iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021387

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02003471

Gene Name

RNF146

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000004785.3	ENSCPOT00000004836.2	ENSCPOP00000004306.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	90.53	3.00e-165	578.00	IUUC-Hsa-045790

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cavia porcellus

Protein Sequence
(Fasta)

RMAGCGEIDH SINMLPTNRK ANESCSNAAP SLTVPECAIC LQTCVHPVSL PCKHVFCYLC 60
VKGASWLGKR CALCRQEIPE DFLDKPTLLS PEELKAASRG NGEYAWYYEG RNGWWQYDER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGATGGCTG GCTGTGGCGA AATCGATCAC TCAATAAACA TGCTTCCTAC GAACAGGAAG 60
GCCAATGAGT CCTGTTCTAA TGCTGCACCT TCTCTGACAG TTCCGGAATG CGCCATTTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033509--RNF146
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50918--WWE
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02825--WWE

SMART

SM00184--RING
SM00678--WWE

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0072572--F:poly-ADP-D-ribose binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002237	Ailuropoda melanoleuca	88.89	7.00e-143	499.00
IUUC-Apl-004143	Anas platyrhynchos	76.69	6.00e-129	453.00
IUUC-Aca-004557	Anolis carolinensis	72.47	2.00e-125	442.00
IUUC-Ame-011088	Astyanax mexicanus	60.00	7.00e-82	297.00
IUUC-Bta-012639	Bos taurus	89.33	1.00e-143	502.00
IUUC-Cel-018462	Caenorhabditis elegans	28.35	5.00e-19	87.40
IUUC-Cja-019397	Callithrix jacchus	90.81	9.00e-147	512.00
IUUC-Cfa-021140	Canis familiaris	86.07	1.00e-150	525.00
IUUC-Csa-023503	Chlorocebus sabaeus	87.04	2.00e-143	501.00
IUUC-Cho-024895	Choloepus hoffmanni	85.86	7.00e-129	452.00
IUUC-Cin-025455	Ciona intestinalis	51.59	3.00e-43	167.00
IUUC-Dre-028824	Danio rerio	45.97	6.00e-81	294.00
IUUC-Dno-029269	Dasypus novemcinctus	88.61	3.00e-148	517.00
IUUC-Dor-030592	Dipodomys ordii	89.36	1.00e-156	545.00
IUUC-Dme-031618	Drosophila melanogaster	55.83	8.00e-56	211.00
IUUC-Ete-032478	Echinops telfairi	89.04	1.00e-155	542.00
IUUC-Eca-033389	Equus caballus	91.85	7.00e-169	586.00
IUUC-Fca-035488	Felis catus	91.04	8.00e-153	532.00
IUUC-Fal-037087	Ficedula albicollis	75.42	2.00e-143	501.00
IUUC-Gga-040401	Gallus gallus	82.91	2.00e-131	461.00
IUUC-Gac-042412	Gasterosteus aculeatus	63.53	5.00e-88	317.00
IUUC-Ggo-045417	Gorilla gorilla	90.99	2.00e-141	494.00
IUUC-Hsa-045790	Homo sapiens	90.53	4.00e-146	510.00
IUUC-Itr-048820	Ictidomys tridecemlineatus	92.39	3.00e-163	567.00
IUUC-Lch-049493	Latimeria chalumnae	70.11	1.00e-114	405.00
IUUC-Loc-052927	Lepisosteus oculatus	65.85	3.00e-100	358.00
IUUC-Laf-053904	Loxodonta africana	89.17	1.00e-150	525.00
IUUC-Mcc-055427	Macaca mulatta	86.39	7.00e-147	513.00
IUUC-Mmr-060580	Microcebus murinus	90.76	7.00e-148	516.00
IUUC-Mdo-062094	Monodelphis domestica	97.71	2.00e-78	283.00
IUUC-Mmu-063363	Mus musculus	89.08	1.00e-156	545.00
IUUC-Mpu-066816	Mustela putorius furo	89.17	3.00e-144	504.00
IUUC-Mlu-067433	Myotis lucifugus	88.61	4.00e-165	573.00
IUUC-Nle-068986	Nomascus leucogenys	89.97	5.00e-158	550.00
IUUC-Ont-072670	Oreochromis niloticus	64.89	2.00e-80	292.00
IUUC-Oan-073330	Ornithorhynchus anatinus	87.56	1.00e-107	382.00
IUUC-Ocu-074161	Oryctolagus cuniculus	89.55	2.00e-157	548.00
IUUC-Ola-086902	Oryzias latipes	69.37	5.00e-84	304.00
IUUC-Oga-089159	Otolemur garnettii	89.04	2.00e-167	581.00
IUUC-Oar-089586	Ovis aries	89.89	2.00e-139	488.00
IUUC-Ptr-090987	Pan troglodytes	90.53	4.00e-146	510.00
IUUC-Pan-091867	Papio anubis	86.43	2.00e-147	514.00
IUUC-Psi-094024	Pelodiscus sinensis	81.56	8.00e-134	469.00
IUUC-Pma-094453	Petromyzon marinus	63.91	3.00e-65	241.00
IUUC-Pfo-097108	Poecilia formosa	51.04	1.00e-84	306.00
IUUC-Pab-097997	Pongo abelii	88.86	7.00e-152	530.00
IUUC-Pca-100260	Procavia capensis	87.36	5.00e-153	533.00
IUUC-Pva-103140	Pteropus vampyrus	88.30	1.00e-150	526.00
IUUC-Rno-105795	Rattus norvegicus	87.29	2.00e-155	541.00
IUUC-Sha-107033	Sarcophilus harrisii	84.64	7.00e-147	513.00
IUUC-Ssc-116395	Sus scrofa	89.72	3.00e-165	574.00
IUUC-Tgu-116685	Taeniopygia guttata	87.21	2.00e-127	448.00
IUUC-Tru-118014	Takifugu rubripes	64.62	2.00e-84	304.00
IUUC-Tsy-119326	Tarsius syrichta	83.01	7.00e-159	553.00
IUUC-Tni-120322	Tetraodon nigroviridis	68.54	1.00e-81	296.00
IUUC-Tbe-128067	Tupaia belangeri	89.42	7.00e-156	543.00
IUUC-Ttr-128530	Tursiops truncatus	90.25	3.00e-151	527.00
IUUC-Vpa-130322	Vicugna pacos	90.81	2.00e-154	538.00
IUUC-Xtr-132606	Xenopus tropicalis	66.20	3.00e-115	408.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence