iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000002699.5	ENSGALT00000004255.4	ENSGALP00000004246.3
ENSGALG00000002699.5	ENSGALT00000061155.1	ENSGALP00000044431.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.70e-18	66.0	784	835

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 8    vlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           + y++ a +  eL+l++Gdvv++ +    d+gW+kg  e++g+ G fP+ +ve+
   Q: 784  ARYNFAARDMRELSLREGDVVKIYSRIGGDQGWWKG--ETNGRVGWFPSTYVEE 835
           67**********************************..9*************86 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MEEWRQCGRW LIDCKVLPPN HRVVWPSAVV FDLAQTLRDG VLLCQLLNNL APGSIDLKDI 60
NFRPQMSQFL CLKNIRTFLK VCHDKFGLRN SDLFDPFDLF DVRDFGKVIS AVSRLSFHSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TACGGCGGCA GTCCGAGCCG TGCTGCGTGC AGGTGGGGCC CCGCAACTTT CCTGGGGCAG 60
TGCCTGCGGG GGGGGACGCA ACTTACGCGG CGGCAGCTCC TTTGTCCGCG GGGCGATGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR022613--CAMSAP_CH
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF11971--CAMSAP_CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0016477--P:cell migration
GO:0030032--P:lamellipodium assembly
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:0030193--P:regulation of blood coagulation
GO:0008361--P:regulation of cell size
GO:0010468--P:regulation of gene expression
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001437	Ailuropoda melanoleuca	85.13	0.00e+00	1379.00
IUUC-Apl-003262	Anas platyrhynchos	94.35	0.00e+00	1597.00
IUUC-Aca-004628	Anolis carolinensis	68.92	0.00e+00	944.00
IUUC-Ath-007352	Arabidopsis thaliana	34.92	3.00e-03	37.00
IUUC-Ame-011608	Astyanax mexicanus	82.69	0.00e+00	1444.00
IUUC-Bta-013147	Bos taurus	85.95	0.00e+00	1229.00
IUUC-Cja-018877	Callithrix jacchus	84.55	0.00e+00	1306.00
IUUC-Cfa-020315	Canis familiaris	90.24	0.00e+00	1208.00
IUUC-Cpo-021543	Cavia porcellus	84.97	0.00e+00	1233.00
IUUC-Csa-024204	Chlorocebus sabaeus	85.38	0.00e+00	1493.00
IUUC-Cin-025115	Ciona intestinalis	37.40	1.00e-148	520.00
IUUC-Csv-025995	Ciona savignyi	37.08	2.00e-151	530.00
IUUC-Dre-028308	Danio rerio	79.71	0.00e+00	1399.00
IUUC-Dno-029584	Dasypus novemcinctus	87.23	0.00e+00	1120.00
IUUC-Dor-031014	Dipodomys ordii	78.38	0.00e+00	1174.00
IUUC-Eca-033448	Equus caballus	84.17	0.00e+00	1461.00
IUUC-Eeu-035182	Erinaceus europaeus	80.30	0.00e+00	649.00
IUUC-Fca-035460	Felis catus	87.04	0.00e+00	1275.00
IUUC-Fal-036684	Ficedula albicollis	91.93	0.00e+00	1587.00
IUUC-Gmo-038816	Gadus morhua	78.98	0.00e+00	1127.00
IUUC-Gac-041353	Gasterosteus aculeatus	80.51	0.00e+00	1182.00
IUUC-Ggo-044558	Gorilla gorilla	87.02	0.00e+00	1498.00
IUUC-Hsa-046208	Homo sapiens	87.13	0.00e+00	1501.00
IUUC-Itr-047931	Ictidomys tridecemlineatus	85.08	0.00e+00	1145.00
IUUC-Loc-052827	Lepisosteus oculatus	77.98	0.00e+00	1405.00
IUUC-Laf-054009	Loxodonta africana	83.18	0.00e+00	1442.00
IUUC-Mcc-055054	Macaca mulatta	87.13	0.00e+00	1501.00
IUUC-Mga-060106	Meleagris gallopavo	96.08	0.00e+00	1623.00
IUUC-Mmr-061118	Microcebus murinus	86.64	0.00e+00	1500.00
IUUC-Mdo-062380	Monodelphis domestica	91.38	0.00e+00	1298.00
IUUC-Mmu-063135	Mus musculus	88.36	0.00e+00	1539.00
IUUC-Mpu-066135	Mustela putorius furo	88.72	0.00e+00	1400.00
IUUC-Nle-069465	Nomascus leucogenys	80.53	0.00e+00	1367.00
IUUC-Ont-071945	Oreochromis niloticus	78.68	0.00e+00	1366.00
IUUC-Oan-073384	Ornithorhynchus anatinus	83.96	0.00e+00	1159.00
IUUC-Ola-087499	Oryzias latipes	79.71	0.00e+00	1102.00
IUUC-Oga-088444	Otolemur garnettii	90.32	0.00e+00	1268.00
IUUC-Oar-089576	Ovis aries	83.36	0.00e+00	1165.00
IUUC-Ptr-090507	Pan troglodytes	88.13	0.00e+00	1507.00
IUUC-Pan-092325	Papio anubis	91.78	0.00e+00	1532.00
IUUC-Psi-094021	Pelodiscus sinensis	94.99	0.00e+00	1571.00
IUUC-Pma-094372	Petromyzon marinus	53.15	0.00e+00	696.00
IUUC-Pfo-096732	Poecilia formosa	78.91	0.00e+00	1383.00
IUUC-Pab-098426	Pongo abelii	76.83	0.00e+00	1119.00
IUUC-Pca-100295	Procavia capensis	86.00	0.00e+00	1388.00
IUUC-Rno-105332	Rattus norvegicus	87.90	0.00e+00	1481.00
IUUC-Sha-106529	Sarcophilus harrisii	87.84	0.00e+00	1203.00
IUUC-Ssc-116176	Sus scrofa	85.27	0.00e+00	1350.00
IUUC-Tgu-116917	Taeniopygia guttata	93.51	0.00e+00	1449.00
IUUC-Tru-118398	Takifugu rubripes	76.24	0.00e+00	956.00
IUUC-Tni-120819	Tetraodon nigroviridis	77.42	0.00e+00	1171.00
IUUC-Xtr-132747	Xenopus tropicalis	81.87	0.00e+00	1384.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence