iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019566

UUCD1 version

UUC-CaJ-00389

Ensembl Protein ID

ENSCJAP00000039544.2

UniProt Accession

F7CUN4; F7CUN4_CALJA

Genbank Protein ID

JAB04547.1; JAB21721.1; JAB35311.1

Protein Name

E3 ubiquitin-protein ligase RNF149

Genbank Nucleotide ID

ACFV01148552; GAMS01001415; GAMQ01006540

Gene Name

RNF149

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000021239.2	ENSCJAT00000041777.2	ENSCJAP00000039544.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.50e-06	27.8	269	310

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C e f  kd  ++lpC+H+fh+ C+  w         + +CP C+
   Q: 269  CAVCIENFkvKDIIRILPCKHIFHRICIDPW------LLDHRTCPMCK 310
           ********8866699****************......9999******6 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MAWRGPDAGV GARSALALAL LVLALCPPGA RSRALEWFSA VVSTEYLDPQ TNMTVWSVSE 60
SGRFGDSSPK EGAQGLVGVP RAPGGDLEGC EPDTRFFVPA PGGRVSAPWV ALVARGGCTF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCTTCCTG GGCGGCAGTG TGCGTCCGCT TGTCTGCATT TCTCTGCTGC ACCGCACTAG 60
GGTGTGAGTT TGGCCCCTCC TAGTCAGCTC TGTGGAGCTA CCATGGCGTG GCGGGGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-0472--Membrane
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0016021--C:integral component of membrane
GO:0016874--F:ligase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0035690--P:cellular response to drug
GO:0043409--P:negative regulation of MAPK cascade
GO:0031647--P:regulation of protein stability

KEGG

cjc:100413729

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001968	Ailuropoda melanoleuca	83.29	8.00e-176	609.00
IUUC-Apl-004109	Anas platyrhynchos	69.66	2.00e-100	358.00
IUUC-Bta-012340	Bos taurus	81.82	5.00e-167	580.00
IUUC-Cfa-020289	Canis familiaris	83.19	1.00e-108	385.00
IUUC-Cpo-021916	Cavia porcellus	66.29	5.00e-74	270.00
IUUC-Csa-024084	Chlorocebus sabaeus	92.50	0.00e+00	659.00
IUUC-Cho-024305	Choloepus hoffmanni	80.91	1.00e-130	459.00
IUUC-Cne-026985	Cryptococcus neoformans	30.84	3.00e-11	64.30
IUUC-Dno-030098	Dasypus novemcinctus	82.16	2.00e-178	618.00
IUUC-Dor-030620	Dipodomys ordii	75.21	2.00e-137	481.00
IUUC-Ete-032306	Echinops telfairi	81.48	1.00e-166	578.00
IUUC-Fca-035950	Felis catus	82.11	1.00e-114	405.00
IUUC-Fal-037429	Ficedula albicollis	66.13	2.00e-134	471.00
IUUC-Fso-038141	Fusarium solani	41.25	2.00e-15	77.00
IUUC-Gga-041201	Gallus gallus	65.19	5.00e-132	464.00
IUUC-Ggo-045429	Gorilla gorilla	92.78	0.00e+00	645.00
IUUC-Hsa-046191	Homo sapiens	91.00	0.00e+00	679.00
IUUC-Itr-048018	Ictidomys tridecemlineatus	79.30	2.00e-155	541.00
IUUC-Lch-049498	Latimeria chalumnae	62.94	3.00e-130	458.00
IUUC-Laf-054239	Loxodonta africana	67.62	2.00e-127	448.00
IUUC-Meu-056382	Macropus eugenii	72.70	3.00e-149	521.00
IUUC-Mor-056917	Magnaporthe oryzae	43.94	1.00e-12	67.80
IUUC-Mga-059435	Meleagris gallopavo	66.14	4.00e-66	243.00
IUUC-Mmr-061513	Microcebus murinus	81.64	5.00e-170	590.00
IUUC-Mdo-063028	Monodelphis domestica	73.22	2.00e-152	531.00
IUUC-Mmu-063545	Mus musculus	75.27	1.00e-151	529.00
IUUC-Mpu-066370	Mustela putorius furo	82.93	5.00e-169	587.00
IUUC-Mlu-067271	Myotis lucifugus	74.04	1.00e-130	459.00
IUUC-Nle-069207	Nomascus leucogenys	91.75	0.00e+00	674.00
IUUC-Opr-070704	Ochotona princeps	70.45	4.00e-92	330.00
IUUC-Oan-072837	Ornithorhynchus anatinus	66.05	3.00e-136	478.00
IUUC-Ocu-074671	Oryctolagus cuniculus	78.67	4.00e-118	417.00
IUUC-Oga-089083	Otolemur garnettii	82.93	5.00e-174	603.00
IUUC-Oar-089254	Ovis aries	80.00	8.00e-109	385.00
IUUC-Ptr-090940	Pan troglodytes	92.43	0.00e+00	663.00
IUUC-Pan-092636	Papio anubis	92.05	0.00e+00	649.00
IUUC-Psi-093435	Pelodiscus sinensis	71.97	4.00e-93	333.00
IUUC-Pab-098525	Pongo abelii	91.21	0.00e+00	644.00
IUUC-Pva-102395	Pteropus vampyrus	80.82	2.00e-170	591.00
IUUC-Pgr-103263	Puccinia graminis	43.84	2.00e-11	64.70
IUUC-Rno-105789	Rattus norvegicus	75.69	7.00e-149	520.00
IUUC-Sha-107305	Sarcophilus harrisii	68.64	4.00e-91	327.00
IUUC-Ssc-115598	Sus scrofa	81.23	3.00e-166	577.00
IUUC-Tgu-116463	Taeniopygia guttata	65.83	1.00e-129	455.00
IUUC-Tsy-118915	Tarsius syrichta	80.89	5.00e-107	380.00
IUUC-Tre-121978	Trichoderma reesei	48.98	3.00e-12	66.60
IUUC-Tme-126970	Tuber melanosporum	49.06	2.00e-12	67.80
IUUC-Tbe-127906	Tupaia belangeri	63.67	2.00e-77	281.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence