iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-054780

Ensembl Protein ID

ENSMMUP00000020763.3

UniProt Accession

F7ANQ0; F7ANQ0_MACMU

Genbank Protein ID

ENSMMUP00000020763

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03000004

Gene Name

KLHL17

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000015802.3	ENSMMUT00000022193.3	ENSMMUP00000020763.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.80e-21	76.3	93	157
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	4.50e-13	48.2	192	222

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           +D++l+v+ +e++ahk+vLa++S++F+a+f++e++es+ +  v+++d++p+++ +l++F Yt ++ 
   Q: 93   CDIVLHVAAKEIRAHKVVLASCSPYFHAMFTNEMSESR-QTHVTLHDIDPQALDQLVQFAYTAEIV 157
           8*************************************.***********************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclgi+ fAd+++c+dL +aa++++l+hF
   Q: 192  PSNCLGIRGFADAHSCSDLLKAAHRYVLQHF 222
           89***************************** PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MQPRSERPAG RTQSPEHGSP GPGPEAPPPP PPPQPPAPEA ERTRPRQARP AAPMEGAVQL 60
LSREGHSVAH NSKRHYHDAF VAMSRMRQRG LLCDIVLHVA AKEIRAHKVV LASCSPYFHA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGCCCC GCAGCGAGCG CCCGGCCGGC AGGACGCAGA GCCCGGAGCA CGGCAGCCCG 60
GGGCCTGGGC CCGAGGCGCC GCCGCCGCCG CCACCGCCGC AGCCGCCGGC GTGAGTGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0032839--C:dendrite cytoplasm
GO:0005615--C:extracellular space
GO:0051015--F:actin filament binding
GO:0030036--P:actin cytoskeleton organization
GO:0007420--P:brain development
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002095	Ailuropoda melanoleuca	71.36	0.00e+00	800.00
IUUC-Apl-003315	Anas platyrhynchos	71.94	0.00e+00	801.00
IUUC-Aca-005317	Anolis carolinensis	65.96	0.00e+00	764.00
IUUC-Ame-010707	Astyanax mexicanus	65.73	0.00e+00	757.00
IUUC-Bta-012531	Bos taurus	72.91	0.00e+00	823.00
IUUC-Bra-017070	Brassica rapa	30.85	3.00e-17	83.20
IUUC-Cfa-021138	Canis familiaris	73.36	0.00e+00	827.00
IUUC-Cpo-021432	Cavia porcellus	68.65	0.00e+00	844.00
IUUC-Csa-023772	Chlorocebus sabaeus	87.91	0.00e+00	967.00
IUUC-Dre-028401	Danio rerio	65.73	0.00e+00	757.00
IUUC-Dno-029729	Dasypus novemcinctus	69.70	0.00e+00	772.00
IUUC-Dor-030659	Dipodomys ordii	71.19	0.00e+00	796.00
IUUC-Ete-033128	Echinops telfairi	60.24	6.00e-149	520.00
IUUC-Eca-033856	Equus caballus	70.70	0.00e+00	779.00
IUUC-Eeu-034646	Erinaceus europaeus	66.72	0.00e+00	711.00
IUUC-Fca-036183	Felis catus	70.86	0.00e+00	793.00
IUUC-Fal-037046	Ficedula albicollis	66.89	0.00e+00	743.00
IUUC-Gmo-039526	Gadus morhua	59.38	0.00e+00	662.00
IUUC-Gga-040510	Gallus gallus	66.83	0.00e+00	764.00
IUUC-Gac-042529	Gasterosteus aculeatus	57.69	0.00e+00	640.00
IUUC-Ggo-044992	Gorilla gorilla	71.23	0.00e+00	857.00
IUUC-Hsa-046621	Homo sapiens	71.23	0.00e+00	857.00
IUUC-Itr-048791	Ictidomys tridecemlineatus	71.39	0.00e+00	822.00
IUUC-Lch-049449	Latimeria chalumnae	65.89	0.00e+00	757.00
IUUC-Loc-052690	Lepisosteus oculatus	62.77	0.00e+00	742.00
IUUC-Laf-053925	Loxodonta africana	54.62	9.00e-104	370.00
IUUC-Meu-056812	Macropus eugenii	95.82	0.00e+00	724.00
IUUC-Mpo-057526	Magnaporthe poae	28.95	3.00e-07	48.50
IUUC-Mga-059704	Meleagris gallopavo	66.45	0.00e+00	763.00
IUUC-Mmr-061724	Microcebus murinus	71.69	0.00e+00	801.00
IUUC-Mmu-063886	Mus musculus	71.69	0.00e+00	817.00
IUUC-Mpu-066774	Mustela putorius furo	71.36	0.00e+00	800.00
IUUC-Nle-070159	Nomascus leucogenys	70.93	0.00e+00	854.00
IUUC-Opr-070367	Ochotona princeps	86.24	0.00e+00	763.00
IUUC-Ont-071757	Oreochromis niloticus	65.40	0.00e+00	750.00
IUUC-Ocu-074674	Oryctolagus cuniculus	63.77	0.00e+00	688.00
IUUC-Ola-086760	Oryzias latipes	64.56	0.00e+00	756.00
IUUC-Oga-088570	Otolemur garnettii	71.99	0.00e+00	824.00
IUUC-Oar-090344	Ovis aries	67.07	0.00e+00	770.00
IUUC-Ptr-090946	Pan troglodytes	71.08	0.00e+00	856.00
IUUC-Pan-092661	Papio anubis	87.91	0.00e+00	967.00
IUUC-Psi-094009	Pelodiscus sinensis	63.90	0.00e+00	729.00
IUUC-Pfo-097164	Poecilia formosa	75.34	0.00e+00	866.00
IUUC-Pab-097554	Pongo abelii	72.71	0.00e+00	766.00
IUUC-Pca-100460	Procavia capensis	75.46	0.00e+00	812.00
IUUC-Pva-102180	Pteropus vampyrus	70.47	0.00e+00	815.00
IUUC-Rno-105907	Rattus norvegicus	71.69	0.00e+00	817.00
IUUC-Smo-109299	Selaginella moellendorffii	27.16	5.00e-16	79.70
IUUC-Sar-113112	Sorex araneus	97.52	1.00e-150	526.00
IUUC-Ssc-115448	Sus scrofa	90.20	0.00e+00	830.00
IUUC-Tgu-117293	Taeniopygia guttata	66.89	0.00e+00	763.00
IUUC-Tru-117814	Takifugu rubripes	64.03	0.00e+00	735.00
IUUC-Tni-120531	Tetraodon nigroviridis	65.23	0.00e+00	750.00
IUUC-Tbe-127460	Tupaia belangeri	70.12	0.00e+00	748.00
IUUC-Xtr-132356	Xenopus tropicalis	66.39	0.00e+00	756.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence