iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000010003.1	ENSSHAT00000011737.1	ENSSHAP00000011641.1
ENSSHAG00000010003.1	ENSSHAT00000011738.1	ENSSHAP00000011642.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	5.60e-06	26.5	34	94
E3 activity/RING/RING	6.20e-07	30.0	38	77

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrl 64
             f C++ l + ++P  + +G+++  s+I   l++++ tcP +r+ l +e +     ++++
   Q: 34   TSFDCSVCLGVLHQPIRTRCGHVFCHSCISTSLRNSKWTCPYCRAYLPSEGVPATDIMKKM 94
           579**********************************9********988877666666665 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C++Cl  + + p+ ++CgHvf+++C+         + + +++CP+Cr
   Q: 38   CSVCLGVLHQ-PIRTRCGHVFCHSCIsTS------LRNSKWTCPYCR 77
           ********99.888***********9444......4**********8 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MGSALSSDSG RAAPATRSTP SALPARSEVE LPVTSFDCSV CLGVLHQPIR TRCGHVFCHS 60
CISTSLRNSK WTCPYCRAYL PSEGVPATDI MKKMKAVYQN CTECNTQVCL SEMRAHIKTC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGGTTTTGA ACACCAGTTT CAGGAGTAGT ACATCGCCAT GCAATTGTTT GCCTCTTGAC 60
CCCCTTAATC TCCCACATTG GTTAAGGACT GTATATTCCT GAGAAGTGCA AACAACCTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR008598--Di19_Zn_binding_dom
IPR034734--ZF_C2HC_RNF
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51803--ZF_C2HC_RNF
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF05605--zf-Di19

SMART

SM00184--RING

Gene Ontology

GO:0000139--C:Golgi membrane
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0039536--P:negative regulation of RIG-I signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001992	Ailuropoda melanoleuca	75.11	8.00e-107	379.00
IUUC-Aca-004839	Anolis carolinensis	63.84	4.00e-68	249.00
IUUC-Bgr-011969	Blumeria graminis	38.46	1.00e-07	51.20
IUUC-Bta-012827	Bos taurus	71.98	1.00e-102	365.00
IUUC-Cja-018794	Callithrix jacchus	75.54	8.00e-107	379.00
IUUC-Cfa-021234	Canis familiaris	76.78	7.00e-99	352.00
IUUC-Cpo-022412	Cavia porcellus	69.96	4.00e-95	340.00
IUUC-Csa-023406	Chlorocebus sabaeus	75.11	8.00e-106	375.00
IUUC-Cho-024427	Choloepus hoffmanni	63.84	3.00e-64	236.00
IUUC-Dno-030085	Dasypus novemcinctus	75.11	3.00e-106	377.00
IUUC-Dor-030911	Dipodomys ordii	56.65	4.00e-60	223.00
IUUC-Ete-032469	Echinops telfairi	73.39	2.00e-102	364.00
IUUC-Eca-034352	Equus caballus	76.82	1.00e-108	385.00
IUUC-Eeu-034889	Erinaceus europaeus	66.95	5.00e-89	320.00
IUUC-Fca-036116	Felis catus	76.17	7.00e-100	355.00
IUUC-Hsa-046518	Homo sapiens	74.68	5.00e-105	373.00
IUUC-Itr-048344	Ictidomys tridecemlineatus	78.53	9.00e-85	305.00
IUUC-Laf-053363	Loxodonta africana	76.17	4.00e-106	376.00
IUUC-Meu-056101	Macropus eugenii	89.70	1.00e-108	385.00
IUUC-Mdo-062046	Monodelphis domestica	89.70	1.00e-114	405.00
IUUC-Mmu-063184	Mus musculus	69.29	2.00e-48	184.00
IUUC-Mpu-065708	Mustela putorius furo	73.82	5.00e-105	373.00
IUUC-Mlu-067561	Myotis lucifugus	73.45	8.00e-80	288.00
IUUC-Nle-069665	Nomascus leucogenys	73.49	2.00e-94	337.00
IUUC-Opr-070301	Ochotona princeps	63.52	2.00e-85	308.00
IUUC-Ocu-074562	Oryctolagus cuniculus	75.40	2.00e-55	206.00
IUUC-Oga-088958	Otolemur garnettii	76.39	6.00e-108	382.00
IUUC-Oar-089541	Ovis aries	73.30	4.00e-80	290.00
IUUC-Ptr-090989	Pan troglodytes	75.11	3.00e-106	377.00
IUUC-Pan-092372	Papio anubis	75.54	2.00e-106	377.00
IUUC-Pab-098718	Pongo abelii	65.67	2.00e-86	310.00
IUUC-Pca-100453	Procavia capensis	74.68	2.00e-103	367.00
IUUC-Pva-102931	Pteropus vampyrus	76.39	3.00e-102	363.00
IUUC-Rno-105771	Rattus norvegicus	73.58	7.00e-85	306.00
IUUC-Sar-113435	Sorex araneus	76.19	3.00e-56	209.00
IUUC-Ssc-116388	Sus scrofa	75.54	8.00e-107	379.00
IUUC-Tsy-119439	Tarsius syrichta	76.27	1.00e-82	298.00
IUUC-Tbe-127417	Tupaia belangeri	53.17	1.00e-54	205.00
IUUC-Ttr-129212	Tursiops truncatus	75.54	4.00e-107	380.00
IUUC-Uma-129518	Ustilago maydis	39.13	1.00e-06	48.50
IUUC-Vpa-130153	Vicugna pacos	74.68	3.00e-105	374.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence