iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037461

Ensembl Protein ID

ENSFALP00000006520.1

UniProt Accession

U3JUR6; U3JUR6_FICAL

Genbank Protein ID

ENSFALP00000006520

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AGTO01020493

Gene Name

YES1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000006245.1	ENSFALT00000006549.1	ENSFALP00000006520.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.70e-15	56.4	94	149

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydyea ++d+L++kkG+  ++i  ++++++W+++ + ++gk G +P+n+v+ ++
   Q: 94   FVALYDYEARTTDDLSFKKGERFQII--NNTEGDWWEARSIATGKTGYIPSNYVAPAD 149
           789***********************..8999**********************9875 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MGCIKSKEGK GPAMKYRTEN APEPVISHVS HYGSDSSQAT QSPSIKGSAV NFNSHSMTPF 60
GGPSGMTPFG GASSSFSAVP STYPSTLTGG VTVFVALYDY EARTTDDLSF KKGERFQIIN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAATAATTAG GGCTTCCCTG GTCTGGTAAT AGTTTAGATT TTATTCCAGA ACACTTTTTC 60
ATCAGAGTTT GCACTCTGCA TGGAGTTTAA CAGTAATAAA CTAGCATTTG GATTAACTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005884--C:actin filament
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0036120--P:cellular response to platelet-derived growth factor stimulus
GO:0071300--P:cellular response to retinoic acid
GO:0071560--P:cellular response to transforming growth factor beta stimulus
GO:0015758--P:glucose transport
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter

KEGG

fab:101820125

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002374	Ailuropoda melanoleuca	92.62	0.00e+00	1021.00
IUUC-Apl-004032	Anas platyrhynchos	98.89	0.00e+00	1091.00
IUUC-Aca-004255	Anolis carolinensis	94.45	0.00e+00	1077.00
IUUC-Ame-010954	Astyanax mexicanus	88.48	0.00e+00	1007.00
IUUC-Bta-013503	Bos taurus	91.50	0.00e+00	990.00
IUUC-Cel-018682	Caenorhabditis elegans	58.17	1.00e-150	526.00
IUUC-Cja-019694	Callithrix jacchus	91.90	0.00e+00	1002.00
IUUC-Cfa-020402	Canis familiaris	92.42	0.00e+00	1020.00
IUUC-Cpo-022506	Cavia porcellus	92.24	0.00e+00	1018.00
IUUC-Csa-023713	Chlorocebus sabaeus	92.63	0.00e+00	1011.00
IUUC-Cin-025390	Ciona intestinalis	72.23	0.00e+00	668.00
IUUC-Csv-026029	Ciona savignyi	63.86	0.00e+00	646.00
IUUC-Dre-027978	Danio rerio	86.08	0.00e+00	965.00
IUUC-Dno-029897	Dasypus novemcinctus	91.18	0.00e+00	910.00
IUUC-Dor-030202	Dipodomys ordii	95.80	0.00e+00	916.00
IUUC-Eca-034157	Equus caballus	91.87	0.00e+00	1014.00
IUUC-Eeu-034950	Erinaceus europaeus	88.35	4.00e-173	600.00
IUUC-Fca-036233	Felis catus	92.42	0.00e+00	1057.00
IUUC-Gmo-038929	Gadus morhua	83.97	0.00e+00	917.00
IUUC-Gga-041107	Gallus gallus	98.52	0.00e+00	1092.00
IUUC-Gac-042321	Gasterosteus aculeatus	85.06	0.00e+00	951.00
IUUC-Hsa-047010	Homo sapiens	92.27	0.00e+00	1017.00
IUUC-Lch-050239	Latimeria chalumnae	91.13	0.00e+00	1037.00
IUUC-Loc-052314	Lepisosteus oculatus	89.91	0.00e+00	970.00
IUUC-Laf-053517	Loxodonta africana	92.42	0.00e+00	999.00
IUUC-Mcc-055626	Macaca mulatta	92.63	0.00e+00	1012.00
IUUC-Mga-059310	Meleagris gallopavo	98.52	0.00e+00	1092.00
IUUC-Mmr-061652	Microcebus murinus	92.24	0.00e+00	1017.00
IUUC-Mdo-062963	Monodelphis domestica	91.31	0.00e+00	1027.00
IUUC-Mmu-064128	Mus musculus	91.50	0.00e+00	1026.00
IUUC-Mpu-065906	Mustela putorius furo	92.79	0.00e+00	1023.00
IUUC-Mlu-067035	Myotis lucifugus	92.83	0.00e+00	1022.00
IUUC-Nle-069041	Nomascus leucogenys	88.21	0.00e+00	957.00
IUUC-Opr-070299	Ochotona princeps	83.18	0.00e+00	890.00
IUUC-Ont-072337	Oreochromis niloticus	86.65	0.00e+00	973.00
IUUC-Oan-072997	Ornithorhynchus anatinus	98.25	0.00e+00	943.00
IUUC-Ocu-074171	Oryctolagus cuniculus	92.61	0.00e+00	1024.00
IUUC-Oba-075994	Oryza barthii	34.98	2.00e-21	97.40
IUUC-Ola-086619	Oryzias latipes	84.21	0.00e+00	972.00
IUUC-Oga-087957	Otolemur garnettii	92.05	0.00e+00	1008.00
IUUC-Oar-089670	Ovis aries	90.57	0.00e+00	1010.00
IUUC-Ptr-091352	Pan troglodytes	92.27	0.00e+00	1018.00
IUUC-Pan-092202	Papio anubis	92.63	0.00e+00	1012.00
IUUC-Psi-093310	Pelodiscus sinensis	96.86	0.00e+00	1100.00
IUUC-Pma-094232	Petromyzon marinus	86.23	0.00e+00	863.00
IUUC-Pfo-096137	Poecilia formosa	83.54	0.00e+00	957.00
IUUC-Pab-098301	Pongo abelii	96.29	0.00e+00	948.00
IUUC-Pva-102592	Pteropus vampyrus	88.17	0.00e+00	962.00
IUUC-Rno-105544	Rattus norvegicus	91.68	0.00e+00	1000.00
IUUC-Sar-113364	Sorex araneus	88.91	0.00e+00	949.00
IUUC-Tgu-117380	Taeniopygia guttata	100.00	0.00e+00	1132.00
IUUC-Tru-117594	Takifugu rubripes	85.33	0.00e+00	964.00
IUUC-Tni-120433	Tetraodon nigroviridis	84.45	0.00e+00	950.00
IUUC-Ttr-128893	Tursiops truncatus	92.05	0.00e+00	1014.00
IUUC-Vpa-130060	Vicugna pacos	92.61	0.00e+00	1013.00
IUUC-Xtr-132322	Xenopus tropicalis	92.79	0.00e+00	1045.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence