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Tag Content
UUCD2 ID IUUC-Sha-107051
UUCD1 version UUC-SaH-01062
Ensembl Protein ID ENSSHAP00000007058.1
UniProt Accession G3VV53; G3VV53_SARHA
Genbank Protein ID ENSSHAP00000007058
Protein Name Uncharacterized protein
Genbank Nucleotide ID AEFK01139119
Gene Name USP25
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSHAG00000006133.1 ENSSHAT00000007119.1 ENSSHAP00000007057.1
ENSSHAG00000006133.1 ENSSHAT00000007120.1 ENSSHAP00000007058.1
ENSSHAG00000006133.1 ENSSHAT00000007121.1 ENSSHAP00000007059.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 2.40e-63 214.5 182 662
UBD/Alpha-Helix/UBA 9.00e-06 25.8 32 67
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +GlkN+gNtC++ +v+Q+L+n+ e+r+l+l+       ++l+++++++++ +++++l++lf+ l+ sk+k+v+p++ +++lk++ ++ +
   Q: 182  VGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNynppASAQDLPRNQKEHRNLPFMRELRHLFALLVGSKRKYVDPSRAVDILKDAFKS-N 269
           6******************************99998899999999999999*******************************99997.* PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           g++qqD++Ef++ lld le+++++                  + +ee++ +k k+++ +lF g++    + +  +++ + +e f +++l
   Q: 270  GSQQQDVSEFTHKLLDWLEDAFQM------------------KAEEERDGEKPKNPMLELFYGRFLAVGVLE--GKKFENTEMFGQYPL 338
           **********************32..................2235678999**************777664..444556899****** PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           +v+g +     +l++cLe+ + e e+e+   +++e+  k+    +++++++lP+vL+++L+Rf+f+++ +++eki++k+efp+ L l++
   Q: 339  QVNGFK-----DLHECLEAAMIEGEIES---LHSENSGKS---GQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDR 416
           ******.....9**************96...999998865...589******************************************* PP
   S: 264  fcts..................................................................................... 267
           ++++                                                                                     
   Q: 417  YMHKnreitrikrdeikrlkeyltvlqqrlerylsygsgpkrfplvdvlqyalefasskpvctspvddidassppsgsipsqtlpstae 505
           ****8888888888888888888888888888888888888888888888888888888877777777777777777777777766555 PP
   S: 268  ....peekqke.............................................................................. 274
               +                                                                                    
   Q: 506  qqqgT-----Pselpstsptprsfihkpftqsrippdlpmhpaprhiteeelsvlegclhrwrtevendtrdlqesisrihrtieqmys 589
           55550.....0555555555555666666666666666666666666666666666777777777777777777788888888888888 PP
   S: 275  .....kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                ++ Y+L+av+vH+G+++ GHY+ay+ +++++ W++++D +Vt++++ee ++++      ++aY+l+Y 
   Q: 590  dksmiQVPYRLHAVLVHEGQANAGHYWAYIFDHHQErWMKYNDISVTKSTWEELERDSFggyrnASAYCLMYI 662
           88888***************************77778*******************8779************6 PP
   

   UBD/Alpha-Helix/UBA
   S: 5    dkleqlve.MGF.dreealqaLraannnleaAveyL 38
             l+ql+e +G+ d++  +qaL ++n+nle Av++L
   Q: 32   TFLNQLREiTGInDTQILQQALKDSNGNLELAVAFL 67
           569*******************************98 PP
   
Organism Sarcophilus harrisii
Protein Sequence
(Fasta)
MKFMKTGGGT FAQRRTEGKG WSKLQEAVHQ QTFLNQLREI TGINDTQILQ QALKDSNGNL 60
ELAVAFLTAK NAKTPQQEET TYYQTALPGN DRYISVGSQA DTNVIDLTGD DKDDLQRAIA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sha-107051|DUB,USP;UBD,UBA|Sarcophilus harrisii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCTTATTATT AGTGTACAAT TTTTTGGGGA AAAAAATCTA CTTCAATAAA TATGATCATG 60
GTAAAACTTT GATTAGTGAA CATCCACAAG TTTTCAAATA AAACTGAACT CCAAATTTTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sha-107051|DUB,USP;UBD,UBA|Sarcophilus harrisii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR003903--UIM_dom
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
PF02809--UIM
SMART

SM00726--UIM
Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1904293--P:negative regulation of ERAD pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001340 Ailuropoda melanoleuca 86.46 0.00e+00 1833.00
IUUC-Apl-004030 Anas platyrhynchos 86.95 0.00e+00 1897.00
IUUC-Aca-004753 Anolis carolinensis 67.16 0.00e+00 1035.00
IUUC-Afu-008871 Aspergillus fumigatus 24.65 1.00e-12 68.90
IUUC-Ame-010624 Astyanax mexicanus 71.32 0.00e+00 1118.00
IUUC-Bta-013166 Bos taurus 88.48 0.00e+00 1843.00
IUUC-Cel-018346 Caenorhabditis elegans 29.72 3.00e-29 124.00
IUUC-Cja-019150 Callithrix jacchus 89.52 0.00e+00 1316.00
IUUC-Cfa-020649 Canis familiaris 88.71 0.00e+00 1321.00
IUUC-Cpo-021807 Cavia porcellus 87.02 0.00e+00 1909.00
IUUC-Csa-023388 Chlorocebus sabaeus 89.28 0.00e+00 1342.00
IUUC-Cho-024343 Choloepus hoffmanni 76.52 0.00e+00 925.00
IUUC-Cin-025302 Ciona intestinalis 37.27 4.00e-97 348.00
IUUC-Cme-027167 Cyanidioschyzon merolae 26.44 3.00e-19 90.90
IUUC-Dre-028016 Danio rerio 77.21 0.00e+00 1177.00
IUUC-Dno-029495 Dasypus novemcinctus 86.58 0.00e+00 1321.00
IUUC-Dor-030948 Dipodomys ordii 74.83 0.00e+00 1316.00
IUUC-Fca-035876 Felis catus 89.41 0.00e+00 1863.00
IUUC-Fal-036762 Ficedula albicollis 88.26 0.00e+00 1152.00
IUUC-Fox-037752 Fusarium oxysporum 24.32 9.00e-18 85.90
IUUC-Gmo-039490 Gadus morhua 74.02 0.00e+00 1561.00
IUUC-Gga-040817 Gallus gallus 87.80 0.00e+00 1385.00
IUUC-Gac-042473 Gasterosteus aculeatus 72.41 0.00e+00 1567.00
IUUC-Ggo-044939 Gorilla gorilla 85.17 0.00e+00 1774.00
IUUC-Hsa-046204 Homo sapiens 89.62 0.00e+00 1839.00
IUUC-Kpa-049349 Komagataella pastoris 27.37 2.00e-09 58.50
IUUC-Lch-049572 Latimeria chalumnae 83.31 0.00e+00 1259.00
IUUC-Loc-052070 Lepisosteus oculatus 80.63 0.00e+00 1228.00
IUUC-Laf-054426 Loxodonta africana 89.03 0.00e+00 1726.00
IUUC-Mcc-055858 Macaca mulatta 89.65 0.00e+00 1343.00
IUUC-Mla-058944 Melampsora laricipopulina 23.57 1.00e-11 66.20
IUUC-Mga-059808 Meleagris gallopavo 89.55 0.00e+00 1909.00
IUUC-Mmr-060987 Microcebus murinus 90.81 0.00e+00 1333.00
IUUC-Mmu-064245 Mus musculus 86.83 0.00e+00 1843.00
IUUC-Mpu-066304 Mustela putorius furo 88.58 0.00e+00 1323.00
IUUC-Mlu-067139 Myotis lucifugus 89.22 0.00e+00 1891.00
IUUC-Nfi-068458 Neosartorya fischeri 24.44 1.00e-15 79.30
IUUC-Nle-069075 Nomascus leucogenys 89.33 0.00e+00 1830.00
IUUC-Ont-072150 Oreochromis niloticus 76.64 0.00e+00 1201.00
IUUC-Oan-073054 Ornithorhynchus anatinus 83.52 0.00e+00 1749.00
IUUC-Ocu-074102 Oryctolagus cuniculus 86.96 0.00e+00 1323.00
IUUC-Ola-086529 Oryzias latipes 70.62 0.00e+00 1510.00
IUUC-Oga-088939 Otolemur garnettii 89.23 0.00e+00 1853.00
IUUC-Oar-090266 Ovis aries 89.76 0.00e+00 1328.00
IUUC-Ptr-090546 Pan troglodytes 89.42 0.00e+00 1836.00
IUUC-Pan-092311 Papio anubis 89.52 0.00e+00 1343.00
IUUC-Psi-093459 Pelodiscus sinensis 93.84 0.00e+00 1203.00
IUUC-Pfo-096726 Poecilia formosa 76.11 0.00e+00 1183.00
IUUC-Pab-097608 Pongo abelii 86.66 0.00e+00 1816.00
IUUC-Pca-100718 Procavia capensis 85.30 0.00e+00 1136.00
IUUC-Pva-103150 Pteropus vampyrus 84.81 0.00e+00 1382.00
IUUC-Rno-105727 Rattus norvegicus 86.94 0.00e+00 1813.00
IUUC-Sar-113097 Sorex araneus 81.05 0.00e+00 1705.00
IUUC-Ssc-115877 Sus scrofa 87.11 0.00e+00 1832.00
IUUC-Tgu-117473 Taeniopygia guttata 81.13 0.00e+00 1749.00
IUUC-Tru-118135 Takifugu rubripes 67.45 0.00e+00 1408.00
IUUC-Tsy-119471 Tarsius syrichta 82.58 0.00e+00 1645.00
IUUC-Tni-120139 Tetraodon nigroviridis 68.35 0.00e+00 1328.00
IUUC-Tbe-127549 Tupaia belangeri 83.57 0.00e+00 1759.00
IUUC-Ttr-128896 Tursiops truncatus 82.54 0.00e+00 1749.00
IUUC-Vpa-130500 Vicugna pacos 80.97 0.00e+00 1729.00
IUUC-Xtr-132896 Xenopus tropicalis 83.80 0.00e+00 1789.00
Created Date 25-Jun-2017

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