iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088048

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03153723

Gene Name

EML2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000033974.1	ENSOGAT00000033248.1	ENSOGAP00000016677.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-13	50.3	672	708

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH++ +t l++ +d + +v+ s+D  i  WD+ t+++
   Q: 672  GHSSFITHLDWaQDsGCFVTNSGDYEILYWDPATCKQ 708
           8***********878****************998876 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAERGPAFCG LYDTSSLLQY CNDDNLSAAS GMEVDDRVSA LEQRLQLQED ELAVLKAALA 60
DALRRLRACE EQGAVLRARN TPKGRAPPRL GTTASVCQLL KGLPTRTPLN GLGAPRRVGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGC GCGGCCCGGC CTTCTGCGGC CTCTACGACA CGTCCTCTCT GCTGCAGTAC 60
TGCAACGGTG AGACCCTTCC TCAGTTCCGA CCTTGGCCCC GCCCAGGGAT GGACCCCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR000595--cNMP-bd_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50042--CNMP_BINDING_3
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0072686--C:mitotic spindle
GO:0031115--P:negative regulation of microtubule polymerization
GO:0010968--P:regulation of microtubule nucleation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002155	Ailuropoda melanoleuca	91.86	0.00e+00	1410.00
IUUC-Aca-005316	Anolis carolinensis	72.18	0.00e+00	1092.00
IUUC-Bta-013267	Bos taurus	92.55	0.00e+00	1460.00
IUUC-Cja-019146	Callithrix jacchus	87.93	0.00e+00	1177.00
IUUC-Cfa-020267	Canis familiaris	93.28	0.00e+00	1474.00
IUUC-Dno-028961	Dasypus novemcinctus	91.01	0.00e+00	1390.00
IUUC-Eca-033785	Equus caballus	91.31	0.00e+00	1425.00
IUUC-Eeu-035302	Erinaceus europaeus	94.84	0.00e+00	724.00
IUUC-Fca-036170	Felis catus	89.03	0.00e+00	1362.00
IUUC-Ggo-044669	Gorilla gorilla	89.55	0.00e+00	1368.00
IUUC-Hsa-046141	Homo sapiens	93.23	0.00e+00	1461.00
IUUC-Itr-048788	Ictidomys tridecemlineatus	91.59	0.00e+00	1442.00
IUUC-Laf-054137	Loxodonta africana	86.75	0.00e+00	1124.00
IUUC-Mcc-055780	Macaca mulatta	91.93	0.00e+00	1139.00
IUUC-Meu-056664	Macropus eugenii	80.62	0.00e+00	1063.00
IUUC-Mmr-060853	Microcebus murinus	93.23	0.00e+00	1454.00
IUUC-Mdo-062224	Monodelphis domestica	82.43	0.00e+00	1123.00
IUUC-Mmu-063860	Mus musculus	91.99	0.00e+00	1438.00
IUUC-Mpu-066043	Mustela putorius furo	92.73	0.00e+00	1443.00
IUUC-Mlu-067125	Myotis lucifugus	70.90	0.00e+00	982.00
IUUC-Nle-069618	Nomascus leucogenys	87.23	0.00e+00	1296.00
IUUC-Opr-070228	Ochotona princeps	81.71	0.00e+00	1060.00
IUUC-Ocu-074087	Oryctolagus cuniculus	81.50	0.00e+00	848.00
IUUC-Oar-089907	Ovis aries	91.41	0.00e+00	1177.00
IUUC-Pan-092082	Papio anubis	93.28	0.00e+00	1471.00
IUUC-Pab-097619	Pongo abelii	92.71	0.00e+00	1227.00
IUUC-Pca-101070	Procavia capensis	81.09	0.00e+00	1033.00
IUUC-Pva-102957	Pteropus vampyrus	86.80	0.00e+00	1129.00
IUUC-Rno-105074	Rattus norvegicus	90.22	0.00e+00	1174.00
IUUC-Sha-106692	Sarcophilus harrisii	80.19	0.00e+00	1180.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence