iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001649

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01012154

Gene Name

TRIM38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000015923.1	ENSAMET00000017502.1	ENSAMEP00000016811.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.10e-09	38.2	11	83
E3 activity/RING/RING	2.30e-06	28.1	16	63

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk........tcPvtrqplteedlvPnltlrrliqa 67
            ee  C+I l lM++Pv +++G++y + +I+ +l++ g         +cP +r+p++  +l Pn+ l +li+a
   Q: 11   KEEATCAICLFLMTEPVSISCGHSYCKLCIRNFLENLGPaetqsnvfSCPQCRAPFQLASLRPNKQLGSLIEA 83
           68899*****************************66666688889**********************999987 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw...pglknssskefrCPlCr 46
           CaiCl  + + p++ +CgH +++ C+ ++    g+   +s+ f+CP Cr
   Q: 16   CAICLFLMTE-PVSISCGHSYCKLCIRNFlenLGPAETQSNVFSCPQCR 63
           ****888877.**************9777777577778**********8 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

KAMASATKKM KEEATCAICL FLMTEPVSIS CGHSYCKLCI RNFLENLGPA ETQSNVFSCP 60
QCRAPFQLAS LRPNKQLGSL IEAIKEMEHE MSCEEHGERL HLFCEDESQL ICWRCERSPR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAGCCATGG CCTCAGCCAC CAAGAAGATG AAGGAGGAAG CCACGTGTGC CATCTGCCTG 60
TTCCTAATGA CTGAGCCTGT GAGCATCAGC TGTGGACACA GCTACTGCAA ACTCTGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0004871--F:signal transducer activity
GO:0008270--F:zinc ion binding
GO:0050687--P:negative regulation of defense response to virus
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0046598--P:positive regulation of viral entry into host cell
GO:0045070--P:positive regulation of viral genome replication
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0032648--P:regulation of interferon-beta production

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007781	Ashbya gossypii	39.08	3.00e-10	59.30
IUUC-Bta-012574	Bos taurus	78.26	0.00e+00	747.00
IUUC-Cja-019759	Callithrix jacchus	73.49	0.00e+00	672.00
IUUC-Cfa-020431	Canis familiaris	84.48	0.00e+00	802.00
IUUC-Cpo-022541	Cavia porcellus	63.11	2.00e-176	611.00
IUUC-Csa-023320	Chlorocebus sabaeus	72.41	0.00e+00	709.00
IUUC-Cho-024964	Choloepus hoffmanni	70.12	2.00e-126	444.00
IUUC-Dno-029741	Dasypus novemcinctus	66.45	0.00e+00	626.00
IUUC-Dor-030298	Dipodomys ordii	60.88	2.00e-98	351.00
IUUC-Ete-032493	Echinops telfairi	62.37	6.00e-172	597.00
IUUC-Eca-033962	Equus caballus	77.37	0.00e+00	734.00
IUUC-Eeu-035228	Erinaceus europaeus	68.29	1.00e-130	459.00
IUUC-Fca-036349	Felis catus	80.43	0.00e+00	778.00
IUUC-Ggo-044493	Gorilla gorilla	73.88	0.00e+00	722.00
IUUC-Hsa-046161	Homo sapiens	72.84	0.00e+00	715.00
IUUC-Itr-048162	Ictidomys tridecemlineatus	61.56	9.00e-151	526.00
IUUC-Laf-054150	Loxodonta africana	74.09	0.00e+00	694.00
IUUC-Mcc-055076	Macaca mulatta	72.41	0.00e+00	708.00
IUUC-Mmu-063517	Mus musculus	53.56	2.00e-143	501.00
IUUC-Mpu-065752	Mustela putorius furo	89.46	0.00e+00	865.00
IUUC-Mlu-067758	Myotis lucifugus	59.71	4.00e-151	528.00
IUUC-Nle-069117	Nomascus leucogenys	73.65	0.00e+00	720.00
IUUC-Opr-071144	Ochotona princeps	65.52	1.00e-178	619.00
IUUC-Ocu-074825	Oryctolagus cuniculus	69.05	0.00e+00	674.00
IUUC-Oga-088744	Otolemur garnettii	70.30	6.00e-123	433.00
IUUC-Oar-089951	Ovis aries	77.83	0.00e+00	743.00
IUUC-Ptr-090519	Pan troglodytes	73.06	0.00e+00	716.00
IUUC-Pan-092059	Papio anubis	72.81	0.00e+00	712.00
IUUC-Pab-098747	Pongo abelii	73.92	0.00e+00	725.00
IUUC-Pca-100294	Procavia capensis	69.03	0.00e+00	664.00
IUUC-Pva-102129	Pteropus vampyrus	65.73	0.00e+00	646.00
IUUC-Sha-106630	Sarcophilus harrisii	40.00	6.00e-92	331.00
IUUC-Sar-113760	Sorex araneus	63.71	1.00e-161	562.00
IUUC-Tsy-119422	Tarsius syrichta	68.97	0.00e+00	652.00
IUUC-Tbe-127628	Tupaia belangeri	58.62	1.00e-93	335.00
IUUC-Ttr-129039	Tursiops truncatus	78.45	0.00e+00	759.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence