iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-15	57.7	251	308

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++++  +ly + +q++++L+++ Gd+++++  e+ +e+W+kg  + + + G+fP+nFv+++e
   Q: 251  QMNTYVALYRFIPQENEDLEMRPGDMITLL--EDSNEDWWKG--KIQDRVGFFPANFVQRVE 308
           678999************************..999*******..8***************98 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

QLQKLKRSLS FKTKSLRSKS ADNFFPRTNS DVKPQADLLA KASPGPSPIP IPGSPASMPT 60
KAGLHPGSNS KVHAFQEHVF KKPTFCDVCN HMIVGTHAKH GLRCGACKMS IHHKCADGLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCTCCAGA AACTAAAACG GTCACTTTCT TTCAAGACCA AGAGCTTGCG GAGCAAAAGT 60
GCCGACAACT TCTTCCCAAG GACCAACAGT GATGTGAAAC CACAAGCAGA CCTGCTGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR002219--PE/DAG-bd
IPR011511--SH3_2
IPR001452--SH3_domain
IPR013315--Spectrin_alpha_SH3

PROSITE

PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN
PR01887--SPECTRNALPHA

SMART

SM00109--C1
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0030315--C:T-tubule
GO:0046872--F:metal ion binding
GO:0034605--P:cellular response to heat
GO:0035556--P:intracellular signal transduction
GO:0006936--P:muscle contraction
GO:1901385--P:regulation of voltage-gated calcium channel activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002138	Ailuropoda melanoleuca	85.52	1.00e-179	622.00
IUUC-Apl-003909	Anas platyrhynchos	75.91	7.00e-155	540.00
IUUC-Aca-005108	Anolis carolinensis	72.81	2.00e-82	297.00
IUUC-Ame-011702	Astyanax mexicanus	56.80	8.00e-124	437.00
IUUC-Bta-013252	Bos taurus	87.74	0.00e+00	627.00
IUUC-Cja-018981	Callithrix jacchus	84.51	1.00e-175	609.00
IUUC-Cfa-020616	Canis familiaris	83.92	3.00e-170	591.00
IUUC-Cpo-021624	Cavia porcellus	84.20	4.00e-174	603.00
IUUC-Csa-023048	Chlorocebus sabaeus	83.42	1.00e-174	605.00
IUUC-Cho-024761	Choloepus hoffmanni	77.72	7.00e-163	566.00
IUUC-Dno-028867	Dasypus novemcinctus	83.42	8.00e-175	606.00
IUUC-Ete-033109	Echinops telfairi	83.11	4.00e-163	567.00
IUUC-Eca-033427	Equus caballus	86.92	1.00e-179	622.00
IUUC-Fca-036129	Felis catus	83.24	2.00e-174	605.00
IUUC-Fal-037364	Ficedula albicollis	75.07	2.00e-145	508.00
IUUC-Gga-040761	Gallus gallus	76.57	1.00e-161	562.00
IUUC-Gac-042076	Gasterosteus aculeatus	62.06	2.00e-122	432.00
IUUC-Ggo-044836	Gorilla gorilla	87.50	1.00e-141	495.00
IUUC-Hsa-046375	Homo sapiens	83.97	2.00e-175	607.00
IUUC-Itr-048358	Ictidomys tridecemlineatus	87.43	0.00e+00	632.00
IUUC-Lch-049737	Latimeria chalumnae	71.33	3.00e-106	377.00
IUUC-Loc-051865	Lepisosteus oculatus	68.45	1.00e-144	506.00
IUUC-Laf-053927	Loxodonta africana	84.47	5.00e-173	600.00
IUUC-Mcc-054821	Macaca mulatta	83.15	8.00e-173	599.00
IUUC-Mga-059635	Meleagris gallopavo	77.38	1.00e-147	515.00
IUUC-Mmr-061072	Microcebus murinus	86.14	3.00e-179	620.00
IUUC-Mmu-063555	Mus musculus	96.46	0.00e+00	667.00
IUUC-Mpu-066475	Mustela putorius furo	85.02	6.00e-149	520.00
IUUC-Mlu-068166	Myotis lucifugus	83.11	2.00e-175	607.00
IUUC-Nle-069985	Nomascus leucogenys	83.70	3.00e-174	604.00
IUUC-Opr-070930	Ochotona princeps	68.31	2.00e-127	449.00
IUUC-Ont-072501	Oreochromis niloticus	56.82	7.00e-118	417.00
IUUC-Oan-072818	Ornithorhynchus anatinus	78.83	7.00e-128	449.00
IUUC-Ocu-074488	Oryctolagus cuniculus	84.52	4.00e-157	546.00
IUUC-Ola-087078	Oryzias latipes	58.87	2.00e-116	412.00
IUUC-Oga-088176	Otolemur garnettii	84.86	8.00e-169	586.00
IUUC-Oar-090183	Ovis aries	86.92	0.00e+00	627.00
IUUC-Ptr-091139	Pan troglodytes	83.70	5.00e-175	606.00
IUUC-Pan-092571	Papio anubis	82.93	8.00e-172	596.00
IUUC-Psi-093399	Pelodiscus sinensis	77.53	4.00e-163	567.00
IUUC-Pma-094266	Petromyzon marinus	53.07	5.00e-106	377.00
IUUC-Pfo-096207	Poecilia formosa	60.26	9.00e-105	373.00
IUUC-Pab-097825	Pongo abelii	83.70	5.00e-175	607.00
IUUC-Pva-102481	Pteropus vampyrus	86.29	8.00e-144	503.00
IUUC-Sha-106561	Sarcophilus harrisii	68.94	9.00e-136	476.00
IUUC-Sar-113303	Sorex araneus	82.93	7.00e-153	533.00
IUUC-Ssc-116135	Sus scrofa	86.10	6.00e-179	619.00
IUUC-Tgu-116598	Taeniopygia guttata	76.36	2.00e-162	565.00
IUUC-Tsy-118889	Tarsius syrichta	84.51	5.00e-177	613.00
IUUC-Tni-120208	Tetraodon nigroviridis	59.42	3.00e-115	408.00
IUUC-Ttr-128655	Tursiops truncatus	76.29	2.00e-150	525.00
IUUC-Vpa-130814	Vicugna pacos	88.36	1.00e-77	283.00
IUUC-Xtr-132129	Xenopus tropicalis	60.28	1.00e-120	426.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence