iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073980

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02068107

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000014141.3	ENSOCUT00000014141.3	ENSOCUP00000012153.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.90e-08	33.7	27	87
E3 activity/RING/RING	3.80e-08	33.8	29	70

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 6    flCpIslelMrdPvvlpsGitydrssIekwlasggk..tcPvtrqplteedlvPnltlrrl 64
             C++ le  +dPv++++G+ + +++I +w ++ ++   cPv+r++ + ++l Pn  l ++
   Q: 27   ASCSVCLEYLKDPVIIECGHNFCKACITRWWEDLERdfPCPVCRKTSRYRSLRPNRQLGSM 87
           68*****************************88887799****************998666 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle +kd p++  CgH f++ C+ +w        + f CP+Cr
   Q: 29   CSVCLEYLKD-PVIIECGHNFCKACITRW---WEDLERDFPCPVCR 70
           **********.999************999...666889999****8 PP

Organism

Oryctolagus cuniculus

Functional Description
(View)

Involved in the presentation of foreign antigens to the immune system.

Protein Sequence
(Fasta)

MAETSLLEAG TSAASTAAAL ENLQVEASCS VCLEYLKDPV IIECGHNFCK ACITRWWEDL 60
ERDFPCPVCR KTSRYRSLRP NRQLGSMVEI AKQLQAVKRK IRDESLCPQH HEALSLFCYE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCCGGGCGC AACTCGGCTG CGTCCTAGCG GCCAGCATCC CACCTCCACG CCACACCTCT 60
TCCTCACCTG GACACGCGTC CCTCCCTGCC ACGCCGACCA CGACGTCTCC TCTCCGCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0391--Immunity
KW-0472--Membrane
KW-0479--Metal-binding
KW-0490--MHC I
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR007110--Ig-like_dom
IPR013783--Ig-like_fold
IPR003006--Ig/MHC_CS
IPR003597--Ig_C1-set
IPR011161--MHC_I-like_Ag-recog
IPR011162--MHC_I/II-like_Ag-recog
IPR001039--MHC_I_a_a1/a2
IPR010579--MHC_I_a_C
IPR006574--PRY
IPR007175--Rpr2
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50835--IG_LIKE
PS00290--IG_MHC
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF07654--C1-set
PF00129--MHC_I
PF06623--MHC_I_C
PF13765--PRY
PF04032--Rpr2
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF
PR01638--MHCCLASSI

SMART

SM00336--BBOX
SM00407--IGc1
SM00589--PRY
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005622--C:intracellular
GO:0042612--C:MHC class I protein complex
GO:0008270--F:zinc ion binding
GO:0002474--P:antigen processing and presentation of peptide antigen via MHC class I
GO:0006955--P:immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001603	Ailuropoda melanoleuca	97.30	0.00e+00	701.00
IUUC-Aca-005381	Anolis carolinensis	66.49	1.00e-129	456.00
IUUC-Bta-012554	Bos taurus	97.14	0.00e+00	766.00
IUUC-Cja-019323	Callithrix jacchus	97.71	0.00e+00	676.00
IUUC-Cfa-020342	Canis familiaris	97.71	0.00e+00	698.00
IUUC-Cpo-022084	Cavia porcellus	94.79	0.00e+00	735.00
IUUC-Csa-023186	Chlorocebus sabaeus	97.99	0.00e+00	700.00
IUUC-Cho-024697	Choloepus hoffmanni	81.91	2.00e-175	608.00
IUUC-Dor-031021	Dipodomys ordii	86.22	1.00e-144	506.00
IUUC-Ete-032947	Echinops telfairi	91.29	4.00e-129	454.00
IUUC-Eca-033687	Equus caballus	97.14	0.00e+00	731.00
IUUC-Eeu-034957	Erinaceus europaeus	87.20	8.00e-85	307.00
IUUC-Fca-035406	Felis catus	97.42	0.00e+00	696.00
IUUC-Ggo-044526	Gorilla gorilla	90.24	0.00e+00	682.00
IUUC-Hsa-045987	Homo sapiens	97.34	0.00e+00	905.00
IUUC-Itr-048404	Ictidomys tridecemlineatus	94.96	0.00e+00	686.00
IUUC-Laf-054295	Loxodonta africana	96.30	0.00e+00	692.00
IUUC-Mcc-055765	Macaca mulatta	91.94	0.00e+00	686.00
IUUC-Meu-055997	Macropus eugenii	55.53	2.00e-77	282.00
IUUC-Mmr-061030	Microcebus murinus	93.80	0.00e+00	857.00
IUUC-Mdo-062936	Monodelphis domestica	85.71	1.00e-172	598.00
IUUC-Mmu-063767	Mus musculus	95.13	0.00e+00	680.00
IUUC-Mpu-066160	Mustela putorius furo	97.30	0.00e+00	700.00
IUUC-Mlu-068126	Myotis lucifugus	89.22	0.00e+00	723.00
IUUC-Nle-070041	Nomascus leucogenys	78.79	0.00e+00	822.00
IUUC-Opr-070394	Ochotona princeps	90.16	0.00e+00	679.00
IUUC-Oga-088422	Otolemur garnettii	90.54	0.00e+00	653.00
IUUC-Oar-089277	Ovis aries	89.97	2.00e-178	618.00
IUUC-Ptr-090853	Pan troglodytes	90.24	0.00e+00	682.00
IUUC-Pan-091993	Papio anubis	97.99	0.00e+00	700.00
IUUC-Psi-092975	Pelodiscus sinensis	70.03	3.00e-125	441.00
IUUC-Pab-097944	Pongo abelii	97.99	0.00e+00	700.00
IUUC-Pca-100795	Procavia capensis	81.45	3.00e-100	358.00
IUUC-Pva-103180	Pteropus vampyrus	88.71	0.00e+00	666.00
IUUC-Pgr-103696	Puccinia graminis	43.75	8.00e-07	47.00
IUUC-Rno-105736	Rattus norvegicus	92.72	0.00e+00	671.00
IUUC-Sar-113371	Sorex araneus	84.35	7.00e-139	486.00
IUUC-Ssc-116025	Sus scrofa	97.71	0.00e+00	699.00
IUUC-Tsy-119072	Tarsius syrichta	77.42	1.00e-100	358.00
IUUC-Tbe-127820	Tupaia belangeri	88.18	3.00e-141	494.00
IUUC-Ttr-128310	Tursiops truncatus	98.82	6.00e-98	351.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence