iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.00e-16	59.5	181	247
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.90e-06	26.2	280	310

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv+l+ g  +++ah++vL+a S++F a+f+++  e + +++v++++v+p +++ l+++ Ytg l++ 
   Q: 181  CDVLLIAGPLKIPAHRLVLSAVSDYFAAMFTNDVLEAR-QEEVKMEGVDPNALNSLVQYAYTGVLQLR 247
           8************************************9.*************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclgi++f+d+ +c +L  +a++++  hF
   Q: 280  PSNCLGIRSFGDAQGCMELQNVAHKYTMEHF 310
           89************************98777 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSVSGKKEFD VKQILRLRWR WFSHPSQGSP NTGSCLQQEG YEHRGTPVQG RLKNHSRDRN 60
GLKKSNSPVH HDILTPVPGP APTHQRVLQN WHQQNVIVHL QANEDTPKAV PEGNLLKEAC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCTGGCTT CAGCTAAGCT GGAAGTATTC ACAGGCAGAG GGGGAGGGGA GAGAAAGCAA 60
GAAAAACTGC TCGCTCTCTC AGCACTTGTG CTTTTGTTAG TTCTACACAA GAGGCAGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005815--C:microtubule organizing center
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001422	Ailuropoda melanoleuca	85.98	0.00e+00	1219.00
IUUC-Apl-004156	Anas platyrhynchos	83.66	0.00e+00	961.00
IUUC-Aca-004238	Anolis carolinensis	76.99	0.00e+00	1095.00
IUUC-Ame-011287	Astyanax mexicanus	68.16	0.00e+00	878.00
IUUC-Bta-013232	Bos taurus	84.27	0.00e+00	1084.00
IUUC-Cja-018916	Callithrix jacchus	87.12	0.00e+00	1236.00
IUUC-Cfa-020972	Canis familiaris	87.18	0.00e+00	1013.00
IUUC-Csa-023849	Chlorocebus sabaeus	88.28	0.00e+00	1284.00
IUUC-Dor-030708	Dipodomys ordii	82.38	0.00e+00	1170.00
IUUC-Ete-033156	Echinops telfairi	77.91	0.00e+00	776.00
IUUC-Eca-033542	Equus caballus	87.17	0.00e+00	1244.00
IUUC-Fal-036999	Ficedula albicollis	78.13	0.00e+00	1139.00
IUUC-Gga-040215	Gallus gallus	79.00	0.00e+00	1159.00
IUUC-Ggo-045074	Gorilla gorilla	88.42	0.00e+00	1287.00
IUUC-Hsa-046486	Homo sapiens	88.16	0.00e+00	1257.00
IUUC-Loc-052015	Lepisosteus oculatus	75.80	0.00e+00	1052.00
IUUC-Laf-053627	Loxodonta africana	86.61	0.00e+00	1256.00
IUUC-Mcc-055418	Macaca mulatta	88.42	0.00e+00	1290.00
IUUC-Meu-056859	Macropus eugenii	71.98	2.00e-144	506.00
IUUC-Mga-059582	Meleagris gallopavo	78.56	0.00e+00	1092.00
IUUC-Mmr-061648	Microcebus murinus	88.98	0.00e+00	1303.00
IUUC-Mdo-062785	Monodelphis domestica	83.13	0.00e+00	932.00
IUUC-Mmu-063807	Mus musculus	96.09	0.00e+00	1411.00
IUUC-Mpu-066279	Mustela putorius furo	86.31	0.00e+00	1005.00
IUUC-Mlu-067981	Myotis lucifugus	85.22	0.00e+00	1248.00
IUUC-Ncr-068856	Neurospora crassa	37.74	2.00e-04	39.70
IUUC-Nle-070033	Nomascus leucogenys	88.13	0.00e+00	1253.00
IUUC-Ont-071932	Oreochromis niloticus	72.09	0.00e+00	1039.00
IUUC-Ocu-073854	Oryctolagus cuniculus	87.69	0.00e+00	1028.00
IUUC-Oin-079973	Oryza indica	30.95	9.00e-34	138.00
IUUC-Ola-087436	Oryzias latipes	71.49	0.00e+00	1010.00
IUUC-Oar-089952	Ovis aries	86.19	0.00e+00	1250.00
IUUC-Ptr-091649	Pan troglodytes	82.15	0.00e+00	1132.00
IUUC-Pan-091798	Papio anubis	88.56	0.00e+00	1290.00
IUUC-Psi-093728	Pelodiscus sinensis	78.16	0.00e+00	1142.00
IUUC-Pfo-096954	Poecilia formosa	72.12	0.00e+00	1025.00
IUUC-Pab-098461	Pongo abelii	88.15	0.00e+00	1273.00
IUUC-Pva-102458	Pteropus vampyrus	86.58	0.00e+00	1132.00
IUUC-Sha-107322	Sarcophilus harrisii	82.42	0.00e+00	953.00
IUUC-Ssc-116001	Sus scrofa	89.22	0.00e+00	1299.00
IUUC-Tgu-116994	Taeniopygia guttata	78.97	0.00e+00	1152.00
IUUC-Tni-120794	Tetraodon nigroviridis	69.92	0.00e+00	960.00
IUUC-Tbe-128118	Tupaia belangeri	72.23	0.00e+00	917.00
IUUC-Ttr-129220	Tursiops truncatus	80.97	0.00e+00	1144.00
IUUC-Vpa-130811	Vicugna pacos	83.45	0.00e+00	1177.00
IUUC-Xtr-132358	Xenopus tropicalis	76.38	0.00e+00	1117.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence