	313.00
IUUC-Ont-072329	Oreochromis niloticus	80.00	3.00e-125	441.00
IUUC-Oan-072980	Ornithorhynchus anatinus	64.66	2.00e-100	358.00
IUUC-Ocu-073845	Oryctolagus cuniculus	64.66	5.00e-101	360.00
IUUC-Ola-086872	Oryzias latipes	79.04	3.00e-110	390.00
IUUC-Oga-088954	Otolemur garnettii	64.66	3.00e-101	361.00
IUUC-Oar-089879	Ovis aries	64.29	3.00e-100	357.00
IUUC-Ptr-090685	Pan troglodytes	65.04	3.00e-102	364.00
IUUC-Pan-092086	Papio anubis	65.04	2.00e-102	365.00
IUUC-Psi-093481	Pelodiscus sinensis	60.85	6.00e-94	337.00
IUUC-Pfo-096065	Poecilia formosa	74.92	5.00e-116	410.00
IUUC-Pab-098031	Pongo abelii	65.04	4.00e-102	364.00
IUUC-Pca-100936	Procavia capensis	64.66	6.00e-102	363.00
IUUC-Pva-102864	Pteropus vampyrus	56.02	5.00e-83	300.00
IUUC-Rno-105503	Rattus norvegicus	63.91	2.00e-91	328.00
IUUC-Sha-107425	Sarcophilus harrisii	64.42	6.00e-102	363.00
IUUC-Ssc-115458	Sus scrofa	64.96	6.00e-96	343.00
IUUC-Tgu-117226	Taeniopygia guttata	60.46	7.00e-93	333.00
IUUC-Tsy-119255	Tarsius syrichta	65.04	1.00e-101	362.00
IUUC-Tni-120140	Tetraodon nigroviridis	85.07	7.00e-121	426.00
IUUC-Tae-124420	Triticum aestivum	28.30	3.00e-17	83.20
IUUC-Tbe-127306	Tupaia belangeri	65.41	1.00e-101	362.00
IUUC-Ttr-128923	Tursiops truncatus	64.96	5.00e-95	340.00
IUUC-Vpa-130148	Vicugna pacos	64.29	4.00e-100	357.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence