iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116463

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01012935

Gene Name

RNF149

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000009945.1	ENSTGUT00000010372.1	ENSTGUP00000010263.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.10e-08	32.9	229	270

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C e +  kd +++lpC+H+fh++C+  w         + +CP C+
   Q: 229  CAVCIENYklKDTVRILPCKHIFHRTCIDPW------LLDHRTCPMCK 270
           ******9988777******************......9999******6 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

EPFSNDTASG STESGRYGDS SPKESARGHV GIPRGASPRH MEGCAADTDY DVPLPPGGRG 60
SPEGDPPTWI ALVARGGCTF KDKVTNAARK RAAAVVIYNE ARFGNSTVSM SHLGTGNTVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAACCGTTCA GCAATGACAC TGCAAGCGGC AGCACGGAGA GCGGCCGCTA CGGGGACAGC 60
TCGCCCAAGG AGAGCGCTCG GGGCCATGTG GGCATTCCCC GCGGCGCCTC GCCCCGCCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0035690--P:cellular response to drug
GO:0043409--P:negative regulation of MAPK cascade
GO:0031647--P:regulation of protein stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001968	Ailuropoda melanoleuca	69.38	5.00e-127	447.00
IUUC-Apl-004109	Anas platyrhynchos	96.64	7.00e-136	475.00
IUUC-Bta-012340	Bos taurus	65.54	1.00e-122	432.00
IUUC-Cja-019566	Callithrix jacchus	65.28	2.00e-125	441.00
IUUC-Cfa-020289	Canis familiaris	72.80	4.00e-91	326.00
IUUC-Cpo-021916	Cavia porcellus	53.16	4.00e-64	237.00
IUUC-Csa-024084	Chlorocebus sabaeus	67.40	1.00e-125	442.00
IUUC-Cho-024305	Choloepus hoffmanni	69.55	1.00e-111	395.00
IUUC-Dno-030098	Dasypus novemcinctus	68.89	1.00e-135	475.00
IUUC-Dor-030620	Dipodomys ordii	61.74	1.00e-106	379.00
IUUC-Ete-032306	Echinops telfairi	71.10	3.00e-134	471.00
IUUC-Fca-035950	Felis catus	73.17	1.00e-101	361.00
IUUC-Fal-037429	Ficedula albicollis	97.53	0.00e+00	681.00
IUUC-Fso-038141	Fusarium solani	40.51	3.00e-14	72.80
IUUC-Gga-041201	Gallus gallus	90.91	6.00e-170	589.00
IUUC-Ggo-045429	Gorilla gorilla	67.50	4.00e-126	443.00
IUUC-Hsa-046191	Homo sapiens	68.06	9.00e-125	439.00
IUUC-Itr-048018	Ictidomys tridecemlineatus	64.82	7.00e-117	413.00
IUUC-Lch-049498	Latimeria chalumnae	67.40	5.00e-135	473.00
IUUC-Laf-054239	Loxodonta africana	62.14	1.00e-109	389.00
IUUC-Meu-056382	Macropus eugenii	73.33	6.00e-135	473.00
IUUC-Mga-059435	Meleagris gallopavo	95.85	8.00e-92	328.00
IUUC-Mmr-061513	Microcebus murinus	65.63	3.00e-120	424.00
IUUC-Mdo-063028	Monodelphis domestica	75.78	7.00e-145	506.00
IUUC-Mmu-063545	Mus musculus	65.35	4.00e-117	414.00
IUUC-Mpu-066370	Mustela putorius furo	66.39	1.00e-122	432.00
IUUC-Mlu-067271	Myotis lucifugus	64.86	3.00e-109	387.00
IUUC-Nle-069207	Nomascus leucogenys	67.50	4.00e-125	441.00
IUUC-Opr-070704	Ochotona princeps	64.61	5.00e-85	306.00
IUUC-Oan-072837	Ornithorhynchus anatinus	74.26	6.00e-137	479.00
IUUC-Ocu-074671	Oryctolagus cuniculus	68.44	2.00e-98	351.00
IUUC-Oga-089083	Otolemur garnettii	66.30	3.00e-124	437.00
IUUC-Oar-089254	Ovis aries	70.54	1.00e-94	338.00
IUUC-Ptr-090940	Pan troglodytes	68.61	5.00e-127	447.00
IUUC-Pan-092636	Papio anubis	67.13	3.00e-125	441.00
IUUC-Psi-093435	Pelodiscus sinensis	91.36	9.00e-123	431.00
IUUC-Pab-098525	Pongo abelii	67.51	1.00e-123	436.00
IUUC-Pva-102395	Pteropus vampyrus	67.78	2.00e-132	464.00
IUUC-Pgr-103263	Puccinia graminis	42.86	2.00e-10	60.80
IUUC-Ptt-103778	Puccinia triticina	38.46	2.00e-09	54.30
IUUC-Rno-105789	Rattus norvegicus	65.92	2.00e-118	418.00
IUUC-Sha-107305	Sarcophilus harrisii	75.32	7.00e-100	355.00
IUUC-Ssc-115598	Sus scrofa	65.28	8.00e-116	409.00
IUUC-Tsy-118915	Tarsius syrichta	68.70	7.00e-90	322.00
IUUC-Tme-126970	Tuber melanosporum	49.06	7.00e-13	68.60
IUUC-Tbe-127906	Tupaia belangeri	72.67	2.00e-66	244.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence