iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096171

Ensembl Protein ID

ENSPFOP00000012443.1

UniProt Accession

A0A087Y340; A0A087Y340_POEFO

Genbank Protein ID

ENSPFOP00000012443

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01008004

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000012457.1	ENSPFOT00000012460.1	ENSPFOP00000012443.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.60e-134	449.2	624	956

Active Site

Position(s)	Description	Evidence
925	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dl++rl+v f+gEegld+gG++re+++lls+e+ np+++lf+y  +++++lq+np+s + np+hl++F f+Gr++++al++g+++d+
   Q: 624  PYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKSNYCLQINPASAI-NPDHLSYFCFIGRFIAMALFHGKFIDT 711
           6799*******************************************************98.89************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
            +s +fyk++l+kkl l+dle++dpe+y+sl +i++n   +iee+gl++ fsv+ eilg++++++Lkp+G ni Vt+eNkeeY++l++e
   Q: 712  GFSLPFYKRMLNKKLILKDLESIDPEFYNSLIWIRDN---NIEECGLEMYFSVDMEILGKISSHDLKPDGTNILVTEENKEEYISLMAE 797
           ***********************************99...9************************************************ PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +r+ +g++ q++af +Gfnev+pl++l++F+e+ele+++cG++e+d++d++++t y++ yt++s++i+wFw+ ++e+++e r +++qFv
   Q: 798  WRFSRGVEGQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLQDWQRNTVYRH-YTRNSKQIIWFWQLVKEVDNEVRLRLMQFV 885
           ********************************************************99.****************************** PP
   S: 269  TgssrlPlgGfaelk....prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           Tg++rlPlgGfael+    p++f+i+k ++d++lP+s+TCfn+L+LP+Y+s+e+lkekLl+Aieet+gF++
   Q: 886  TGTCRLPLGGFAELMgsngPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQ 956
           *********************************************************************96 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MATASSRAET SHNHRRTSQL HAIVSCAKLK RKKSVFGAAI YVEVTAEGET RRTAKSHSSS 60
NPKWDERLTL TVTPHTQVDF KVWSHHTLKA DALLGKATLD LIQALERHDR KLENVKEVLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACCTTTGCT TTGAGGCAAT AACAGTGTAA CCGCTCAGAC CTCAAACTTA TTTAAAAATA 60
ACTACAATAT AAAAACCCAT TAAATTACTT ACGTATAATA AAACATGAAG TAAAGTATTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001213	Ailuropoda melanoleuca	70.65	0.00e+00	1325.00
IUUC-Apl-003310	Anas platyrhynchos	93.65	0.00e+00	1154.00
IUUC-Aca-005388	Anolis carolinensis	70.06	0.00e+00	1293.00
IUUC-Ago-007742	Ashbya gossypii	47.19	6.00e-159	554.00
IUUC-Bgr-012148	Blumeria graminis	45.03	4.00e-147	515.00
IUUC-Bta-012857	Bos taurus	71.47	0.00e+00	1325.00
IUUC-Cel-018299	Caenorhabditis elegans	67.70	0.00e+00	845.00
IUUC-Cja-019448	Callithrix jacchus	71.78	0.00e+00	1345.00
IUUC-Cfa-020728	Canis familiaris	71.50	0.00e+00	1340.00
IUUC-Cpo-021635	Cavia porcellus	89.78	0.00e+00	1131.00
IUUC-Csa-023805	Chlorocebus sabaeus	92.66	0.00e+00	1129.00
IUUC-Cin-025212	Ciona intestinalis	73.58	0.00e+00	913.00
IUUC-Csv-026256	Ciona savignyi	72.66	0.00e+00	906.00
IUUC-Dre-028245	Danio rerio	70.50	0.00e+00	1249.00
IUUC-Dno-029618	Dasypus novemcinctus	70.71	0.00e+00	1325.00
IUUC-Dme-032041	Drosophila melanogaster	71.00	0.00e+00	902.00
IUUC-Ete-032779	Echinops telfairi	89.61	0.00e+00	1062.00
IUUC-Eca-033313	Equus caballus	91.53	0.00e+00	1130.00
IUUC-Eeu-035259	Erinaceus europaeus	64.12	0.00e+00	1152.00
IUUC-Fca-035420	Felis catus	70.93	0.00e+00	1337.00
IUUC-Fal-037335	Ficedula albicollis	71.59	0.00e+00	1360.00
IUUC-Gmo-039172	Gadus morhua	90.48	0.00e+00	1095.00
IUUC-Ggr-040107	Gaeumannomyces graminis	46.73	8.00e-152	531.00
IUUC-Gga-040246	Gallus gallus	72.03	0.00e+00	1344.00
IUUC-Gac-042211	Gasterosteus aculeatus	98.12	0.00e+00	1236.00
IUUC-Ggo-045001	Gorilla gorilla	71.28	0.00e+00	1186.00
IUUC-Hsa-046544	Homo sapiens	70.96	0.00e+00	1335.00
IUUC-Itr-048860	Ictidomys tridecemlineatus	71.40	0.00e+00	1316.00
IUUC-Lch-050398	Latimeria chalumnae	92.49	0.00e+00	1168.00
IUUC-Loc-052116	Lepisosteus oculatus	96.11	0.00e+00	1214.00
IUUC-Laf-053551	Loxodonta africana	71.03	0.00e+00	1327.00
IUUC-Mga-059986	Meleagris gallopavo	72.00	0.00e+00	1351.00
IUUC-Mmr-060945	Microcebus murinus	68.93	0.00e+00	1272.00
IUUC-Mdo-063024	Monodelphis domestica	90.18	0.00e+00	1083.00
IUUC-Mmu-063202	Mus musculus	91.82	0.00e+00	1134.00
IUUC-Mpu-065773	Mustela putorius furo	71.81	0.00e+00	1332.00
IUUC-Nle-069188	Nomascus leucogenys	71.30	0.00e+00	1343.00
IUUC-Ont-072226	Oreochromis niloticus	86.17	0.00e+00	1632.00
IUUC-Oan-073497	Ornithorhynchus anatinus	94.52	0.00e+00	1155.00
IUUC-Ocu-073891	Oryctolagus cuniculus	62.35	0.00e+00	1132.00
IUUC-Ola-087438	Oryzias latipes	97.63	0.00e+00	1245.00
IUUC-Oga-087922	Otolemur garnettii	92.32	0.00e+00	1137.00
IUUC-Oar-089317	Ovis aries	70.91	0.00e+00	1307.00
IUUC-Ptr-090484	Pan troglodytes	70.85	0.00e+00	1335.00
IUUC-Pan-092117	Papio anubis	71.40	0.00e+00	1335.00
IUUC-Psi-093338	Pelodiscus sinensis	72.34	0.00e+00	1367.00
IUUC-Pma-094279	Petromyzon marinus	73.17	0.00e+00	840.00
IUUC-Pab-098654	Pongo abelii	90.07	0.00e+00	1091.00
IUUC-Pva-102811	Pteropus vampyrus	67.43	0.00e+00	1210.00
IUUC-Rno-106125	Rattus norvegicus	70.20	0.00e+00	1312.00
IUUC-Sha-107243	Sarcophilus harrisii	90.26	0.00e+00	1137.00
IUUC-Ssc-115368	Sus scrofa	71.01	0.00e+00	1315.00
IUUC-Tgu-117079	Taeniopygia guttata	72.03	0.00e+00	1348.00
IUUC-Tru-118062	Takifugu rubripes	77.29	0.00e+00	1471.00
IUUC-Tsy-119507	Tarsius syrichta	66.63	0.00e+00	1210.00
IUUC-Tni-120151	Tetraodon nigroviridis	97.28	0.00e+00	1221.00
IUUC-Xtr-132877	Xenopus tropicalis	64.99	0.00e+00	1134.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence