iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000021555.8	ENSDART00000029649.7	ENSDARP00000033749.8
ENSDARG00000021555.8	ENSDART00000157437.1	ENSDARP00000141580.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_PIM	8.10e-18	65.1	1	72

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvk 72
           m ++v++++++ f++e+++  +v+elKe++ + +gv+ +q+++I+aG++L +++tL+ +++ ++s+vh+v+ 
   Q: 1    MIVFVRFNSSHGFPVELEQGASVSELKEAVGRLQGVQSDQLRVIFAGRELCNESTLQGCDLPEQSTVHVVLP 72
           89*****99999*********************************************************975 PP

Organism

Danio rerio

Functional Description
(View)

Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

Protein Sequence
(Fasta)

MIVFVRFNSS HGFPVELEQG ASVSELKEAV GRLQGVQSDQ LRVIFAGREL CNESTLQGCD 60
LPEQSTVHVV LPPSTSAHRS ELIQQRRLGS GMESLTRLDL SSSRQTTASE GLAVILETEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACTGAGCGA GCACGCGACA TGTCAACAAA CACCAAAGTC ACACAGAGCG AATCTGCGAC 60
TTAACAGATG ACAGCATGAT CGGTAAGACT TTACTTATTT TCAGCAACTC GCTGCTGTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR003977--Parkin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF01485--IBR
PF00240--ubiquitin

PRINTS

PR01475--PARKIN

SMART

SM00647--IBR
SM00213--UBQ

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0046872--F:metal ion binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006120--P:mitochondrial electron transport, NADH to ubiquinone
GO:0051865--P:protein autoubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0006979--P:response to oxidative stress
GO:0009266--P:response to temperature stimulus

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001814	Ailuropoda melanoleuca	56.79	4.00e-91	327.00
IUUC-Apl-003304	Anas platyrhynchos	72.34	6.00e-148	516.00
IUUC-Aca-004908	Anolis carolinensis	63.89	6.00e-42	162.00
IUUC-Ame-011856	Astyanax mexicanus	80.96	0.00e+00	768.00
IUUC-Bta-013014	Bos taurus	61.74	5.00e-137	481.00
IUUC-Cel-018687	Caenorhabditis elegans	28.38	2.00e-44	173.00
IUUC-Cja-019274	Callithrix jacchus	57.29	6.00e-91	327.00
IUUC-Cfa-020461	Canis familiaris	56.25	4.00e-89	321.00
IUUC-Cpo-022251	Cavia porcellus	57.73	5.00e-93	333.00
IUUC-Csa-023112	Chlorocebus sabaeus	56.94	2.00e-86	312.00
IUUC-Cho-024504	Choloepus hoffmanni	45.38	1.00e-102	367.00
IUUC-Dno-028946	Dasypus novemcinctus	76.32	3.00e-34	136.00
IUUC-Dor-030508	Dipodomys ordii	52.50	2.00e-95	342.00
IUUC-Dme-031980	Drosophila melanogaster	44.23	3.00e-111	395.00
IUUC-Ete-032281	Echinops telfairi	49.14	2.00e-59	223.00
IUUC-Eca-033228	Equus caballus	57.44	2.00e-91	328.00
IUUC-Fal-037507	Ficedula albicollis	65.44	0.00e+00	626.00
IUUC-Gmo-038744	Gadus morhua	62.72	2.00e-98	352.00
IUUC-Gga-040353	Gallus gallus	66.16	0.00e+00	636.00
IUUC-Gac-042519	Gasterosteus aculeatus	56.17	1.00e-149	522.00
IUUC-Hsa-046016	Homo sapiens	62.02	1.00e-163	569.00
IUUC-Itr-048744	Ictidomys tridecemlineatus	61.47	1.00e-155	543.00
IUUC-Loc-052389	Lepisosteus oculatus	68.60	1.00e-180	626.00
IUUC-Mcc-054933	Macaca mulatta	61.80	1.00e-163	569.00
IUUC-Meu-055963	Macropus eugenii	51.83	2.00e-106	379.00
IUUC-Mpo-057509	Magnaporthe poae	37.33	3.00e-10	59.30
IUUC-Mga-059626	Meleagris gallopavo	73.68	1.00e-28	117.00
IUUC-Mmr-061566	Microcebus murinus	69.23	7.00e-76	276.00
IUUC-Mdo-061952	Monodelphis domestica	75.34	1.00e-25	107.00
IUUC-Mmu-063561	Mus musculus	62.15	2.00e-171	595.00
IUUC-Mpu-065799	Mustela putorius furo	57.29	2.00e-90	325.00
IUUC-Mlu-068134	Myotis lucifugus	58.06	2.00e-110	392.00
IUUC-Nle-070078	Nomascus leucogenys	56.19	2.00e-93	335.00
IUUC-Opr-070541	Ochotona princeps	61.85	5.00e-154	537.00
IUUC-Ont-071743	Oreochromis niloticus	60.39	1.00e-158	553.00
IUUC-Oan-073700	Ornithorhynchus anatinus	66.67	9.00e-17	77.80
IUUC-Ola-086426	Oryzias latipes	64.57	2.00e-64	237.00
IUUC-Oga-088867	Otolemur garnettii	61.85	4.00e-159	554.00
IUUC-Oar-089365	Ovis aries	59.23	1.00e-120	426.00
IUUC-Ptr-091371	Pan troglodytes	62.02	1.00e-162	566.00
IUUC-Pan-092443	Papio anubis	56.60	2.00e-89	322.00
IUUC-Psi-093851	Pelodiscus sinensis	55.70	2.00e-75	275.00
IUUC-Pfo-097194	Poecilia formosa	58.30	3.00e-146	511.00
IUUC-Pab-097999	Pongo abelii	49.86	7.00e-88	317.00
IUUC-Pca-100410	Procavia capensis	61.77	1.00e-134	473.00
IUUC-Pva-102300	Pteropus vampyrus	56.71	2.00e-138	486.00
IUUC-Rno-105556	Rattus norvegicus	57.09	9.00e-91	326.00
IUUC-Sha-106992	Sarcophilus harrisii	64.81	2.00e-16	77.00
IUUC-Ssl-108406	Sclerotinia sclerotiorum	50.00	5.00e-08	52.80
IUUC-Sar-113121	Sorex araneus	75.21	5.00e-48	184.00
IUUC-Ssc-116435	Sus scrofa	57.49	4.00e-92	331.00
IUUC-Tgu-117489	Taeniopygia guttata	65.52	0.00e+00	627.00
IUUC-Tru-117927	Takifugu rubripes	60.00	4.00e-164	571.00
IUUC-Tsy-119372	Tarsius syrichta	66.16	1.00e-127	450.00
IUUC-Tni-120043	Tetraodon nigroviridis	60.25	2.00e-146	512.00
IUUC-Tbe-127539	Tupaia belangeri	53.65	3.00e-130	458.00
IUUC-Ttr-129149	Tursiops truncatus	59.23	2.00e-161	561.00
IUUC-Vpa-130439	Vicugna pacos	46.02	2.00e-109	389.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence