iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-054597

Ensembl Protein ID

ENSMMUP00000019658.2

UniProt Accession

F6VE69; F6VE69_MACMU

Genbank Protein ID

AFE77318.1; AFH31624.1; AFI36588.1

Protein Name

TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

Genbank Nucleotide ID

JSUE03031953; JU474820; JV046517

Gene Name

TAB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000014995.3	ENSMMUT00000021024.3	ENSMMUP00000019658.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	1.70e-14	54.1	665	692
UBD/Alpha-Helix/CUE	1.70e-07	32.2	11	50

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 2    eaqWaCsaCTflNePeavkCemCsrpRg 29
           +aqW+C+aCTflN+P++++Ce+C++pR+
   Q: 665  GAQWNCTACTFLNHPALIRCEQCEMPRH 692
           79*************************8 PP

UBD/Alpha-Helix/CUE

   S: 4    taleqLkeiFPnldysviqvvLeantgsleaavnnLLegs 43
           + l+ L++ FP++++ v+ +++++n+++l+a++  L ++s
   Q: 11   QVLHDLRQKFPEVPEVVVSRCMLQNNNNLDACCAVLSQES 50
           689**********************************998 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAQGSHQIDF QVLHDLRQKF PEVPEVVVSR CMLQNNNNLD ACCAVLSQES TRYLYGEGDL 60
NFSDDSGISG LRNHMTSLNL DLQSQNIYHH GREGSRMNGS RTLTHSISDG QLQGGQSNSE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCTCCAGAC CCAGTTCCTG GACCTGCCCT GGAAAAGAAG TATCCTGTAG AGATGAGCTC 60
ACTGCAGTTA CTTAATTAAC AATTTGTAAG CTGCAAAAAT GGCAATGGGC CAACCAAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR003892--CUE
IPR001876--Znf_RanBP2

PROSITE

PS51140--CUE
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF02845--CUE

SMART

SM00546--CUE
SM00547--ZnF_RBZ

Gene Ontology

GO:0005829--C:cytosol
GO:0016301--F:kinase activity
GO:0008270--F:zinc ion binding
GO:0007507--P:heart development
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045860--P:positive regulation of protein kinase activity

KEGG

mcc:696875

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001681	Ailuropoda melanoleuca	96.39	0.00e+00	1260.00
IUUC-Apl-004125	Anas platyrhynchos	73.81	0.00e+00	949.00
IUUC-Aca-005332	Anolis carolinensis	85.00	0.00e+00	1092.00
IUUC-Ame-010937	Astyanax mexicanus	68.82	6.00e-115	408.00
IUUC-Bta-012567	Bos taurus	96.68	0.00e+00	1261.00
IUUC-Cja-020008	Callithrix jacchus	99.13	0.00e+00	1245.00
IUUC-Cfa-020602	Canis familiaris	96.25	0.00e+00	1258.00
IUUC-Cpo-022483	Cavia porcellus	91.27	0.00e+00	1146.00
IUUC-Csa-024196	Chlorocebus sabaeus	99.86	0.00e+00	1276.00
IUUC-Cho-025022	Choloepus hoffmanni	89.52	2.00e-52	199.00
IUUC-Cin-025456	Ciona intestinalis	34.31	4.00e-26	112.00
IUUC-Dre-027773	Danio rerio	53.17	2.00e-151	529.00
IUUC-Dno-029801	Dasypus novemcinctus	92.93	0.00e+00	1223.00
IUUC-Dor-030605	Dipodomys ordii	95.82	0.00e+00	1264.00
IUUC-Ete-032438	Echinops telfairi	92.21	0.00e+00	1216.00
IUUC-Eca-033410	Equus caballus	96.39	0.00e+00	1266.00
IUUC-Eeu-034509	Erinaceus europaeus	92.64	0.00e+00	1219.00
IUUC-Fca-035548	Felis catus	96.39	0.00e+00	1226.00
IUUC-Fal-037250	Ficedula albicollis	86.96	0.00e+00	1127.00
IUUC-Gmo-039053	Gadus morhua	65.00	4.00e-47	179.00
IUUC-Gga-040871	Gallus gallus	86.96	0.00e+00	1116.00
IUUC-Gac-041832	Gasterosteus aculeatus	63.13	0.00e+00	711.00
IUUC-Ggo-044976	Gorilla gorilla	99.71	0.00e+00	1274.00
IUUC-Hsa-045963	Homo sapiens	99.71	0.00e+00	1274.00
IUUC-Itr-048861	Ictidomys tridecemlineatus	95.13	0.00e+00	914.00
IUUC-Lch-050144	Latimeria chalumnae	75.82	0.00e+00	964.00
IUUC-Loc-052931	Lepisosteus oculatus	64.28	0.00e+00	821.00
IUUC-Laf-053883	Loxodonta africana	95.96	0.00e+00	1251.00
IUUC-Meu-056202	Macropus eugenii	92.22	0.00e+00	808.00
IUUC-Mor-057018	Magnaporthe oryzae	64.00	2.00e-05	43.90
IUUC-Mla-059157	Melampsora laricipopulina	46.15	2.00e-03	36.20
IUUC-Mga-059601	Meleagris gallopavo	70.60	0.00e+00	873.00
IUUC-Mmr-061047	Microcebus murinus	97.40	0.00e+00	1270.00
IUUC-Mdo-061944	Monodelphis domestica	93.60	0.00e+00	1179.00
IUUC-Mmu-063095	Mus musculus	94.66	0.00e+00	1257.00
IUUC-Mpu-066232	Mustela putorius furo	96.10	0.00e+00	1259.00
IUUC-Mlu-067513	Myotis lucifugus	96.25	0.00e+00	1251.00
IUUC-Nle-069405	Nomascus leucogenys	99.57	0.00e+00	1272.00
IUUC-Opr-071184	Ochotona princeps	94.87	7.00e-121	427.00
IUUC-Ont-071678	Oreochromis niloticus	61.79	0.00e+00	685.00
IUUC-Oan-072975	Ornithorhynchus anatinus	78.50	8.00e-149	520.00
IUUC-Ocu-073763	Oryctolagus cuniculus	96.39	0.00e+00	1226.00
IUUC-Olo-080805	Oryza longistaminata	40.00	3.00e-03	35.40
IUUC-Opu-083275	Oryza punctata	42.86	3.80e-02	32.70
IUUC-Ola-087478	Oryzias latipes	55.72	0.00e+00	629.00
IUUC-Oga-088892	Otolemur garnettii	87.82	0.00e+00	1172.00
IUUC-Oar-089573	Ovis aries	97.11	0.00e+00	1265.00
IUUC-Ptr-091270	Pan troglodytes	99.71	0.00e+00	1274.00
IUUC-Pan-092250	Papio anubis	99.71	0.00e+00	1275.00
IUUC-Psi-093732	Pelodiscus sinensis	85.96	0.00e+00	1109.00
IUUC-Pma-094397	Petromyzon marinus	43.93	9.00e-31	127.00
IUUC-Pfo-097098	Poecilia formosa	60.64	0.00e+00	658.00
IUUC-Pab-098776	Pongo abelii	99.71	0.00e+00	1274.00
IUUC-Pca-100202	Procavia capensis	90.91	0.00e+00	1144.00
IUUC-Pva-103025	Pteropus vampyrus	96.54	0.00e+00	1234.00
IUUC-Rno-105366	Rattus norvegicus	93.80	0.00e+00	1253.00
IUUC-Sha-107249	Sarcophilus harrisii	92.36	0.00e+00	1197.00
IUUC-Stu-112401	Solanum tuberosum	33.80	8.00e-04	36.60
IUUC-Sar-113207	Sorex araneus	95.32	0.00e+00	924.00
IUUC-Ssc-116409	Sus scrofa	93.80	0.00e+00	1215.00
IUUC-Tgu-116911	Taeniopygia guttata	87.11	0.00e+00	1129.00
IUUC-Tru-118667	Takifugu rubripes	58.39	0.00e+00	647.00
IUUC-Tsy-119562	Tarsius syrichta	96.71	0.00e+00	716.00
IUUC-Tni-120195	Tetraodon nigroviridis	54.75	2.00e-174	605.00
IUUC-Tbe-127934	Tupaia belangeri	94.66	0.00e+00	1251.00
IUUC-Ttr-128519	Tursiops truncatus	94.89	0.00e+00	727.00
IUUC-Vpa-130279	Vicugna pacos	92.53	0.00e+00	1192.00
IUUC-Xtr-131844	Xenopus tropicalis	77.83	0.00e+00	991.00
IUUC-Xma-133854	Xiphophorus maculatus	60.17	0.00e+00	659.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence